Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Hepatocyte growth factor-like protein homolog

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionSerine protease homologUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Hepatocyte growth factor-like protein homologImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi166 ↔ 243PROSITE-ProRule annotation
Disulfide bondi187 ↔ 226PROSITE-ProRule annotation
Disulfide bondi215 ↔ 238PROSITE-ProRule annotation
Disulfide bondi279 ↔ 318PROSITE-ProRule annotation
Disulfide bondi307 ↔ 330PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PaxDbiQ13208.
PeptideAtlasiQ13208.
PRIDEiQ13208.

Structurei

3D structure databases

ProteinModelPortaliQ13208.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 80AppleInterPro annotationAdd BLAST76
Domaini84 – 161KringleInterPro annotationAdd BLAST78
Domaini165 – 243KringleInterPro annotationAdd BLAST79
Domaini257 – 336KringleInterPro annotationAdd BLAST80
Domaini344 – 423KringleInterPro annotationAdd BLAST80
Domaini459 – 567Peptidase S1InterPro annotationAdd BLAST109

Sequence similaritiesi

Belongs to the peptidase S1 family. Plasminogen subfamily.UniRule annotation

Keywords - Domaini

KringlePROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IDXR. Eukaryota.
COG5640. LUCA.
HOVERGENiHBG004381.

Family and domain databases

InterProiView protein in InterPro
IPR024174. HGF-like.
IPR000001. Kringle.
IPR013806. Kringle-like.
IPR018056. Kringle_CS.
IPR003609. Pan_app.
IPR009003. Peptidase_S1_PA.
IPR001254. Trypsin_dom.
PfamiView protein in Pfam
PF00051. Kringle. 4 hits.
PF00024. PAN_1. 1 hit.
PF00089. Trypsin. 1 hit.
PIRSFiPIRSF001152. HGF_MST1. 1 hit.
SMARTiView protein in SMART
SM00130. KR. 4 hits.
SM00473. PAN_AP. 1 hit.
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF57440. SSF57440. 4 hits.
PROSITEiView protein in PROSITE
PS00021. KRINGLE_1. 2 hits.
PS50070. KRINGLE_2. 4 hits.
PS50948. PAN. 1 hit.
PS50240. TRYPSIN_DOM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q13208-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSRCSGAQS YLLHAVVPGP WQEDVADAEE CAGRCGLLMD CWAFHYNVSS
60 70 80 90 100
HGCQLLPWTQ HSPHSRLRHS GRCDLFQKKD YIRTCIMNNG VGYRDTMATT
110 120 130 140 150
VGGLSCQAWS HKFPNDHQYM PTLRNGLEEN FCRNPDGDPG GPWCHTTDPA
160 170 180 190 200
VRFQSCGIKS CLVAACVWCN GEEYRGAVDR TESGRECQRW DLQHPHQHPF
210 220 230 240 250
EPGKFLDQGL DDNYCRSPDG SQRPWCYTTD PQIEREFCDL PRCGSEAQPR
260 270 280 290 300
QEATSVSCFR GKGEGYRGTA NTTTAGVPCQ RWDAQIPHQH RFTPEKYACK
310 320 330 340 350
DLRENFCRNP DGSEAPWCFT LRPGTRVGFC YQIRRCTDDV RPQDCYHGAG
360 370 380 390 400
EQYRGTVSKT RKGVQCQRWS AETPHKPQFT FTSEPHAQLE ENFCQNPDGD
410 420 430 440 450
SHGPWCYTMD PRTPFDYCAL RRCADDQPPS ILDPPDQVQF EKCGKRVDRL
460 470 480 490 500
DQRRSKLRVA GGHPGNSPWT VSLGNRQGQH FCGGSLVKEQ WILTARQCFS
510 520 530 540 550
SCHMPLTGYE VWLGTLFQNP QHGEPGLQRV PVAKMLCGPS GSQLVLLKLE
560
RSVTLNQRVA LICLPPE
Length:567
Mass (Da):64,117
Last modified:November 1, 1996 - v1
Checksum:i3FC38B07F1645810
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28054 Genomic DNA. Translation: AAC63092.1.
UniGeneiHs.349110.
Hs.512587.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ13208_HUMAN
AccessioniPrimary (citable) accession number: Q13208
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 5, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation