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Q136A2

- Y2859_RHOPS

UniProt

Q136A2 - Y2859_RHOPS

Protein

Probable RNA methyltransferase RPD_2859

Gene

RPD_2859

Organism
Rhodopseudomonas palustris (strain BisB5)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (31 Oct 2006)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine By similarity.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei99 – 991Proton acceptorSequence Analysis
    Metal bindingi119 – 1191Iron-sulfur (4Fe-4S-S-AdoMet)By similarity
    Metal bindingi123 – 1231Iron-sulfur (4Fe-4S-S-AdoMet)By similarity
    Metal bindingi126 – 1261Iron-sulfur (4Fe-4S-S-AdoMet)By similarity
    Binding sitei194 – 1941S-adenosyl-L-methionineBy similarity
    Binding sitei293 – 2931S-adenosyl-L-methionine; via amide nitrogen and carbonyl oxygenBy similarity
    Active sitei336 – 3361S-methylcysteine intermediateBy similarity

    GO - Molecular functioni

    1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. RNA methyltransferase activity Source: InterPro

    GO - Biological processi

    1. rRNA processing Source: InterPro

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Ligandi

    4Fe-4S, Iron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciRPAL316057:GHDC-2903-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable RNA methyltransferase RPD_2859 (EC:2.1.1.-)
    Gene namesi
    Ordered Locus Names:RPD_2859
    OrganismiRhodopseudomonas palustris (strain BisB5)
    Taxonomic identifieri316057 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
    ProteomesiUP000001818: Chromosome

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 359359Probable RNA methyltransferase RPD_2859PRO_0000350372Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi112 ↔ 336(transient)By similarity

    Keywords - PTMi

    Disulfide bond

    Interactioni

    Protein-protein interaction databases

    STRINGi316057.RPD_2859.

    Structurei

    3D structure databases

    ProteinModelPortaliQ136A2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni162 – 1632S-adenosyl-L-methionine bindingBy similarity
    Regioni217 – 2193S-adenosyl-L-methionine bindingBy similarity

    Sequence similaritiesi

    Belongs to the radical SAM superfamily. RlmN family.Curated

    Phylogenomic databases

    eggNOGiCOG0820.
    HOGENOMiHOG000217991.
    KOiK06941.
    OMAiCAFACRF.
    OrthoDBiEOG6DJZ2N.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR013785. Aldolase_TIM.
    IPR006638. Elp3/MiaB/NifB.
    IPR004383. rRNA_lsu_MTrfase_RlmN/Cfr.
    IPR007197. rSAM.
    [Graphical view]
    PANTHERiPTHR30544. PTHR30544. 1 hit.
    PfamiPF04055. Radical_SAM. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006004. CHP00048. 1 hit.
    SMARTiSM00729. Elp3. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00048. TIGR00048. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q136A2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASAQRHSTP DLVRQRDPAG VSGLSLGLTS SEFAGLHEGA VPDVTYRELF    50
    FPHADPPRRL QNWARSRGVR LRTLTRIGRD QGGRSEKMLF GLHDGYAVES 100
    VLIRRFDGHT ACISSQVGCA FACRFCASGQ AGLMRNLEAG EIVEQVVRLG 150
    PKVNRIVFMG IGEPLNNYQQ VLKAIRILRD RQGMNFPTTG ITLSTIGIPK 200
    ALKQLREEHL AINLTISLHA TTQEVRDRLI PGARKHPLGE VVERACAWAR 250
    RHNRPVTFAY LVLPGINDSI ADARRLAAML RDSPARVNLM RWNPVDGVGL 300
    QRTPDRSLAH FRTTLENALV PVVVRDTQGR DISAACGQLW LRDLKGLPVG 350
    NRPRQGRMT 359
    Length:359
    Mass (Da):39,815
    Last modified:October 31, 2006 - v1
    Checksum:iCBEDC1DC5F019B71
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000283 Genomic DNA. Translation: ABE40087.1.
    RefSeqiWP_011503264.1. NC_007958.1.
    YP_569988.1. NC_007958.1.

    Genome annotation databases

    EnsemblBacteriaiABE40087; ABE40087; RPD_2859.
    GeneIDi4023357.
    KEGGirpd:RPD_2859.
    PATRICi23280771. VBIRhoPal120395_2951.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000283 Genomic DNA. Translation: ABE40087.1 .
    RefSeqi WP_011503264.1. NC_007958.1.
    YP_569988.1. NC_007958.1.

    3D structure databases

    ProteinModelPortali Q136A2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 316057.RPD_2859.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE40087 ; ABE40087 ; RPD_2859 .
    GeneIDi 4023357.
    KEGGi rpd:RPD_2859.
    PATRICi 23280771. VBIRhoPal120395_2951.

    Phylogenomic databases

    eggNOGi COG0820.
    HOGENOMi HOG000217991.
    KOi K06941.
    OMAi CAFACRF.
    OrthoDBi EOG6DJZ2N.

    Enzyme and pathway databases

    BioCyci RPAL316057:GHDC-2903-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR013785. Aldolase_TIM.
    IPR006638. Elp3/MiaB/NifB.
    IPR004383. rRNA_lsu_MTrfase_RlmN/Cfr.
    IPR007197. rSAM.
    [Graphical view ]
    PANTHERi PTHR30544. PTHR30544. 1 hit.
    Pfami PF04055. Radical_SAM. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006004. CHP00048. 1 hit.
    SMARTi SM00729. Elp3. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00048. TIGR00048. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BisB5.

    Entry informationi

    Entry nameiY2859_RHOPS
    AccessioniPrimary (citable) accession number: Q136A2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 2, 2008
    Last sequence update: October 31, 2006
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3