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Q13306

- Q13306_HUMAN

UniProt

Q13306 - Q13306_HUMAN

Protein
Submitted name:

Thyroid transcription factor-1

Gene

TTF-1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Source: Ensembl
    2. sequence-specific DNA binding Source: Ensembl
    3. transcription regulatory region DNA binding Source: Ensembl

    GO - Biological processi

    1. anatomical structure formation involved in morphogenesis Source: Ensembl
    2. axon guidance Source: Ensembl
    3. cerebral cortex cell migration Source: Ensembl
    4. cerebral cortex GABAergic interneuron differentiation Source: Ensembl
    5. Clara cell differentiation Source: Ensembl
    6. developmental induction Source: Ensembl
    7. endoderm development Source: Ensembl
    8. forebrain dorsal/ventral pattern formation Source: Ensembl
    9. forebrain neuron fate commitment Source: Ensembl
    10. globus pallidus development Source: Ensembl
    11. hippocampus development Source: Ensembl
    12. Leydig cell differentiation Source: Ensembl
    13. locomotory behavior Source: Ensembl
    14. lung saccule development Source: Ensembl
    15. menarche Source: Ensembl
    16. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
    17. neuron migration Source: Ensembl
    18. oligodendrocyte differentiation Source: Ensembl
    19. organ morphogenesis Source: Ensembl
    20. phospholipid metabolic process Source: Ensembl
    21. pituitary gland development Source: Ensembl
    22. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    23. thyroid gland development Source: Ensembl
    24. Type II pneumocyte differentiation Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Thyroid transcription factor-1Imported
    Gene namesi
    Name:TTF-1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: Ensembl
    2. transcription factor complex Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ13306.

    Expressioni

    Gene expression databases

    ArrayExpressiQ13306.
    BgeeiQ13306.

    Sequencei

    Sequence statusi: Fragment.

    Q13306-1 [UniParc]FASTAAdd to Basket

    « Hide

    MWSGGSGKAR GWEAAAGGRS SPGRLSRRRI MSMSPKHTTP FSVSDILSPL   50
    EESYKKVGME GGGLGAPLAA Y 71
    Length:71
    Mass (Da):7,425
    Last modified:November 1, 1996 - v1
    Checksum:i7ABFD04CD963A711
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei71 – 711Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U33627 Genomic DNA. Translation: AAA83233.1.
    UniGeneiHs.94367.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U33627 Genomic DNA. Translation: AAA83233.1 .
    UniGenei Hs.94367.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q13306.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Gene expression databases

    ArrayExpressi Q13306.
    Bgeei Q13306.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Characterization of TTF-1 transcripts in human lung identifies an additional exon."
      Hamdan H., Liu H., Jones C., deLemos R., Minoo P.
      Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ13306_HUMAN
    AccessioniPrimary (citable) accession number: Q13306
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.