ID   SG2A2_HUMAN             Reviewed;          93 AA.
AC   Q13296; A1A522; Q86WH8;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   11-NOV-2015, entry version 117.
DE   RecName: Full=Mammaglobin-A;
DE   AltName: Full=Mammaglobin-1;
DE   AltName: Full=Secretoglobin family 2A member 2;
DE   Flags: Precursor;
GN   Name=SCGB2A2; Synonyms=MGB1, UGB2;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RC   TISSUE=Mammary gland;
RX   PubMed=8631025;
RA   Watson M.A., Fleming T.P.;
RT   "Mammaglobin, a mammary-specific member of the uteroglobin gene
RT   family, is overexpressed in human breast cancer.";
RL   Cancer Res. 56:860-865(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1).
RX   PubMed=9488047; DOI=10.1038/sj.onc.1201597;
RA   Watson M.A., Darrow C., Zimonjic D.B., Popescu N.C., Fleming T.;
RT   "Structure and transcriptional regulation of the human mammaglobin
RT   gene, a breast cancer associated member of the uteroglobin gene family
RT   localized to chromosome 11q13.";
RL   Oncogene 16:817-824(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
RA   Zhao L., Nan K.;
RT   "An alternative splicing isoform of mammaglobin.";
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- INTERACTION:
CC       P50552:VASP; NbExp=3; IntAct=EBI-9058786, EBI-748201;
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q13296-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q13296-2; Sequence=VSP_009122;
CC   -!- TISSUE SPECIFICITY: Mammary gland specific. Over-expressed in
CC       breast cancer.
CC   -!- SIMILARITY: Belongs to the secretoglobin family. Lipophilin
CC       subfamily. {ECO:0000305}.
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DR   EMBL; U33147; AAC50375.1; -; mRNA.
DR   EMBL; AF015224; AAC39608.1; -; Genomic_DNA.
DR   EMBL; AY217100; AAO60111.1; -; mRNA.
DR   EMBL; BC128252; AAI28253.1; -; mRNA.
DR   EMBL; BC128402; AAI28403.1; -; mRNA.
DR   CCDS; CCDS8018.1; -. [Q13296-1]
DR   RefSeq; NP_002402.1; NM_002411.3. [Q13296-1]
DR   UniGene; Hs.46452; -.
DR   ProteinModelPortal; Q13296; -.
DR   SMR; Q13296; 21-91.
DR   BioGrid; 110406; 74.
DR   IntAct; Q13296; 4.
DR   STRING; 9606.ENSP00000227918; -.
DR   DMDM; 2833243; -.
DR   PaxDb; Q13296; -.
DR   PRIDE; Q13296; -.
DR   DNASU; 4250; -.
DR   Ensembl; ENST00000227918; ENSP00000227918; ENSG00000110484. [Q13296-1]
DR   GeneID; 4250; -.
DR   KEGG; hsa:4250; -.
DR   UCSC; uc001ntc.3; human. [Q13296-1]
DR   CTD; 4250; -.
DR   GeneCards; SCGB2A2; -.
DR   HGNC; HGNC:7050; SCGB2A2.
DR   HPA; CAB026270; -.
DR   HPA; HPA036184; -.
DR   MIM; 605562; gene.
DR   neXtProt; NX_Q13296; -.
DR   PharmGKB; PA34993; -.
DR   eggNOG; ENOG410JEU0; Eukaryota.
DR   eggNOG; ENOG4111A32; LUCA.
DR   GeneTree; ENSGT00390000013802; -.
DR   HOGENOM; HOG000294150; -.
DR   HOVERGEN; HBG005021; -.
DR   InParanoid; Q13296; -.
DR   OMA; QLIYDSS; -.
DR   OrthoDB; EOG79W97Q; -.
DR   PhylomeDB; Q13296; -.
DR   TreeFam; TF338521; -.
DR   GeneWiki; Mammaglobin-A; -.
DR   GenomeRNAi; 4250; -.
DR   NextBio; 16755; -.
DR   PRO; PR:Q13296; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; Q13296; -.
DR   CleanEx; HS_SCGB2A2; -.
DR   ExpressionAtlas; Q13296; baseline and differential.
DR   Genevisible; Q13296; HS.
DR   InterPro; IPR016126; Secretoglobin.
DR   Pfam; PF01099; Uteroglobin; 1.
DR   SMART; SM00096; UTG; 1.
DR   SUPFAM; SSF48201; SSF48201; 1.
DR   PROSITE; PS51311; SCGB; 1.
PE   1: Evidence at protein level;
KW   Alternative splicing; Complete proteome; Glycoprotein;
KW   Reference proteome; Signal.
FT   SIGNAL        1     18       {ECO:0000255}.
FT   CHAIN        19     93       Mammaglobin-A.
FT                                /FTId=PRO_0000036372.
FT   CARBOHYD     53     53       N-linked (GlcNAc...). {ECO:0000255}.
FT   CARBOHYD     68     68       N-linked (GlcNAc...). {ECO:0000255}.
FT   VAR_SEQ      79     81       Missing (in isoform 2).
FT                                {ECO:0000303|Ref.3}.
FT                                /FTId=VSP_009122.
SQ   SEQUENCE   93 AA;  10499 MW;  2896E8C43BF053E2 CRC64;
     MKLLMVLMLA ALSQHCYAGS GCPLLENVIS KTINPQVSKT EYKELLQEFI DDNATTNAID
     ELKECFLNQT DETLSNVEVF MQLIYDSSLC DLF
//