Unreviewed, UniProtKB/TrEMBL Q13518 (Q13518_HUMAN)

Names and origin

Protein names	Submitted name:     Protein kinase C-binding protein RACK8 EMBL AAC72246.1
Organism	Homo sapiens (Human) EMBL AAC72246.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	457 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 PDZ (DHR) domain.

Ontologies

Keywords
Molecular function	Kinase EMBL AAC72246.1 Transferase
Gene Ontology (GO)
Biological process	intracellular signaling cascade Inferred from electronic annotation. Source: InterPro multicellular organismal development Inferred from electronic annotation. Source: InterPro
Molecular function	kinase activity Inferred from electronic annotation. Source: UniProtKB-KW protein binding Inferred from electronic annotation. Source: Compara signal transducer activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAC72246.1

Sequences

	Sequence		Length	Mass (Da)
	Q13518-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 5021915C84024411	FASTA	457	49,036
	10 20 30 40 50 60 NSEKYNFLGI SIVGQSNERG DGGIYIGSIM KGGAVAADGR IEPGDMLLQV NEINFENMSN 70 80 90 100 110 120 DDAVRVLREI VHKPGPITLT VAKCWDPSPR GCFTLPRSEP IRPIDPAAWV SHTAAMTGTF 130 140 150 160 170 180 PAYGMSPSLS TITSTSSSIT SSIPDTERLD DFHLSIHSDM AAIVKAMASP ESGLEVRDRM 190 200 210 220 230 240 WLKITIPNAF IGSDVVDWLY HNVEGFTDRR EARKYASNLL KAGFIRHTVN KITFSEQCYY 250 260 270 280 290 300 IFGDFCGNMA NLSLHDHDGS SGASDQDTLA LLPHPGAAPW PMAFPYQYPP PPHPYNPHPG 310 320 330 340 350 360 FPELGYSYGG GSASSQHSEG SRSSGSNRSG SDRRKEKDPK AGDSKSGGSG SESDHTTRSS 370 380 390 400 410 420 LRGPRERAPS ERSGPAASEH SHRSHHSLAS SLRSHHTHPS YGPPGVPPLY GPPMLMMPPP 430 440 450 PAAMGPPGAP PGRDPGLSAP GTDRQQTVLP HGHGKPQ

References

[1]	"Protein Kinase C-Binding Protein." Kuroda S., Tokunaga C., Kiyohara Y., Konishi H., Kikkawa U. Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Hippocampus EMBL AAC72246.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U48252 mRNA. Translation: AAC72246.1.
IPI	IPI00383832.
UniGene	Hs.388116
3D structure databases
HSSP	HSSP built from PDB template 1L6O based on UniProtKB P51142.
SMR	Q13518. Positions 1-83, 154-244.
ModBase	Search...
Protein-protein interaction databases
STRING	Q13518.
Genome annotation databases
Ensembl	ENST00000313143; ENSP00000316054; ENSG00000161202; Homo sapiens. [Genome view] ENST00000415612; ENSP00000392792; ENSG00000161202; Homo sapiens. [Genome view]
Organism-specific databases
HGNC	HGNC:3087. DVL3.
Phylogenomic databases
HOVERGEN	Q13518.
Gene expression databases
ArrayExpress	Q13518.
Bgee	Q13518.
Family and domain databases
InterPro	IPR000591. DEP_dom. IPR008339. Dishevell. IPR008342. Dishevelled_3_C. IPR015506. Dsh. IPR001478. PDZ/DHR/GLGF. IPR011991. WHTH_trsnscrt_rep_DNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
PANTHER	PTHR10878. Dsh. 1 hit.
Pfam	PF00610. DEP. 1 hit. PF00595. PDZ. 1 hit. [Graphical view]
PRINTS	PR01760. DISHEVELLED. PR01763. DISHEVELLED3.
SMART	SM00049. DEP. 1 hit. SM00228. PDZ. 1 hit. [Graphical view]
PROSITE	PS50186. DEP. 1 hit. PS50106. PDZ. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q13518_HUMAN

Accession

Primary (citable) accession number: Q13518

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	February 9, 2010
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.