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Protein

MDS1 and EVI1 complex locus protein MDS1

Gene

MECOM

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • transcription factor activity, sequence-specific DNA binding Source: ProtInc
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
MDS1 and EVI1 complex locus protein MDS1
Alternative name(s):
Myelodysplasia syndrome 1 protein
Myelodysplasia syndrome-associated protein 1
Gene namesi
Name:MECOM
Synonyms:MDS1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:3498. MECOM.

Pathology & Biotechi

Involvement in diseasei

A chromosomal aberration involving MDS1 is found in a form of acute myeloid leukemia (AML). Translocation t(3;21) with AML1.

Organism-specific databases

MalaCardsiMECOM.
PharmGKBiPA27912.
PA30722.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 169169MDS1 and EVI1 complex locus protein MDS1PRO_0000096338Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Isoform 4 (identifier: Q03112-4)