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Q13023

- AKAP6_HUMAN

UniProt

Q13023 - AKAP6_HUMAN

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Protein
A-kinase anchor protein 6
Gene
AKAP6, AKAP100, KIAA0311
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes.

GO - Molecular functioni

  1. adenylate cyclase binding Source: BHF-UCL
  2. ion channel binding Source: BHF-UCL
  3. protein anchor Source: BHF-UCL
  4. protein binding Source: UniProtKB
  5. protein complex scaffold Source: BHF-UCL
  6. protein kinase A binding Source: UniProtKB
  7. protein kinase A regulatory subunit binding Source: BHF-UCL

GO - Biological processi

  1. action potential Source: BHF-UCL
  2. cAMP-mediated signaling Source: BHF-UCL
  3. cellular response to cAMP Source: BHF-UCL
  4. cellular response to cytokine stimulus Source: BHF-UCL
  5. negative regulation of cAMP biosynthetic process Source: BHF-UCL
  6. positive regulation of NFAT protein import into nucleus Source: BHF-UCL
  7. positive regulation of calcineurin-NFAT signaling cascade Source: BHF-UCL
  8. positive regulation of cell growth Source: BHF-UCL
  9. positive regulation of cell growth involved in cardiac muscle cell development Source: BHF-UCL
  10. positive regulation of delayed rectifier potassium channel activity Source: BHF-UCL
  11. positive regulation of potassium ion transmembrane transport Source: BHF-UCL
  12. positive regulation of protein phosphatase type 2B activity Source: BHF-UCL
  13. positive regulation of release of sequestered calcium ion into cytosol Source: BHF-UCL
  14. positive regulation of ryanodine-sensitive calcium-release channel activity Source: BHF-UCL
  15. protein targeting Source: UniProtKB
  16. regulation of membrane repolarization Source: BHF-UCL
  17. regulation of protein kinase A signaling Source: BHF-UCL
  18. regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Source: BHF-UCL
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
A-kinase anchor protein 6
Short name:
AKAP-6
Alternative name(s):
A-kinase anchor protein 100 kDa
Short name:
AKAP 100
Protein kinase A-anchoring protein 6
Short name:
PRKA6
mAKAP
Gene namesi
Name:AKAP6
Synonyms:AKAP100, KIAA0311
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 14

Organism-specific databases

HGNCiHGNC:376. AKAP6.

Subcellular locationi

Sarcoplasmic reticulum. Nucleus membrane
Note: In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences.

GO - Cellular componenti

  1. T-tubule Source: BHF-UCL
  2. calcium channel complex Source: BHF-UCL
  3. caveola Source: BHF-UCL
  4. cytoplasm Source: BHF-UCL
  5. intercalated disc Source: BHF-UCL
  6. junctional sarcoplasmic reticulum membrane Source: BHF-UCL
  7. nuclear envelope Source: UniProtKB
  8. nuclear membrane Source: UniProtKB-SubCell
  9. perinuclear region of cytoplasm Source: BHF-UCL
  10. sarcoplasmic reticulum Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Nucleus, Sarcoplasmic reticulum

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24670.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 23192319A-kinase anchor protein 6
PRO_0000064530Add
BLAST

Proteomic databases

PaxDbiQ13023.
PRIDEiQ13023.

PTM databases

PhosphoSiteiQ13023.

Expressioni

Tissue specificityi

Highly expressed in cardiac and skeletal muscle, followed by brain.

Gene expression databases

ArrayExpressiQ13023.
BgeeiQ13023.
CleanExiHS_AKAP6.
GenevestigatoriQ13023.

Organism-specific databases

HPAiCAB001983.

Interactioni

Subunit structurei

Interacts with RII subunit of PKA, phosphatase 2B (calcineurin) and AKAP79.

Binary interactionsi

WithEntry#Exp.IntActNotes
OPTNQ96CV92EBI-1056102,EBI-748974

Protein-protein interaction databases

BioGridi114857. 10 interactions.
IntActiQ13023. 11 interactions.
STRINGi9606.ENSP00000280979.

Structurei

3D structure databases

ProteinModelPortaliQ13023.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati762 – 84887Spectrin 1
Add
BLAST
Repeati1036 – 1150115Spectrin 2
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni2063 – 207614PKA-RII subunit binding domain
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi1560 – 1701142Ser-rich
Add
BLAST

Domaini

RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.

Sequence similaritiesi

Contains 2 spectrin repeats.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG119013.
HOGENOMiHOG000001568.
HOVERGENiHBG050480.
InParanoidiQ13023.
KOiK16523.
OMAiNGSDSLQ.
OrthoDBiEOG71G9T4.
PhylomeDBiQ13023.
TreeFamiTF105405.

Family and domain databases

InterProiIPR026696. AKAP6/CEP68.
IPR018159. Spectrin/alpha-actinin.
IPR002017. Spectrin_repeat.
[Graphical view]
PANTHERiPTHR14514. PTHR14514. 1 hit.
PfamiPF00435. Spectrin. 1 hit.
[Graphical view]
SMARTiSM00150. SPEC. 3 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q13023-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MLTMSVTLSP LRSQDLDPMA TDASPMAINM TPTVEQGEGE EAMKDMDSDQ     50
QYEKPPPLHT GADWKIVLHL PEIETWLRMT SERVRDLTYS VQQDSDSKHV 100
DVHLVQLKDI CEDISDHVEQ IHALLETEFS LKLLSYSVNV IVDIHAVQLL 150
WHQLRVSVLV LRERILQGLQ DANGNYTRQT DILQAFSEET KEGRLDSLTE 200
VDDSGQLTIK CSQNYLSLDC GITAFELSDY SPSEDLLSGL GDMTSSQVKT 250
KPFDSWSYSE MEKEFPELIR SVGLLTVAAD SISTNGSEAV TEEVSQVSLS 300
VDDKGGCEED NASAVEEQPG LTLGVSSSSG EALTNAAQPS SETVQQESSS 350
SSHHDAKNQQ PVPCENATPK RTIRDCFNYN EDSPTQPTLP KRGLFLKEET 400
FKNDLKGNGG KRQMVDLKPE MSRSTPSLVD PPDRSKLCLV LQSSYPNSPS 450
AASQSYECLH KVGNGNLENT VKFHIKEISS SLGRLNDCYK EKSRLKKPHK 500
TSEEVPPCRT PKRGTGSGKQ AKNTKSSAVP NGELSYTSKA IEGPQTNSAS 550
TSSLEPCNQR SWNAKLQLQS ETSSSPAFTQ SSESSVGSDN IMSPVPLLSK 600
HKSKKGQASS PSHVTRNGEV VEAWYGSDEY LALPSHLKQT EVLALKLENL 650
TKLLPQKPRG ETIQNIDDWE LSEMNSDSEI YPTYHVKKKH TRLGRVSPSS 700
SSDIASSLGE SIESGPLSDI LSDEESSMPL AGMKKYADEK SERASSSEKN 750
ESHSATKSAL IQKLMQDIQH QDNYEAIWEK IEGFVNKLDE FIQWLNEAME 800
TTENWTPPKA EMDDLKLYLE THLSFKLNVD SHCALKEAVE EEGHQLLELI 850
ASHKAGLKDM LRMIASQWKE LQRQIKRQHS WILRALDTIK AEILATDVSV 900
EDEEGTGSPK AEVQLCYLEA QRDAVEQMSL KLYSEQYTSS SKRKEEFADM 950
SKVHSVGSNG LLDFDSEYQE LWDWLIDMES LVMDSHDLMM SEEQQQHLYK 1000
RYSVEMSIRH LKKTELLSKV EALKKGGVLL PNDLLEKVDS INEKWELLGK 1050
TLGEKIQDTM AGHSGSSPRD LLSPESGSLV RQLEVRIKEL KGWLRDTELF 1100
IFNSCLRQEK EGTMNTEKQL QYFKSLCREI KQRRRGVASI LRLCQHLLDD 1150
RETCNLNADH QPMQLIIVNL ERRWEAIVMQ AVQWQTRLQK KMGKESETLN 1200
VIDPGLMDLN GMSEDALEWD EMDISNKLIS LNEESNDLDQ ELQPVIPSLK 1250
LGETSNEDPG YDEEADNHGG SQYASNITAP SSPHIYQVYS LHNVELYEDN 1300
HMPFLKNNPK VTGMTQPNVL TKSLSKDSSF SSTKSLPDLL GGSNLVKPCA 1350
CHGGDMSQNS GSESGIVSEG DTETTTNSEM CLLNAVDGSP SNLETEHLDP 1400
QMGDAVNVLK QKFTDEGESI KLPNSSQSSI SPVGCVNGKV GDLNSITKHT 1450
PDCLGEELQG KHDVFTFYDY SYLQGSKLKL PMIMKQSQSE KAHVEDPLLR 1500
GFYFDKKSCK SKHQTTELQP DVPPHERILA SASHEMDRIS YKSGNIEKTF 1550
TGMQNAKQLS LLSHSSSIES LSPGGDLFGL GIFKNGSDSL QRSTSLESWL 1600
TSYKSNEDLF SCHSSGDISV SSGSVGELSK RTLDLLNRLE NIQSPSEQKI 1650
KRSVSDITLQ SSSQKMSFTG QMSLDIASSI NEDSAASLTE LSSSDELSLC 1700
SEDIVLHKNK IPESNASFRK RLTRSVADES DVNVSMIVNV SCTSACTDDE 1750
DDSDLLSSST LTLTEEELCI KDEDDDSSIA TDDEIYEDCT LMSGLDYIKN 1800
ELQTWIRPKL SLTRDKKRCN VSDEMKGSKD ISSSEMTNPS DTLNIETLLN 1850
GSVKRVSENN GNGKNSSHTH ELGTKRENKK TIFKVNKDPY VADMENGNIE 1900
GIPERQKGKP NVTSKVSENL GSHGKEISES EHCKCKALMD SLDDSNTAGK 1950
EFVSQDVRHL PKKCPNHHHF ENQSTASTPT EKSFSELALE TRFNNRQDSD 2000
ALKSSDDAPS MAGKSAGCCL ALEQNGTEEN ASISNISCCN CEPDVFHQKD 2050
AEDCSVHNFV KEIIDMASTA LKSKSQPENE VAAPTSLTQI KEKVLEHSHR 2100
PIQLRKGDFY SYLSLSSHDS DCGEVTNYIE EKSSTPLPLD TTDSGLDDKE 2150
DIECFFEACV EGDSDGEEPC FSSAPPNESA VPSEAAMPLQ ATACSSEFSD 2200
SSLSADDADT VALSSPSSQE RAEVGKEVNG LPQTSSGCAE NLEFTPSKLD 2250
SEKESSGKPG ESGMPEEHNA ASAKSKVQDL SLKANQPTDK AALHPSPKTL 2300
TCEENLLNLH EKRHRNMHR 2319
Length:2,319
Mass (Da):256,720
Last modified:October 17, 2006 - v3
Checksum:i7607B71AD2140727
GO
Isoform 2 (identifier: Q13023-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1050-1075: KTLGEKIQDTMAGHSGSSPRDLLSPE → VFAFLLLFVGYVYIFCVVKYSVRFLI
     1076-2319: Missing.

Note: No experimental confirmation available.

Show »
Length:1,075
Mass (Da):120,243
Checksum:i813200266D867C38
GO

Sequence cautioni

The sequence BAA20770.2 differs from that shown. Reason: Erroneous initiation.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti337 – 3371A → V.
Corresponds to variant rs3742926 [ dbSNP | Ensembl ].
VAR_028171
Natural varianti408 – 4081N → S.
Corresponds to variant rs17099240 [ dbSNP | Ensembl ].
VAR_028172
Natural varianti558 – 5581N → D.
Corresponds to variant rs35210906 [ dbSNP | Ensembl ].
VAR_050653
Natural varianti892 – 8921E → K.
Corresponds to variant rs34572259 [ dbSNP | Ensembl ].
VAR_050654
Natural varianti910 – 9101K → M in a breast cancer sample; somatic mutation. 1 Publication
VAR_035781
Natural varianti1192 – 11921M → I in a breast cancer sample; somatic mutation. 1 Publication
VAR_035782
Natural varianti1492 – 14921A → V.1 Publication
Corresponds to variant rs11845640 [ dbSNP | Ensembl ].
VAR_028173
Natural varianti1516 – 15161T → A.
Corresponds to variant rs17099587 [ dbSNP | Ensembl ].
VAR_050655
Natural varianti1522 – 15221V → I.
Corresponds to variant rs34711402 [ dbSNP | Ensembl ].
VAR_050656
Natural varianti1702 – 17021E → Q in a breast cancer sample; somatic mutation. 1 Publication
VAR_035783
Natural varianti1839 – 18391P → T in a colorectal cancer sample; somatic mutation. 1 Publication
VAR_035784
Natural varianti2035 – 20351N → D.
Corresponds to variant rs1051695 [ dbSNP | Ensembl ].
VAR_028174
Natural varianti2171 – 21711F → Y.
Corresponds to variant rs4647899 [ dbSNP | Ensembl ].
VAR_028175
Natural varianti2209 – 22091D → H.
Corresponds to variant rs4402458 [ dbSNP | Ensembl ].
VAR_028176
Natural varianti2267 – 22671E → D.
Corresponds to variant rs35977369 [ dbSNP | Ensembl ].
VAR_050657

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1050 – 107526KTLGE…LLSPE → VFAFLLLFVGYVYIFCVVKY SVRFLI in isoform 2.
VSP_054497Add
BLAST
Alternative sequencei1076 – 23191244Missing in isoform 2.
VSP_054498Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti974 – 9741W → C in AAA92354. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U17195 mRNA. Translation: AAA92354.2.
AB002309 mRNA. Translation: BAA20770.2. Different initiation.
AL049781 Genomic DNA. No translation available.
AL117672 Genomic DNA. No translation available.
AL132988 Genomic DNA. No translation available.
AL136298 Genomic DNA. No translation available.
CH471078 Genomic DNA. Translation: EAW65931.1.
BC150185 mRNA. Translation: AAI50186.1.
BC150288 mRNA. Translation: AAI50289.1.
BC154413 mRNA. Translation: AAI54414.1.
CCDSiCCDS9644.1. [Q13023-1]
RefSeqiNP_004265.3. NM_004274.4. [Q13023-1]
UniGeneiHs.509083.

Genome annotation databases

EnsembliENST00000280979; ENSP00000280979; ENSG00000151320.
ENST00000557354; ENSP00000450531; ENSG00000151320.
GeneIDi9472.
KEGGihsa:9472.
UCSCiuc001wrq.3. human. [Q13023-1]

Polymorphism databases

DMDMi116241243.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U17195 mRNA. Translation: AAA92354.2 .
AB002309 mRNA. Translation: BAA20770.2 . Different initiation.
AL049781 Genomic DNA. No translation available.
AL117672 Genomic DNA. No translation available.
AL132988 Genomic DNA. No translation available.
AL136298 Genomic DNA. No translation available.
CH471078 Genomic DNA. Translation: EAW65931.1 .
BC150185 mRNA. Translation: AAI50186.1 .
BC150288 mRNA. Translation: AAI50289.1 .
BC154413 mRNA. Translation: AAI54414.1 .
CCDSi CCDS9644.1. [Q13023-1 ]
RefSeqi NP_004265.3. NM_004274.4. [Q13023-1 ]
UniGenei Hs.509083.

3D structure databases

ProteinModelPortali Q13023.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 114857. 10 interactions.
IntActi Q13023. 11 interactions.
STRINGi 9606.ENSP00000280979.

PTM databases

PhosphoSitei Q13023.

Polymorphism databases

DMDMi 116241243.

Proteomic databases

PaxDbi Q13023.
PRIDEi Q13023.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000280979 ; ENSP00000280979 ; ENSG00000151320 .
ENST00000557354 ; ENSP00000450531 ; ENSG00000151320 .
GeneIDi 9472.
KEGGi hsa:9472.
UCSCi uc001wrq.3. human. [Q13023-1 ]

Organism-specific databases

CTDi 9472.
GeneCardsi GC14P032798.
HGNCi HGNC:376. AKAP6.
HPAi CAB001983.
MIMi 604691. gene.
neXtProti NX_Q13023.
PharmGKBi PA24670.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG119013.
HOGENOMi HOG000001568.
HOVERGENi HBG050480.
InParanoidi Q13023.
KOi K16523.
OMAi NGSDSLQ.
OrthoDBi EOG71G9T4.
PhylomeDBi Q13023.
TreeFami TF105405.

Miscellaneous databases

GeneWikii AKAP6.
GenomeRNAii 9472.
NextBioi 35463252.
PROi Q13023.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q13023.
Bgeei Q13023.
CleanExi HS_AKAP6.
Genevestigatori Q13023.

Family and domain databases

InterProi IPR026696. AKAP6/CEP68.
IPR018159. Spectrin/alpha-actinin.
IPR002017. Spectrin_repeat.
[Graphical view ]
PANTHERi PTHR14514. PTHR14514. 1 hit.
Pfami PF00435. Spectrin. 1 hit.
[Graphical view ]
SMARTi SM00150. SPEC. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes."
    Kapiloff M.S., Shillace R.V., Westphal A.M., Scott J.D.
    J. Cell Sci. 112:2725-2736(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT VAL-1492.
  2. "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
    Nagase T., Ishikawa K., Nakajima D., Ohira M., Seki N., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 4:141-150(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
    Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
    DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION.
  4. "The DNA sequence and analysis of human chromosome 14."
    Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
    , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
    Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
  7. "Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum."
    McCartney S., Little B.M., Langeberg L.K., Scott J.D.
    J. Biol. Chem. 270:9327-9333(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1666-2319 (ISOFORM 1).
    Tissue: Hippocampus.
  8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. Cited for: VARIANTS [LARGE SCALE ANALYSIS] MET-910; ILE-1192; GLN-1702 AND THR-1839.

Entry informationi

Entry nameiAKAP6_HUMAN
AccessioniPrimary (citable) accession number: Q13023
Secondary accession number(s): A7E242, A7E2D4, O15028
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: October 17, 2006
Last modified: September 3, 2014
This is version 124 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi