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Q136E1 (KDSA_RHOPS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2-dehydro-3-deoxyphosphooctonate aldolase
EC=2.5.1.55
Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase
KDO-8-phosphate synthase
Short name=KDO 8-P synthase
Short name=KDOPS
Phospho-2-dehydro-3-deoxyoctonate aldolase
Gene names
Name:kdsA
Ordered Locus Names:RPD_2820
OrganismRhodopseudomonas palustris (strain BisB5) [Complete proteome] [HAMAP]
Taxonomic identifier316057 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length287 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. HAMAP MF_00056

Pathway

Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. HAMAP MF_00056

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP MF_00056

Subcellular location

Cytoplasm By similarity HAMAP MF_00056.

Sequence similarities

Belongs to the KdsA family.

Ontologies

Keywords
   Biological processLipopolysaccharide biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlipopolysaccharide biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-deoxy-8-phosphooctulonate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2872872-dehydro-3-deoxyphosphooctonate aldolase HAMAP MF_00056
PRO_0000304480

Sequences

Sequence LengthMass (Da)Tools
Q136E1 [UniParc].

Last modified October 31, 2006. Version 1.
Checksum: 4D1DABC880568612

FASTA28729,900
        10         20         30         40         50         60 
MNKSIAPAPV VAAGDVKFGN SLPLSVIAGP CQLESRAHAL EVASALKEIA TRLGIGLVYK 

        70         80         90        100        110        120 
TSFDKANRTS AASARGIGLD AALAIFAEIR DSVGLPVLTD VHEAEQCARA AEAVDILQIP 

       130        140        150        160        170        180 
AFLCRQTDLL LAAAATGRIV NVKKGQFLAP WDMGNVVAKI TTAGNQKVLV TERGASFGYN 

       190        200        210        220        230        240 
TLVSDMRALP IMARTTGAPV IFDATHSVQQ PGGKGTSSGG EREFVPVLAR AAVAVGVAGV 

       250        260        270        280 
FIETHPDPDH APSDGPNMVP LRDFEALLRT LMEFDALAKK RPGAGTI

« Hide

References

[1]"Complete sequence of Rhodopseudomonas palustris BisB5."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Pelletier D.A., Kyrpides N., Lykidis A., Oda Y., Harwood C.S., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BisB5.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000283 Genomic DNA. Translation: ABE40048.1.
RefSeqYP_569949.1. NC_007958.1.

3D structure databases

ProteinModelPortalQ136E1.
SMRQ136E1. Positions 23-282.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ136E1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4023318.
GenomeReviewsGene locus RPD_2820 in contig CP000283_GR.
KEGGrpd:RPD_2820.
PATRIC23280685. VBIRhoPal120395_2908.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2877.
HOGENOMHBG575990.
OMAESRDHAF.
ProtClustDBPRK05198.

Enzyme and pathway databases

BioCycRPAL316057:RPD_2820-MONOMER.

Family and domain databases

HAMAPMF_00056. KDO8P_synth.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006269. KDO8P_synthase.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01627.
PANTHERPTHR21057:SF2. KDO8P_synthase. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR01362. KDO8P_synth. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKDSA_RHOPS
AccessionPrimary (citable) accession number: Q136E1
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 31, 2006
Last modified: January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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