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Protein
Submitted name:

Hepatocyte growth factor-like protein homolog

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Serine protease homologUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Hepatocyte growth factor-like protein homologImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiQ13208.
PeptideAtlasiQ13208.
PRIDEiQ13208.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000414287.

Structurei

3D structure databases

ProteinModelPortaliQ13208.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 8076AppleInterPro annotationAdd
BLAST
Domaini84 – 16178KringleInterPro annotationAdd
BLAST
Domaini165 – 24379KringleInterPro annotationAdd
BLAST
Domaini257 – 33680KringleInterPro annotationAdd
BLAST
Domaini344 – 42380KringleInterPro annotationAdd
BLAST
Domaini459 – 567109Peptidase S1InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase S1 family. Plasminogen subfamily.UniRule annotation
Contains 1 peptidase S1 domain.UniRule annotation

Keywords - Domaini

KringleSAAS annotation

Phylogenomic databases

eggNOGiENOG410IDXR. Eukaryota.
COG5640. LUCA.
HOVERGENiHBG004381.

Family and domain databases

InterProiIPR024174. HGF-like.
IPR000001. Kringle.
IPR013806. Kringle-like.
IPR018056. Kringle_CS.
IPR003609. Pan_app.
IPR009003. Peptidase_S1_PA.
IPR001254. Trypsin_dom.
[Graphical view]
PfamiPF00051. Kringle. 4 hits.
PF00024. PAN_1. 1 hit.
PF00089. Trypsin. 1 hit.
[Graphical view]
PIRSFiPIRSF001152. HGF_MST1. 1 hit.
SMARTiSM00130. KR. 4 hits.
SM00473. PAN_AP. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF57440. SSF57440. 4 hits.
PROSITEiPS00021. KRINGLE_1. 3 hits.
PS50070. KRINGLE_2. 4 hits.
PS50948. PAN. 1 hit.
PS50240. TRYPSIN_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q13208-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSRCSGAQS YLLHAVVPGP WQEDVADAEE CAGRCGLLMD CWAFHYNVSS
60 70 80 90 100
HGCQLLPWTQ HSPHSRLRHS GRCDLFQKKD YIRTCIMNNG VGYRDTMATT
110 120 130 140 150
VGGLSCQAWS HKFPNDHQYM PTLRNGLEEN FCRNPDGDPG GPWCHTTDPA
160 170 180 190 200
VRFQSCGIKS CLVAACVWCN GEEYRGAVDR TESGRECQRW DLQHPHQHPF
210 220 230 240 250
EPGKFLDQGL DDNYCRSPDG SQRPWCYTTD PQIEREFCDL PRCGSEAQPR
260 270 280 290 300
QEATSVSCFR GKGEGYRGTA NTTTAGVPCQ RWDAQIPHQH RFTPEKYACK
310 320 330 340 350
DLRENFCRNP DGSEAPWCFT LRPGTRVGFC YQIRRCTDDV RPQDCYHGAG
360 370 380 390 400
EQYRGTVSKT RKGVQCQRWS AETPHKPQFT FTSEPHAQLE ENFCQNPDGD
410 420 430 440 450
SHGPWCYTMD PRTPFDYCAL RRCADDQPPS ILDPPDQVQF EKCGKRVDRL
460 470 480 490 500
DQRRSKLRVA GGHPGNSPWT VSLGNRQGQH FCGGSLVKEQ WILTARQCFS
510 520 530 540 550
SCHMPLTGYE VWLGTLFQNP QHGEPGLQRV PVAKMLCGPS GSQLVLLKLE
560
RSVTLNQRVA LICLPPE
Length:567
Mass (Da):64,117
Last modified:November 1, 1996 - v1
Checksum:i3FC38B07F1645810
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28054 Genomic DNA. Translation: AAC63092.1.
UniGeneiHs.349110.
Hs.512587.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28054 Genomic DNA. Translation: AAC63092.1.
UniGeneiHs.349110.
Hs.512587.

3D structure databases

ProteinModelPortaliQ13208.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000414287.

Proteomic databases

PaxDbiQ13208.
PeptideAtlasiQ13208.
PRIDEiQ13208.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

H-InvDBHIX0023583.
HIX0028912.

Phylogenomic databases

eggNOGiENOG410IDXR. Eukaryota.
COG5640. LUCA.
HOVERGENiHBG004381.

Family and domain databases

InterProiIPR024174. HGF-like.
IPR000001. Kringle.
IPR013806. Kringle-like.
IPR018056. Kringle_CS.
IPR003609. Pan_app.
IPR009003. Peptidase_S1_PA.
IPR001254. Trypsin_dom.
[Graphical view]
PfamiPF00051. Kringle. 4 hits.
PF00024. PAN_1. 1 hit.
PF00089. Trypsin. 1 hit.
[Graphical view]
PIRSFiPIRSF001152. HGF_MST1. 1 hit.
SMARTiSM00130. KR. 4 hits.
SM00473. PAN_AP. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF57440. SSF57440. 4 hits.
PROSITEiPS00021. KRINGLE_1. 3 hits.
PS50070. KRINGLE_2. 4 hits.
PS50948. PAN. 1 hit.
PS50240. TRYPSIN_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ13208_HUMAN
AccessioniPrimary (citable) accession number: Q13208
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.