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Q13118

- KLF10_HUMAN

UniProt

Q13118 - KLF10_HUMAN

Protein

Krueppel-like factor 10

Gene

KLF10

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • History
      Entry version 143 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Transcriptional repressor involved in the regulation of cell growth. Inhibits cell growth. Binds to the consensus sequence 5'-GGTGTG-3'.1 Publication

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri369 – 39325C2H2-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri399 – 42325C2H2-type 2PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri429 – 45123C2H2-type 3PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. protein binding Source: IntAct
    4. sequence-specific DNA binding transcription factor activity Source: ProtInc

    GO - Biological processi

    1. bone mineralization Source: Ensembl
    2. cell-cell signaling Source: ProtInc
    3. cell proliferation Source: ProtInc
    4. cellular response to peptide Source: Ensembl
    5. negative regulation of cell proliferation Source: ProtInc
    6. negative regulation of transcription from RNA polymerase II promoter Source: ProtInc
    7. positive regulation of osteoclast differentiation Source: Ensembl
    8. skeletal system development Source: ProtInc
    9. somatic stem cell maintenance Source: Ensembl
    10. transcription, DNA-templated Source: UniProtKB-KW
    11. transforming growth factor beta receptor signaling pathway Source: ProtInc

    Keywords - Molecular functioni

    Repressor

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Krueppel-like factor 10
    Alternative name(s):
    EGR-alpha
    Transforming growth factor-beta-inducible early growth response protein 1
    Short name:
    TGFB-inducible early growth response protein 1
    Short name:
    TIEG-1
    Gene namesi
    Name:KLF10
    Synonyms:TIEG, TIEG1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 8

    Organism-specific databases

    HGNCiHGNC:11810. KLF10.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: ProtInc

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA36517.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 480480Krueppel-like factor 10PRO_0000047177Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei249 – 2491Phosphoserine1 Publication

    Post-translational modificationi

    Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.Curated

    Keywords - PTMi

    Phosphoprotein, Ubl conjugation

    Proteomic databases

    PaxDbiQ13118.
    PRIDEiQ13118.

    PTM databases

    PhosphoSiteiQ13118.

    Expressioni

    Inductioni

    By TGFB1.

    Gene expression databases

    BgeeiQ13118.
    CleanExiHS_KLF10.
    GenevestigatoriQ13118.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    SP1P080472EBI-1389509,EBI-298336

    Protein-protein interaction databases

    BioGridi112927. 17 interactions.
    IntActiQ13118. 14 interactions.
    MINTiMINT-144333.
    STRINGi9606.ENSP00000285407.

    Structurei

    Secondary structure

    1
    480
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Turni374 – 3763
    Beta strandi379 – 3824
    Helixi383 – 39311
    Beta strandi394 – 3963
    Beta strandi398 – 4003
    Beta strandi409 – 4124
    Helixi413 – 4197
    Turni420 – 4223

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2EPANMR-A359-423[»]
    ProteinModelPortaliQ13118.
    SMRiQ13118. Positions 353-452.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ13118.

    Family & Domainsi

    Sequence similaritiesi

    Contains 3 C2H2-type zinc fingers.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri369 – 39325C2H2-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri399 – 42325C2H2-type 2PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri429 – 45123C2H2-type 3PROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiCOG5048.
    HOGENOMiHOG000059558.
    HOVERGENiHBG052264.
    InParanoidiQ13118.
    KOiK09209.
    OMAiVQNPKPP.
    OrthoDBiEOG7FJH0Q.
    PhylomeDBiQ13118.
    TreeFamiTF315506.

    Family and domain databases

    Gene3Di3.30.160.60. 3 hits.
    InterProiIPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    SMARTiSM00355. ZnF_C2H2. 3 hits.
    [Graphical view]
    PROSITEiPS00028. ZINC_FINGER_C2H2_1. 3 hits.
    PS50157. ZINC_FINGER_C2H2_2. 3 hits.
    [Graphical view]

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q13118-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MLNFGASLQQ TAEERMEMIS ERPKESMYSW NKTAEKSDFE AVEALMSMSC    50
    SWKSDFKKYV ENRPVTPVSD LSEEENLLPG TPDFHTIPAF CLTPPYSPSD 100
    FEPSQVSNLM APAPSTVHFK SLSDTAKPHI AAPFKEEEKS PVSAPKLPKA 150
    QATSVIRHTA DAQLCNHQTC PMKAASILNY QNNSFRRRTH LNVEAARKNI 200
    PCAAVSPNRS KCERNTVADV DEKASAALYD FSVPSSETVI CRSQPAPVSP 250
    QQKSVLVSPP AVSAGGVPPM PVICQMVPLP ANNPVVTTVV PSTPPSQPPA 300
    VCPPVVFMGT QVPKGAVMFV VPQPVVQSSK PPVVSPNGTR LSPIAPAPGF 350
    SPSAAKVTPQ IDSSRIRSHI CSHPGCGKTY FKSSHLKAHT RTHTGEKPFS 400
    CSWKGCERRF ARSDELSRHR RTHTGEKKFA CPMCDRRFMR SDHLTKHARR 450
    HLSAKKLPNW QMEVSKLNDI ALPPTPAPTQ 480
    Length:480
    Mass (Da):52,555
    Last modified:November 1, 1996 - v1
    Checksum:i78B1EBB0DB97579D
    GO
    Isoform 2 (identifier: Q13118-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-12: MLNFGASLQQTA → M

    Note: No experimental confirmation available.

    Show »
    Length:469
    Mass (Da):51,424
    Checksum:iE825F2BA7D5F74BD
    GO
    Isoform 3 (identifier: Q13118-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-12: MLNFGASLQQTA → M
         91-102: CLTPPYSPSDFE → QQKSLLRLIHQG
         103-480: Missing.

    Show »
    Length:91
    Mass (Da):10,600
    Checksum:i333972E3AEDCCBCD
    GO
    Isoform 4 (identifier: Q13118-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-12: MLNFGASLQQTA → M
         91-134: CLTPPYSPSD...TAKPHIAAPF → EKSLSAVAGK...LRAPCVTGGS
         135-480: Missing.

    Show »
    Length:123
    Mass (Da):13,702
    Checksum:i23B95EC936A769C1
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti249 – 2491S → F.
    Corresponds to variant rs4734653 [ dbSNP | Ensembl ].
    VAR_052716

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 1212MLNFG…LQQTA → M in isoform 2, isoform 3 and isoform 4. 4 PublicationsVSP_042653Add
    BLAST
    Alternative sequencei91 – 13444CLTPP…IAAPF → EKSLSAVAGKVVKGGLPVLM NCPDTGEPTRVRRNLRAPCV TGGS in isoform 4. 1 PublicationVSP_047482Add
    BLAST
    Alternative sequencei91 – 10212CLTPP…PSDFE → QQKSLLRLIHQG in isoform 3. 1 PublicationVSP_047483Add
    BLAST
    Alternative sequencei103 – 480378Missing in isoform 3. 1 PublicationVSP_047484Add
    BLAST
    Alternative sequencei135 – 480346Missing in isoform 4. 1 PublicationVSP_047485Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S81439 mRNA. Translation: AAB36088.1.
    U21847 mRNA. Translation: AAC50340.1.
    AF050110 Genomic DNA. Translation: AAC34293.1.
    AF050110 Genomic DNA. Translation: AAC34294.1.
    HF546210 mRNA. Translation: CCO02796.1.
    HF546211 mRNA. Translation: CCO02797.1.
    BT006634 mRNA. Translation: AAP35280.1.
    AK312894 mRNA. Translation: BAG35741.1.
    AP002851 Genomic DNA. No translation available.
    CH471060 Genomic DNA. Translation: EAW91850.1.
    BC011538 mRNA. Translation: AAH11538.1.
    BC095399 mRNA. Translation: AAH95399.1.
    CCDSiCCDS47905.1. [Q13118-2]
    CCDS6294.1. [Q13118-1]
    RefSeqiNP_001027453.1. NM_001032282.3. [Q13118-2]
    NP_005646.1. NM_005655.3. [Q13118-1]
    UniGeneiHs.435001.

    Genome annotation databases

    EnsembliENST00000285407; ENSP00000285407; ENSG00000155090. [Q13118-1]
    ENST00000395884; ENSP00000379222; ENSG00000155090. [Q13118-2]
    GeneIDi7071.
    KEGGihsa:7071.
    UCSCiuc011lhj.1. human. [Q13118-2]
    uc011lhk.1. human. [Q13118-1]

    Polymorphism databases

    DMDMi11387050.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S81439 mRNA. Translation: AAB36088.1 .
    U21847 mRNA. Translation: AAC50340.1 .
    AF050110 Genomic DNA. Translation: AAC34293.1 .
    AF050110 Genomic DNA. Translation: AAC34294.1 .
    HF546210 mRNA. Translation: CCO02796.1 .
    HF546211 mRNA. Translation: CCO02797.1 .
    BT006634 mRNA. Translation: AAP35280.1 .
    AK312894 mRNA. Translation: BAG35741.1 .
    AP002851 Genomic DNA. No translation available.
    CH471060 Genomic DNA. Translation: EAW91850.1 .
    BC011538 mRNA. Translation: AAH11538.1 .
    BC095399 mRNA. Translation: AAH95399.1 .
    CCDSi CCDS47905.1. [Q13118-2 ]
    CCDS6294.1. [Q13118-1 ]
    RefSeqi NP_001027453.1. NM_001032282.3. [Q13118-2 ]
    NP_005646.1. NM_005655.3. [Q13118-1 ]
    UniGenei Hs.435001.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2EPA NMR - A 359-423 [» ]
    ProteinModelPortali Q13118.
    SMRi Q13118. Positions 353-452.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 112927. 17 interactions.
    IntActi Q13118. 14 interactions.
    MINTi MINT-144333.
    STRINGi 9606.ENSP00000285407.

    PTM databases

    PhosphoSitei Q13118.

    Polymorphism databases

    DMDMi 11387050.

    Proteomic databases

    PaxDbi Q13118.
    PRIDEi Q13118.

    Protocols and materials databases

    DNASUi 7071.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000285407 ; ENSP00000285407 ; ENSG00000155090 . [Q13118-1 ]
    ENST00000395884 ; ENSP00000379222 ; ENSG00000155090 . [Q13118-2 ]
    GeneIDi 7071.
    KEGGi hsa:7071.
    UCSCi uc011lhj.1. human. [Q13118-2 ]
    uc011lhk.1. human. [Q13118-1 ]

    Organism-specific databases

    CTDi 7071.
    GeneCardsi GC08M103661.
    HGNCi HGNC:11810. KLF10.
    MIMi 601878. gene.
    neXtProti NX_Q13118.
    PharmGKBi PA36517.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG5048.
    HOGENOMi HOG000059558.
    HOVERGENi HBG052264.
    InParanoidi Q13118.
    KOi K09209.
    OMAi VQNPKPP.
    OrthoDBi EOG7FJH0Q.
    PhylomeDBi Q13118.
    TreeFami TF315506.

    Miscellaneous databases

    EvolutionaryTracei Q13118.
    GeneWikii KLF10.
    GenomeRNAii 7071.
    NextBioi 27649.
    PROi Q13118.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q13118.
    CleanExi HS_KLF10.
    Genevestigatori Q13118.

    Family and domain databases

    Gene3Di 3.30.160.60. 3 hits.
    InterProi IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    SMARTi SM00355. ZnF_C2H2. 3 hits.
    [Graphical view ]
    PROSITEi PS00028. ZINC_FINGER_C2H2_1. 3 hits.
    PS50157. ZINC_FINGER_C2H2_2. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation."
      Blok L.J., Grossmann M.E., Perry J.E., Tindall D.J.
      Mol. Endocrinol. 9:1610-1620(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), FUNCTION.
    2. "Identification of a novel TGF-beta-regulated gene encoding a putative zinc finger protein in human osteoblasts."
      Subramaniam M., Harris S.A., Oursler M.J., Rasmussen K., Riggs B.L., Spelsberg T.C.
      Nucleic Acids Res. 23:4907-4912(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    3. "TGFbeta-inducible early gene (TIEG) also codes for early growth response alpha (EGRalpha): evidence of multiple transcripts from alternate promoters."
      Fautsch M.P., Vrabel A., Subramaniam M., Hefferen T.E., Spelsberg T.C., Wieben E.D.
      Genomics 51:408-416(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    4. "Shaking the family tree: Identification of novel and biologically active alternatively spliced isoforms across the KLF family of transcription factors."
      Camacho-Vanegas O., Till J., Miranda-Lorenzo I., Ozturk B., Camacho S.C., Martignetti J.A.
      FASEB J. 27:432-436(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4), ALTERNATIVE SPLICING.
    5. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
      Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    6. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Amygdala.
    7. "DNA sequence and analysis of human chromosome 8."
      Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T.
      , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Gloeckner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C.J., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S.
      Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    9. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Tissue: Eye and Placenta.
    10. "Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue."
      Johnsen S.A., Subramaniam M., Monroe D.G., Janknecht R., Spelsberg T.C.
      J. Biol. Chem. 277:30754-30759(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH SIAH1, DEGRADATION.
    11. "Identification and characterization of a consensus DNA binding element for the zinc finger transcription factor TIEG/EGRalpha."
      Chrisman H.R., Tindall D.J.
      DNA Cell Biol. 22:187-199(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: DNA-BINDING.
    12. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-249, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    13. "Solution structure of the first and second ZF-C2H2 domains from human krueppel-like factor 10."
      RIKEN structural genomics initiative (RSGI)
      Submitted (APR-2008) to the PDB data bank
      Cited for: STRUCTURE BY NMR OF 353-423.

    Entry informationi

    Entry nameiKLF10_HUMAN
    AccessioniPrimary (citable) accession number: Q13118
    Secondary accession number(s): A8MVH0
    , B2R794, L0R4P6, L0R679, O75411, Q503B2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 143 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human chromosome 8
      Human chromosome 8: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3