Reviewed, UniProtKB/Swiss-Prot Q12ZC2 (RNP3_METBU)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 3
      Short name=RNase P component 3
    EC=3.1.26.5

Gene names

Name:	rnp3
Ordered Locus Names:	Mbur_0194

Organism

Methanococcoides burtonii (strain DSM 6242) [Complete proteome] [HAMAP]

Taxonomic identifier

259564 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanococcoides

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00756
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00756
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential. HAMAP MF_00756
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 241	241	Ribonuclease P protein component 3 HAMAP MF_00756		PRO_1000046626

Sequences

	Sequence		Length	Mass (Da)
	Q12ZC2-1 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: 2684C2338107F084	FASTA	241	26,256
	10 20 30 40 50 60 MAERSFYDLS IHYVPDGKNT AEELISMAKH LGFAGIGLSN HSTAEGPLKS DGTEGFDIFR 70 80 90 100 110 120 TVELVASNPS KLHGLVGKYR NKVDVLAVHG GDEGINRAAV ENSNVDILIH PFTPKGSGLN 130 140 150 160 170 180 HVLAKSASEN NVAIAFDIDS LIMSRGGRRV HSLSHFRDYL ALSRKYDVPM LLTSNALSIF 190 200 210 220 230 240 GLRAPREIIA LAALFGMEKD EAIMALSETP LKIVQKKRHD KNYVCEGVEI FEPSPSVLGD E

References

[1]

"Complete sequence of Methanococcoides burtonii DSM 6242." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Kadner K., Aerts A., Dehal P., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Anderson I., Franzmann P., Thomas T., Saunders N., Cavicchioli R., Sowers K., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000300 Genomic DNA. Translation: ABE51204.1.
RefSeq	YP_564954.1.
3D structure databases
SMR	Q12ZC2. Positions 21-215.
ModBase	Search...
Protein-protein interaction databases
STRING	Q12ZC2.
Genome annotation databases
GeneID	3997161.
GenomeReviews	Gene locus Mbur_0194 in contig CP000300_GR.
KEGG	mbu:Mbur_0194.
NMPDR	fig|259564.8.peg.183.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG09152.
HOGENOM	HBG551632.
OMA	ENPRVDI.
Enzyme and pathway databases
BioCyc	MBUR259564:MBUR_0194-MONOMER.
Family and domain databases
HAMAP	MF_00756. RNase_P_3. [Tree]
InterPro	IPR016195. Pol/histidinol_Pase-like. IPR002738. RNase_P_p30. [Graphical view]
PANTHER	PTHR13031. RNase_P_p30. 1 hit.
Pfam	PF01876. RNase_P_p30. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNP3_METBU

Accession

Primary (citable) accession number: Q12ZC2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	August 22, 2006
Last modified:	January 19, 2010
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)