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Q13306

- Q13306_HUMAN

UniProt

Q13306 - Q13306_HUMAN

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Protein
Submitted name:

Thyroid transcription factor-1

Gene

TTF-1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. core promoter binding Source: Ensembl
  2. RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Source: Ensembl
  3. sequence-specific DNA binding Source: Ensembl

GO - Biological processi

  1. anatomical structure formation involved in morphogenesis Source: Ensembl
  2. axon guidance Source: Ensembl
  3. cerebral cortex cell migration Source: Ensembl
  4. cerebral cortex GABAergic interneuron differentiation Source: Ensembl
  5. Clara cell differentiation Source: Ensembl
  6. developmental induction Source: Ensembl
  7. endoderm development Source: Ensembl
  8. forebrain dorsal/ventral pattern formation Source: Ensembl
  9. forebrain neuron fate commitment Source: Ensembl
  10. globus pallidus development Source: Ensembl
  11. hippocampus development Source: Ensembl
  12. Leydig cell differentiation Source: Ensembl
  13. locomotory behavior Source: Ensembl
  14. lung saccule development Source: Ensembl
  15. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
  16. neuron migration Source: Ensembl
  17. oligodendrocyte differentiation Source: Ensembl
  18. organ morphogenesis Source: Ensembl
  19. phospholipid metabolic process Source: Ensembl
  20. pituitary gland development Source: Ensembl
  21. positive regulation of circadian rhythm Source: Ensembl
  22. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  23. thyroid gland development Source: Ensembl
  24. Type II pneumocyte differentiation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Thyroid transcription factor-1Imported
Gene namesi
Name:TTF-1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: Ensembl
  2. transcription factor complex Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ13306.

Expressioni

Gene expression databases

BgeeiQ13306.
ExpressionAtlasiQ13306. baseline and differential.

Sequencei

Sequence statusi: Fragment.

Q13306-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MWSGGSGKAR GWEAAAGGRS SPGRLSRRRI MSMSPKHTTP FSVSDILSPL
60 70
EESYKKVGME GGGLGAPLAA Y
Length:71
Mass (Da):7,425
Last modified:November 1, 1996 - v1
Checksum:i7ABFD04CD963A711
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei71 – 711Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33627 Genomic DNA. Translation: AAA83233.1.
UniGeneiHs.94367.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33627 Genomic DNA. Translation: AAA83233.1 .
UniGenei Hs.94367.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q13306.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Gene expression databases

Bgeei Q13306.
ExpressionAtlasi Q13306. baseline and differential.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Characterization of TTF-1 transcripts in human lung identifies an additional exon."
    Hamdan H., Liu H., Jones C., deLemos R., Minoo P.
    Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ13306_HUMAN
AccessioniPrimary (citable) accession number: Q13306
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 26, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.