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Q136A2 (Y2859_RHOPS) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable RNA methyltransferase RPD_2859

EC=2.1.1.-
Gene names
Ordered Locus Names:RPD_2859
OrganismRhodopseudomonas palustris (strain BisB5) [Complete proteome] [HAMAP]
Taxonomic identifier316057 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine By similarity.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the radical SAM superfamily. RlmN family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Ligand4Fe-4S
Iron
Iron-sulfur
Metal-binding
S-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   PTMDisulfide bond
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processrRNA processing

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function4 iron, 4 sulfur cluster binding

Inferred from electronic annotation. Source: UniProtKB-KW

RNA methyltransferase activity

Inferred from electronic annotation. Source: InterPro

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 359359Probable RNA methyltransferase RPD_2859
PRO_0000350372

Regions

Region162 – 1632S-adenosyl-L-methionine binding By similarity
Region217 – 2193S-adenosyl-L-methionine binding By similarity

Sites

Active site991Proton acceptor Potential
Active site3361S-methylcysteine intermediate By similarity
Metal binding1191Iron-sulfur (4Fe-4S-S-AdoMet) By similarity
Metal binding1231Iron-sulfur (4Fe-4S-S-AdoMet) By similarity
Metal binding1261Iron-sulfur (4Fe-4S-S-AdoMet) By similarity
Binding site1941S-adenosyl-L-methionine By similarity
Binding site2931S-adenosyl-L-methionine; via amide nitrogen and carbonyl oxygen By similarity

Amino acid modifications

Disulfide bond112 ↔ 336(transient) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q136A2 [UniParc].

Last modified October 31, 2006. Version 1.
Checksum: CBEDC1DC5F019B71

FASTA35939,815
        10         20         30         40         50         60 
MASAQRHSTP DLVRQRDPAG VSGLSLGLTS SEFAGLHEGA VPDVTYRELF FPHADPPRRL 

        70         80         90        100        110        120 
QNWARSRGVR LRTLTRIGRD QGGRSEKMLF GLHDGYAVES VLIRRFDGHT ACISSQVGCA 

       130        140        150        160        170        180 
FACRFCASGQ AGLMRNLEAG EIVEQVVRLG PKVNRIVFMG IGEPLNNYQQ VLKAIRILRD 

       190        200        210        220        230        240 
RQGMNFPTTG ITLSTIGIPK ALKQLREEHL AINLTISLHA TTQEVRDRLI PGARKHPLGE 

       250        260        270        280        290        300 
VVERACAWAR RHNRPVTFAY LVLPGINDSI ADARRLAAML RDSPARVNLM RWNPVDGVGL 

       310        320        330        340        350 
QRTPDRSLAH FRTTLENALV PVVVRDTQGR DISAACGQLW LRDLKGLPVG NRPRQGRMT 

« Hide

References

[1]"Complete sequence of Rhodopseudomonas palustris BisB5."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Pelletier D.A., Kyrpides N., Lykidis A., Oda Y., Harwood C.S., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BisB5.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000283 Genomic DNA. Translation: ABE40087.1.
RefSeqYP_569988.1. NC_007958.1.

3D structure databases

ProteinModelPortalQ136A2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING316057.RPD_2859.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE40087; ABE40087; RPD_2859.
GeneID4023357.
KEGGrpd:RPD_2859.
PATRIC23280771. VBIRhoPal120395_2951.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0820.
HOGENOMHOG000217991.
KOK06941.
OMAELGDGQM.
OrthoDBEOG6DJZ2N.

Enzyme and pathway databases

BioCycRPAL316057:GHDC-2903-MONOMER.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR013785. Aldolase_TIM.
IPR006638. Elp3/MiaB/NifB.
IPR004383. rRNA_lsu_MTrfase_RlmN/Cfr.
IPR007197. rSAM.
[Graphical view]
PANTHERPTHR30544. PTHR30544. 1 hit.
PfamPF04055. Radical_SAM. 1 hit.
[Graphical view]
PIRSFPIRSF006004. CHP00048. 1 hit.
SMARTSM00729. Elp3. 1 hit.
[Graphical view]
TIGRFAMsTIGR00048. TIGR00048. 1 hit.
ProtoNetSearch...

Entry information

Entry nameY2859_RHOPS
AccessionPrimary (citable) accession number: Q136A2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: October 31, 2006
Last modified: April 16, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families