Reviewed, UniProtKB/Swiss-Prot Q12ZU3 (RNP1_METBU)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 1
      Short name=RNase P component 1
    EC=3.1.26.5

Gene names

Name:	rnp1
Ordered Locus Names:	Mbur_0009

Organism

Methanococcoides burtonii (strain DSM 6242) [Complete proteome] [HAMAP]

Taxonomic identifier

259564 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanococcoides

Protein attributes

Sequence length	101 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00754
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00754
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential. HAMAP MF_00754
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Cellular component	ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro ribonuclease P complex Inferred from electronic annotation. Source: InterPro
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 101	101	Ribonuclease P protein component 1 HAMAP MF_00754		PRO_1000046614

Sequences

	Sequence		Length	Mass (Da)
	Q12ZU3-1 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: E274A5993BD66FA2	FASTA	101	11,649
	10 20 30 40 50 60 MEALPSNLIF HELIGLYAEV FESTNPKLIN ICGRVIDETR NMLIIETEDT HEKMVPKNGT 70 80 90 100 TFVFHLPSSS ADHDQRVKIF GTLLLSQPEN RVKNIRKIRM R

References

[1]

"Complete sequence of Methanococcoides burtonii DSM 6242." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Kadner K., Aerts A., Dehal P., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Anderson I., Franzmann P., Thomas T., Saunders N., Cavicchioli R., Sowers K., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000300 Genomic DNA. Translation: ABE51033.1.
RefSeq	YP_564783.1.
3D structure databases
SMR	Q12ZU3. Positions 4-94.
ModBase	Search...
Protein-protein interaction databases
STRING	Q12ZU3.
Genome annotation databases
GeneID	3996909.
GenomeReviews	Gene locus Mbur_0009 in contig CP000300_GR.
KEGG	mbu:Mbur_0009.
NMPDR	fig|259564.8.peg.9.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG12604.
HOGENOM	HBG704950.
OMA	VINETRN.
Enzyme and pathway databases
BioCyc	MBUR259564:MBUR_0009-MONOMER.
Family and domain databases
HAMAP	MF_00754. RNase_P_1. [Tree]
InterPro	IPR002730. RNase_P/MRP_p29_euk/arc. [Graphical view]
Gene3D	G3DSA:2.30.30.210. RNase_P_Rpp29. 1 hit.
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNP1_METBU

Accession

Primary (citable) accession number: Q12ZU3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 22, 2006
Last modified:	January 19, 2010
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)