Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q13733

- AT1A4_HUMAN

UniProt

Q13733 - AT1A4_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Sodium/potassium-transporting ATPase subunit alpha-4

Gene

ATP1A4

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility.

Catalytic activityi

ATP + H2O + Na+(In) + K+(Out) = ADP + phosphate + Na+(Out) + K+(In).

Enzyme regulationi

Specifically inhibited by an endogenous cardiac glycoside, ouabain.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei384 – 38414-aspartylphosphate intermediateBy similarity
Metal bindingi723 – 7231MagnesiumBy similarity
Metal bindingi727 – 7271MagnesiumBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. sodium:potassium-exchanging ATPase activity Source: UniProtKB

GO - Biological processi

  1. ATP biosynthetic process Source: InterPro
  2. ATP hydrolysis coupled proton transport Source: UniProtKB
  3. fertilization Source: Ensembl
  4. ion transmembrane transport Source: Reactome
  5. potassium ion transport Source: UniProtKB
  6. regulation of cellular pH Source: UniProtKB
  7. regulation of membrane potential Source: Ensembl
  8. sodium ion transmembrane transport Source: GOC
  9. sodium ion transport Source: UniProtKB
  10. spermatogenesis Source: Ensembl
  11. sperm motility Source: UniProtKB
  12. transmembrane transport Source: Reactome
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Potassium, Sodium

Enzyme and pathway databases

ReactomeiREACT_25149. Ion transport by P-type ATPases.

Names & Taxonomyi

Protein namesi
Recommended name:
Sodium/potassium-transporting ATPase subunit alpha-4 (EC:3.6.3.9)
Short name:
Na(+)/K(+) ATPase alpha-4 subunit
Alternative name(s):
Sodium pump subunit alpha-4
Gene namesi
Name:ATP1A4
Synonyms:ATP1AL2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:14073. ATP1A4.

Subcellular locationi

Cell membrane 1 Publication; Multi-pass membrane protein 1 Publication
Note: In mature sperm, located in the principle piece of the sperm flagellum.

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 9595CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei96 – 11621HelicalSequence AnalysisAdd
BLAST
Topological domaini117 – 13923ExtracellularSequence AnalysisAdd
BLAST
Transmembranei140 – 16021HelicalSequence AnalysisAdd
BLAST
Topological domaini161 – 296136CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei297 – 31620HelicalSequence AnalysisAdd
BLAST
Topological domaini317 – 32812ExtracellularSequence AnalysisAdd
BLAST
Transmembranei329 – 34618HelicalSequence AnalysisAdd
BLAST
Topological domaini347 – 778432CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei779 – 79820HelicalSequence AnalysisAdd
BLAST
Topological domaini799 – 80810ExtracellularSequence Analysis
Transmembranei809 – 82921HelicalSequence AnalysisAdd
BLAST
Topological domaini830 – 84920CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei850 – 87223HelicalSequence AnalysisAdd
BLAST
Topological domaini873 – 92452ExtracellularSequence AnalysisAdd
BLAST
Transmembranei925 – 94420HelicalSequence AnalysisAdd
BLAST
Topological domaini945 – 95713CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei958 – 97619HelicalSequence AnalysisAdd
BLAST
Topological domaini977 – 99115ExtracellularSequence AnalysisAdd
BLAST
Transmembranei992 – 101221HelicalSequence AnalysisAdd
BLAST
Topological domaini1013 – 102917CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of plasma membrane Source: UniProtKB
  2. plasma membrane Source: Reactome
  3. sodium:potassium-exchanging ATPase complex Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA65.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10291029Sodium/potassium-transporting ATPase subunit alpha-4PRO_0000046303Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei949 – 9491Phosphoserine; by PKABy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ13733.
PaxDbiQ13733.
PRIDEiQ13733.

PTM databases

PhosphoSiteiQ13733.

Expressioni

Tissue specificityi

Specifically expressed in testis. Found in very low levels in skeletal muscle. Expressed in mature sperm (at protein level).

Gene expression databases

BgeeiQ13733.
CleanExiHS_ATP1A4.
ExpressionAtlasiQ13733. baseline and differential.
GenevestigatoriQ13733.

Organism-specific databases

HPAiCAB033628.

Interactioni

Subunit structurei

Composed of three subunits: alpha (catalytic), beta and gamma.

Protein-protein interaction databases

BioGridi106970. 6 interactions.
STRINGi9606.ENSP00000357060.

Structurei

3D structure databases

ProteinModelPortaliQ13733.
SMRiQ13733. Positions 38-1029.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni90 – 923Interaction with phosphoinositide-3 kinaseBy similarity

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0474.
GeneTreeiENSGT00760000119003.
HOVERGENiHBG004298.
InParanoidiQ13733.
KOiK01539.
OMAiKSSDTWF.
OrthoDBiEOG7327N0.
PhylomeDBiQ13733.
TreeFamiTF312838.

Family and domain databases

Gene3Di1.20.1110.10. 2 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
InterProiIPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR005775. ATPase_P-typ_Na/K_IIC.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
[Graphical view]
PfamiPF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF00702. Hydrolase. 1 hit.
[Graphical view]
PRINTSiPR00119. CATATPASE.
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 2 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01106. ATPase-IIC_X-K. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q13733-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGLWGKKGTV APHDQSPRRR PKKGLIKKKM VKREKQKRNM EELKKEVVMD
60 70 80 90 100
DHKLTLEELS TKYSVDLTKG HSHQRAKEIL TRGGPNTVTP PPTTPEWVKF
110 120 130 140 150
CKQLFGGFSL LLWTGAILCF VAYSIQIYFN EEPTKDNLYL SIVLSVVVIV
160 170 180 190 200
TGCFSYYQEA KSSKIMESFK NMVPQQALVI RGGEKMQINV QEVVLGDLVE
210 220 230 240 250
IKGGDRVPAD LRLISAQGCK VDNSSLTGES EPQSRSPDFT HENPLETRNI
260 270 280 290 300
CFFSTNCVEG TARGIVIATG DSTVMGRIAS LTSGLAVGQT PIAAEIEHFI
310 320 330 340 350
HLITVVAVFL GVTFFALSLL LGYGWLEAII FLIGIIVANV PEGLLATVTV
360 370 380 390 400
CLTLTAKRMA RKNCLVKNLE AVETLGSTST ICSDKTGTLT QNRMTVAHMW
410 420 430 440 450
FDMTVYEADT TEEQTGKTFT KSSDTWFMLA RIAGLCNRAD FKANQEILPI
460 470 480 490 500
AKRATTGDAS ESALLKFIEQ SYSSVAEMRE KNPKVAEIPF NSTNKYQMSI
510 520 530 540 550
HLREDSSQTH VLMMKGAPER ILEFCSTFLL NGQEYSMNDE MKEAFQNAYL
560 570 580 590 600
ELGGLGERVL GFCFLNLPSS FSKGFPFNTD EINFPMDNLC FVGLISMIDP
610 620 630 640 650
PRAAVPDAVS KCRSAGIKVI MVTGDHPITA KAIAKGVGII SEGTETAEEV
660 670 680 690 700
AARLKIPISK VDASAAKAIV VHGAELKDIQ SKQLDQILQN HPEIVFARTS
710 720 730 740 750
PQQKLIIVEG CQRLGAVVAV TGDGVNDSPA LKKADIGIAM GISGSDVSKQ
760 770 780 790 800
AADMILLDDN FASIVTGVEE GRLIFDNLKK SIMYTLTSNI PEITPFLMFI
810 820 830 840 850
ILGIPLPLGT ITILCIDLGT DMVPAISLAY ESAESDIMKR LPRNPKTDNL
860 870 880 890 900
VNHRLIGMAY GQIGMIQALA GFFTYFVILA ENGFRPVDLL GIRLHWEDKY
910 920 930 940 950
LNDLEDSYGQ QWTYEQRKVV EFTCQTAFFV TIVVVQWADL IISKTRRNSL
960 970 980 990 1000
FQQGMRNKVL IFGILEETLL AAFLSYTPGM DVALRMYPLK ITWWLCAIPY
1010 1020
SILIFVYDEI RKLLIRQHPD GWVERETYY
Length:1,029
Mass (Da):114,166
Last modified:October 10, 2002 - v3
Checksum:i69958248424D2C0B
GO
Isoform 2 (identifier: Q13733-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-864: Missing.

Note: No experimental confirmation available.

Show »
Length:165
Mass (Da):19,609
Checksum:i5789093F12A8AC94
GO

Sequence cautioni

The sequence AAQ07964.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAC05228.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti155 – 1551S → W in AAA60941. (PubMed:7809153)Curated
Sequence conflicti991 – 101727ITWWL…LLIRQ → WSFALTAQAGVKWRILGLLQ PLPPRFK in BAC05228. (PubMed:14702039)CuratedAdd
BLAST

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti83 – 831G → D.1 Publication
Corresponds to variant rs6427504 [ dbSNP | Ensembl ].
VAR_048375
Natural varianti297 – 2971E → K.
Corresponds to variant rs17368402 [ dbSNP | Ensembl ].
VAR_048376
Natural varianti541 – 5411M → R.
Corresponds to variant rs16831482 [ dbSNP | Ensembl ].
VAR_048377
Natural varianti586 – 5861M → I.
Corresponds to variant rs7528360 [ dbSNP | Ensembl ].
VAR_048378

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 864864Missing in isoform 2. 1 PublicationVSP_007364Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF506797 mRNA. Translation: AAQ07964.1. Different initiation.
AL121987 Genomic DNA. Translation: CAI15274.1.
AF421887 Genomic DNA. Translation: AAL35818.1.
AF310646
, AF430843, AF390027, AY039031 Genomic DNA. Translation: AAK72396.2.
AF459737 mRNA. Translation: AAL66357.1.
AF352828 Genomic DNA. Translation: AAM20793.1.
AH002997 Genomic DNA. Translation: AAA60941.1.
AK098076 mRNA. Translation: BAC05228.1. Different initiation.
BC028297 mRNA. Translation: AAH28297.1.
BC094801 mRNA. Translation: AAH94801.1.
CCDSiCCDS1197.1. [Q13733-1]
CCDS44255.1. [Q13733-2]
RefSeqiNP_001001734.1. NM_001001734.1. [Q13733-2]
NP_653300.2. NM_144699.3. [Q13733-1]
UniGeneiHs.662219.

Genome annotation databases

EnsembliENST00000368081; ENSP00000357060; ENSG00000132681. [Q13733-1]
ENST00000470705; ENSP00000433094; ENSG00000132681. [Q13733-2]
GeneIDi480.
KEGGihsa:480.
UCSCiuc001fve.4. human. [Q13733-1]
uc001fvh.3. human. [Q13733-2]

Polymorphism databases

DMDMi23830899.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF506797 mRNA. Translation: AAQ07964.1 . Different initiation.
AL121987 Genomic DNA. Translation: CAI15274.1 .
AF421887 Genomic DNA. Translation: AAL35818.1 .
AF310646
, AF430843 , AF390027 , AY039031 Genomic DNA. Translation: AAK72396.2 .
AF459737 mRNA. Translation: AAL66357.1 .
AF352828 Genomic DNA. Translation: AAM20793.1 .
AH002997 Genomic DNA. Translation: AAA60941.1 .
AK098076 mRNA. Translation: BAC05228.1 . Different initiation.
BC028297 mRNA. Translation: AAH28297.1 .
BC094801 mRNA. Translation: AAH94801.1 .
CCDSi CCDS1197.1. [Q13733-1 ]
CCDS44255.1. [Q13733-2 ]
RefSeqi NP_001001734.1. NM_001001734.1. [Q13733-2 ]
NP_653300.2. NM_144699.3. [Q13733-1 ]
UniGenei Hs.662219.

3D structure databases

ProteinModelPortali Q13733.
SMRi Q13733. Positions 38-1029.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 106970. 6 interactions.
STRINGi 9606.ENSP00000357060.

Chemistry

ChEMBLi CHEMBL2095186.

PTM databases

PhosphoSitei Q13733.

Polymorphism databases

DMDMi 23830899.

Proteomic databases

MaxQBi Q13733.
PaxDbi Q13733.
PRIDEi Q13733.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000368081 ; ENSP00000357060 ; ENSG00000132681 . [Q13733-1 ]
ENST00000470705 ; ENSP00000433094 ; ENSG00000132681 . [Q13733-2 ]
GeneIDi 480.
KEGGi hsa:480.
UCSCi uc001fve.4. human. [Q13733-1 ]
uc001fvh.3. human. [Q13733-2 ]

Organism-specific databases

CTDi 480.
GeneCardsi GC01P160121.
HGNCi HGNC:14073. ATP1A4.
HPAi CAB033628.
MIMi 607321. gene.
neXtProti NX_Q13733.
PharmGKBi PA65.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0474.
GeneTreei ENSGT00760000119003.
HOVERGENi HBG004298.
InParanoidi Q13733.
KOi K01539.
OMAi KSSDTWF.
OrthoDBi EOG7327N0.
PhylomeDBi Q13733.
TreeFami TF312838.

Enzyme and pathway databases

Reactomei REACT_25149. Ion transport by P-type ATPases.

Miscellaneous databases

ChiTaRSi ATP1A4. human.
GeneWikii ATP1A4.
GenomeRNAii 480.
NextBioi 1989.
PROi Q13733.
SOURCEi Search...

Gene expression databases

Bgeei Q13733.
CleanExi HS_ATP1A4.
ExpressionAtlasi Q13733. baseline and differential.
Genevestigatori Q13733.

Family and domain databases

Gene3Di 1.20.1110.10. 2 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
InterProi IPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR005775. ATPase_P-typ_Na/K_IIC.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
[Graphical view ]
Pfami PF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF00702. Hydrolase. 1 hit.
[Graphical view ]
PRINTSi PR00119. CATATPASE.
SMARTi SM00831. Cation_ATPase_N. 1 hit.
[Graphical view ]
SUPFAMi SSF56784. SSF56784. 2 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsi TIGR01106. ATPase-IIC_X-K. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEi PS00154. ATPASE_E1_E2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The human Na,K-ATPase alpha 4 isoform is a ouabain-sensitive alpha isoform that is expressed in sperm."
    Hlivko J.T., Chakraborty S., Hlivko T.J., Sengupta A., James P.F.
    Mol. Reprod. Dev. 73:101-115(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, ENZYME REGULATION.
    Tissue: Testis.
  2. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Tissue: Testis and Urinary bladder.
  4. "Physical mapping and characterization of the human Na,K-ATPase isoform, ATP1A4."
    Keryanov S., Gardner K.L.
    Gene 292:151-166(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-69 AND 138-1029 (ISOFORM 1).
  5. "A putative fourth Na+,K(+)-ATPase alpha-subunit gene is expressed in testis."
    Shamraj O.I., Lingrel J.B.
    Proc. Natl. Acad. Sci. U.S.A. 91:12952-12956(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 50-220 (ISOFORM 1), VARIANT ASP-83.
    Tissue: Testis.
  6. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 549-1017 (ISOFORM 1).
    Tissue: Trachea.

Entry informationi

Entry nameiAT1A4_HUMAN
AccessioniPrimary (citable) accession number: Q13733
Secondary accession number(s): Q504T2
, Q7Z4I9, Q8TBN8, Q8WXA7, Q8WXH7, Q8WY13
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: October 10, 2002
Last modified: November 26, 2014
This is version 142 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3