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Q135M1

- Q135M1_RHOPS

UniProt

Q135M1 - Q135M1_RHOPS

Protein

Alanine racemase

Gene

RPD_2992

Organism
Rhodopseudomonas palustris (strain BisB5)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (31 Oct 2006)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei64 – 641Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei162 – 1621SubstrateUniRule annotation
    Active sitei283 – 2831Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei336 – 3361Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciRPAL316057:GHDC-3041-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:RPD_2992Imported
    OrganismiRhodopseudomonas palustris (strain BisB5)Imported
    Taxonomic identifieri316057 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
    ProteomesiUP000001818: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei64 – 641N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi316057.RPD_2992.

    Structurei

    3D structure databases

    ProteinModelPortaliQ135M1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031445.
    KOiK01775.
    OMAiANSAGIC.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q135M1-1 [UniParc]FASTAAdd to Basket

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    MNILPDPNAT VASLLTPEAA KAAALAAATA TAPGVLTVDL DAIVANWRKI    50
    EKTAVPAEAA AVVKGDAYGC GIGPVSKALA AAGCKTFFVA TLGEAGAVRA 100
    IAPDAVIYVL DGFFQTTGDE FARLNCRPVI GDLYELAEWD VYCRRTRWSG 150
    GAAIHIDTGM NRLGLTVAEA QGIVPRIAAG DHGITLVISH LAAAEALNHP 200
    MNARQVTAFR EIASLFTGVA ASLSASSGVF LGPQFAFDMV RPGAALYGIN 250
    PTPEADNPMK PVVDLKARIV QVRSVERGDS VGYGGTWTAR RPTRIAVLSA 300
    GYADGYFRAA GSNDGTRGAD VVIAGQRCPI AGRVSMDLLA VDVTDLPANA 350
    ARRGLMATLI GDGITVDELG HHFGTIGYEV LTSLGARYAR IYSGGDAKPE 400
    ETPAEQSGA 409
    Length:409
    Mass (Da):42,362
    Last modified:October 31, 2006 - v1
    Checksum:iE4B30512358D9895
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000283 Genomic DNA. Translation: ABE40218.1.
    RefSeqiWP_011503392.1. NC_007958.1.
    YP_570119.1. NC_007958.1.

    Genome annotation databases

    EnsemblBacteriaiABE40218; ABE40218; RPD_2992.
    GeneIDi4023495.
    KEGGirpd:RPD_2992.
    PATRICi23281049. VBIRhoPal120395_3087.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000283 Genomic DNA. Translation: ABE40218.1 .
    RefSeqi WP_011503392.1. NC_007958.1.
    YP_570119.1. NC_007958.1.

    3D structure databases

    ProteinModelPortali Q135M1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 316057.RPD_2992.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE40218 ; ABE40218 ; RPD_2992 .
    GeneIDi 4023495.
    KEGGi rpd:RPD_2992.
    PATRICi 23281049. VBIRhoPal120395_3087.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031445.
    KOi K01775.
    OMAi ANSAGIC.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci RPAL316057:GHDC-3041-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BisB5Imported.

    Entry informationi

    Entry nameiQ135M1_RHOPS
    AccessioniPrimary (citable) accession number: Q135M1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 31, 2006
    Last sequence update: October 31, 2006
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3