SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q13608

- PEX6_HUMAN

UniProt

Q13608 - PEX6_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Peroxisome assembly factor 2
Gene
PEX6, PXAAA1
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi470 – 4778ATP Reviewed prediction
Nucleotide bindingi744 – 7518ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB
  2. ATPase activity Source: UniProtKB
  3. ATPase activity, coupled Source: UniProtKB
  4. protein C-terminus binding Source: UniProtKB
  5. protein binding Source: UniProtKB
  6. protein complex binding Source: UniProtKB

GO - Biological processi

  1. ATP catabolic process Source: GOC
  2. peroxisome organization Source: UniProtKB
  3. protein import into peroxisome matrix, translocation Source: UniProtKB
  4. protein stabilization Source: UniProtKB
  5. protein targeting to peroxisome Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

Peroxisome biogenesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Protein family/group databases

TCDBi3.A.20.1.1. the peroxisomal protein importer (ppi) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisome assembly factor 2
Short name:
PAF-2
Alternative name(s):
Peroxin-6
Peroxisomal biogenesis factor 6
Peroxisomal-type ATPase 1
Gene namesi
Name:PEX6
Synonyms:PXAAA1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 6

Organism-specific databases

HGNCiHGNC:8859. PEX6.

Subcellular locationi

Cytoplasm. Peroxisome membrane
Note: Associated with peroxisomal membranes.

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
  2. cytosol Source: UniProtKB
  3. peroxisomal membrane Source: UniProtKB-SubCell
  4. peroxisome Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane, Peroxisome

Pathology & Biotechi

Involvement in diseasei

Peroxisome biogenesis disorder complementation group 4 (PBD-CG4) [MIM:614862]: A peroxisomal disorder arising from a failure of protein import into the peroxisomal membrane or matrix. The peroxisome biogenesis disorders (PBD group) are genetically heterogeneous with at least 14 distinct genetic groups as concluded from complementation studies. Include disorders are: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). ZWS, NALD and IRD are distinct from RCDP and constitute a clinical continuum of overlapping phenotypes known as the Zellweger spectrum (PBD-ZSS).
Note: The disease is caused by mutations affecting the gene represented in this entry.1 Publication
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti274 – 2741P → L in PBD-CG4. 1 Publication
VAR_058382
Natural varianti849 – 8491N → T in PBD-CG4. 1 Publication
VAR_058384
Natural varianti860 – 8601R → Q in PBD-CG4. 1 Publication
VAR_058385
Natural varianti860 – 8601R → W in PBD-CG4. 1 Publication
VAR_058386
Peroxisome biogenesis disorder 4A (PBD4A) [MIM:614862]: A fatal peroxisome biogenesis disorder belonging to the Zellweger disease spectrum and clinically characterized by severe neurologic dysfunction with profound psychomotor retardation, severe hypotonia and neonatal seizures, craniofacial abnormalities, liver dysfunction, and biochemically by the absence of peroxisomes. Additional features include cardiovascular and skeletal defects, renal cysts, ocular abnormalities, and hearing impairment. Most severely affected individuals with the classic form of the disease (classic Zellweger syndrome) die within the first year of life.
Note: The disease is caused by mutations affecting the gene represented in this entry.2 Publications
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti812 – 8121R → Q in PBD4A. 1 Publication
VAR_007918
Natural varianti812 – 8121R → W in PBD4A; atypical. 1 Publication
VAR_007919
Peroxisome biogenesis disorder 4B (PBD4B) [MIM:614863]: A peroxisome biogenesis disorder that includes neonatal adrenoleukodystrophy (NALD) and infantile Refsum disease (IRD), two milder manifestations of the Zellweger disease spectrum. The clinical course of patients with the NALD and IRD presentation is variable and may include developmental delay, hypotonia, liver dysfunction, sensorineural hearing loss, retinal dystrophy and vision impairment. Children with the NALD presentation may reach their teens, while patients with the IRD presentation may reach adulthood. The clinical conditions are often slowly progressive in particular with respect to loss of hearing and vision. The biochemical abnormalities include accumulation of phytanic acid, very long chain fatty acids (VLCFA), di- and trihydroxycholestanoic acid and pipecolic acid.
Note: The disease is caused by mutations affecting the gene represented in this entry.1 Publication

Keywords - Diseasei

Disease mutation, Peroxisome biogenesis disorder, Zellweger syndrome

Organism-specific databases

MIMi614862. phenotype.
614863. phenotype.
Orphaneti772. Infantile Refsum disease.
44. Neonatal adrenoleukodystrophy.
912. Zellweger syndrome.
PharmGKBiPA33201.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 980980Peroxisome assembly factor 2
PRO_0000084607Add
BLAST

Proteomic databases

MaxQBiQ13608.
PaxDbiQ13608.
PRIDEiQ13608.

PTM databases

PhosphoSiteiQ13608.

Expressioni

Gene expression databases

ArrayExpressiQ13608.
BgeeiQ13608.
CleanExiHS_PEX6.
GenevestigatoriQ13608.

Organism-specific databases

HPAiHPA025924.

Interactioni

Subunit structurei

Interacts directly with PEX26 and PEX1. Mediates the indirect interaction between PEX1 and PEX26. Interacts with ZFAND6.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
PEX1O439332EBI-988581,EBI-988601

Protein-protein interaction databases

BioGridi111213. 7 interactions.
IntActiQ13608. 6 interactions.
MINTiMINT-1183928.
STRINGi9606.ENSP00000303511.

Structurei

3D structure databases

ProteinModelPortaliQ13608.
SMRiQ13608. Positions 435-971.

Family & Domainsi

Sequence similaritiesi

Belongs to the AAA ATPase family.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0464.
HOGENOMiHOG000241031.
HOVERGENiHBG002311.
InParanoidiQ13608.
KOiK13339.
OMAiWHDVGGL.
OrthoDBiEOG74J979.
PhylomeDBiQ13608.
TreeFamiTF106428.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00004. AAA. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00674. AAA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q13608-1 [UniParc]FASTAAdd to Basket

« Hide

MALAVLRVLE PFPTETPPLA VLLPPGGPWP AAELGLVLAL RPAGESPAGP    50
ALLVAALEGP DAGTEEQGPG PPQLLVSRAL LRLLALGSGA WVRARAVRRP 100
PALGWALLGT SLGPGLGPRV GPLLVRRGET LPVPGPRVLE TRPALQGLLG 150
PGTRLAVTEL RGRARLCPES GDSSRPPPPP VVSSFAVSGT VRRLQGVLGG 200
TGDSLGVSRS CLRGLGLFQG EWVWVAQARE SSNTSQPHLA RVQVLEPRWD 250
LSDRLGPGSG PLGEPLADGL ALVPATLAFN LGCDPLEMGE LRIQRYLEGS 300
IAPEDKGSCS LLPGPPFARE LHIEIVSSPH YSTNGNYDGV LYRHFQIPRV 350
VQEGDVLCVP TIGQVEILEG SPEKLPRWRE MFFKVKKTVG EAPDGPASAY 400
LADTTHTSLY MVGSTLSPVP WLPSEESTLW SSLSPPGLEA LVSELCAVLK 450
PRLQPGGALL TGTSSVLLRG PPGCGKTTVV AAACSHLGLH LLKVPCSSLC 500
AESSGAVETK LQAIFSRARR CRPAVLLLTA VDLLGRDRDG LGEDARVMAV 550
LRHLLLNEDP LNSCPPLMVV ATTSRAQDLP ADVQTAFPHE LEVPALSEGQ 600
RLSILRALTA HLPLGQEVNL AQLARRCAGF VVGDLYALLT HSSRAACTRI 650
KNSGLAGGLT EEDEGELCAA GFPLLAEDFG QALEQLQTAH SQAVGAPKIP 700
SVSWHDVGGL QEVKKEILET IQLPLEHPEL LSLGLRRSGL LLHGPPGTGK 750
TLLAKAVATE CSLTFLSVKG PELINMYVGQ SEENVREVFA RARAAAPCII 800
FFDELDSLAP SRGRSGDSGG VMDRVVSQLL AELDGLHSTQ DVFVIGATNR 850
PDLLDPALLR PGRFDKLVFV GANEDRASQL RVLSAITRKF KLEPSVSLVN 900
VLDCCPPQLT GADLYSLCSD AMTAALKRRV HDLEEGLEPG SSALMLTMED 950
LLQAAARLQP SVSEQELLRY KRIQRKFAAC 980
Length:980
Mass (Da):104,061
Last modified:December 8, 2000 - v2
Checksum:i0EC1C2A75CE0038F
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti79 – 791A → P.1 Publication
Corresponds to variant rs61752141 [ dbSNP | Ensembl ].
VAR_058381
Natural varianti274 – 2741P → L in PBD-CG4. 1 Publication
VAR_058382
Natural varianti601 – 6011R → Q.1 Publication
Corresponds to variant rs34324426 [ dbSNP | Ensembl ].
VAR_058383
Natural varianti809 – 8091A → V.1 Publication
Corresponds to variant rs35830695 [ dbSNP | Ensembl ].
VAR_048114
Natural varianti812 – 8121R → Q in PBD4A. 1 Publication
VAR_007918
Natural varianti812 – 8121R → W in PBD4A; atypical. 1 Publication
VAR_007919
Natural varianti849 – 8491N → T in PBD-CG4. 1 Publication
VAR_058384
Natural varianti860 – 8601R → Q in PBD-CG4. 1 Publication
VAR_058385
Natural varianti860 – 8601R → W in PBD-CG4. 1 Publication
VAR_058386
Natural varianti882 – 8821V → I.1 Publication
Corresponds to variant rs2274516 [ dbSNP | Ensembl ].
VAR_048115
Natural varianti924 – 9241A → S.1 Publication
Corresponds to variant rs34551839 [ dbSNP | Ensembl ].
VAR_058387
Natural varianti939 – 9391P → Q.2 Publications
Corresponds to variant rs1129187 [ dbSNP | Ensembl ].
VAR_048116

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti77 – 771S → N in AAC50655. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U56602 Genomic DNA. Translation: AAC50655.1.
D83703 mRNA. Translation: BAA12069.1.
AF108098
, AF108095, AF108096, AF108097 Genomic DNA. Translation: AAF62564.1.
AB051076 mRNA. Translation: BAB83046.1.
AK314237 mRNA. Translation: BAG36906.1.
CH471081 Genomic DNA. Translation: EAX04125.1.
BC048331 mRNA. Translation: AAH48331.1.
CCDSiCCDS4877.1.
PIRiS71090.
RefSeqiNP_000278.3. NM_000287.3.
UniGeneiHs.656425.

Genome annotation databases

EnsembliENST00000304611; ENSP00000303511; ENSG00000124587.
GeneIDi5190.
KEGGihsa:5190.
UCSCiuc003otf.3. human.

Polymorphism databases

DMDMi12644408.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Web resourcesi

dbPEX, PEX Gene Database

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U56602 Genomic DNA. Translation: AAC50655.1 .
D83703 mRNA. Translation: BAA12069.1 .
AF108098
, AF108095 , AF108096 , AF108097 Genomic DNA. Translation: AAF62564.1 .
AB051076 mRNA. Translation: BAB83046.1 .
AK314237 mRNA. Translation: BAG36906.1 .
CH471081 Genomic DNA. Translation: EAX04125.1 .
BC048331 mRNA. Translation: AAH48331.1 .
CCDSi CCDS4877.1.
PIRi S71090.
RefSeqi NP_000278.3. NM_000287.3.
UniGenei Hs.656425.

3D structure databases

ProteinModelPortali Q13608.
SMRi Q13608. Positions 435-971.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 111213. 7 interactions.
IntActi Q13608. 6 interactions.
MINTi MINT-1183928.
STRINGi 9606.ENSP00000303511.

Protein family/group databases

TCDBi 3.A.20.1.1. the peroxisomal protein importer (ppi) family.

PTM databases

PhosphoSitei Q13608.

Polymorphism databases

DMDMi 12644408.

Proteomic databases

MaxQBi Q13608.
PaxDbi Q13608.
PRIDEi Q13608.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000304611 ; ENSP00000303511 ; ENSG00000124587 .
GeneIDi 5190.
KEGGi hsa:5190.
UCSCi uc003otf.3. human.

Organism-specific databases

CTDi 5190.
GeneCardsi GC06M042978.
GeneReviewsi PEX6.
HGNCi HGNC:8859. PEX6.
HPAi HPA025924.
MIMi 601498. gene.
614862. phenotype.
614863. phenotype.
neXtProti NX_Q13608.
Orphaneti 772. Infantile Refsum disease.
44. Neonatal adrenoleukodystrophy.
912. Zellweger syndrome.
PharmGKBi PA33201.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0464.
HOGENOMi HOG000241031.
HOVERGENi HBG002311.
InParanoidi Q13608.
KOi K13339.
OMAi WHDVGGL.
OrthoDBi EOG74J979.
PhylomeDBi Q13608.
TreeFami TF106428.

Miscellaneous databases

GeneWikii PEX6.
GenomeRNAii 5190.
NextBioi 20072.
PROi Q13608.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q13608.
Bgeei Q13608.
CleanExi HS_PEX6.
Genevestigatori Q13608.

Family and domain databases

Gene3Di 3.40.50.300. 2 hits.
InterProi IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00004. AAA. 2 hits.
[Graphical view ]
SMARTi SM00382. AAA. 2 hits.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 2 hits.
PROSITEi PS00674. AAA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor."
    Yahraus T., Braverman N., Dodt G., Kalish J.E., Morrell J.C., Moser H.W., Valle D., Gould S.J.
    EMBO J. 15:2914-2923(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], INVOLVEMENT IN PBD4A.
  2. "Human peroxisome assembly factor-2 (PAF-2): a gene responsible for group C peroxisome biogenesis disorder in humans."
    Fukuda S., Shimozawa N., Suzuki Y., Zhang Z., Tomatsu S., Tsukamoto T., Hashiguchi N., Osumi T., Masuno M., Imaizumi K., Kuroki Y., Fujiki Y., Orii T., Kondo N.
    Am. J. Hum. Genet. 59:1210-1220(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. "Genomic structure and identification of 11 novel mutations of the PEX6 'peroxisome assembly factor-2' gene in patients with peroxisome biogenesis disorders."
    Zhang Z., Suzuki Y., Shimozawa N., Fukuda S., Imamura A., Tsukamoto T., Osumi T., Fujiki Y., Orii T., Wanders R.J.A., Barth P.G., Moser H.W., Paton B.C., Besley G.T., Kondo N.
    Hum. Mutat. 13:487-496(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS PBD4A GLN-812 AND TRP-812.
  4. "The peroxin Pex6p gene is impaired in peroxisomal biogenesis disorders of complementation group 6."
    Matsumoto N., Tamura S., Moser A., Moser H.W., Braverman N., Suzuki Y., Shimozawa N., Kondo N., Fujiki Y.
    J. Hum. Genet. 46:273-277(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT GLN-939, INVOLVEMENT IN PBD4B.
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Synovium.
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Colon.
  8. "The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes."
    Matsumoto N., Tamura S., Fujiki Y.
    Nat. Cell Biol. 5:454-460(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH PEX26 AND PEX1.
  9. "AWP1/ZFAND6 functions in Pex5 export by interacting with cys-monoubiquitinated Pex5 and Pex6 AAA ATPase."
    Miyata N., Okumoto K., Mukai S., Noguchi M., Fujiki Y.
    Traffic 13:168-183(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH ZFAND6.
  10. "Identification of novel mutations and sequence variation in the Zellweger syndrome spectrum of peroxisome biogenesis disorders."
    Yik W.Y., Steinberg S.J., Moser A.B., Moser H.W., Hacia J.G.
    Hum. Mutat. 30:E467-E480(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS PBD-CG4 LEU-274; THR-849; GLN-860 AND TRP-860, VARIANTS PRO-79; GLN-601; VAL-809; ILE-882; SER-924 AND GLN-939.

Entry informationi

Entry nameiPEX6_HUMAN
AccessioniPrimary (citable) accession number: Q13608
Secondary accession number(s): Q5T8W1, Q8WYQ2, Q99476
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 8, 2000
Last modified: July 9, 2014
This is version 134 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi