ID   MCH_METBU               Reviewed;         320 AA.
AC   Q12Y52;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   16-JUN-2009, entry version 20.
DE   RecName: Full=Methenyltetrahydromethanopterin cyclohydrolase;
DE            EC=3.5.4.27;
DE   AltName: Full=Methenyl-H4MPT cyclohydrolase;
GN   Name=mch; OrderedLocusNames=Mbur_0653;
OS   Methanococcoides burtonii (strain DSM 6242).
OC   Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales;
OC   Methanosarcinaceae; Methanococcoides.
OX   NCBI_TaxID=259564;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Kadner K., Aerts A., Dehal P., Pitluck S., Martinez M., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Anderson I.,
RA   Franzmann P., Thomas T., Saunders N., Cavicchioli R., Sowers K.,
RA   Richardson P.;
RT   "Complete sequence of Methanococcoides burtonii DSM 6242.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-
CC       formyl-H(4)MPT (By similarity).
CC   -!- CATALYTIC ACTIVITY: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin
CC       + H(2)O = 5-formyl-5,6,7,8-tetrahydromethanopterin.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the MCH family.
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DR   EMBL; CP000300; ABE51624.1; -; Genomic_DNA.
DR   RefSeq; YP_565374.1; -.
DR   GeneID; 3997983; -.
DR   GenomeReviews; CP000300_GR; Mbur_0653.
DR   KEGG; mbu:Mbur_0653; -.
DR   NMPDR; fig|259564.8.peg.612; -.
DR   HOGENOM; Q12Y52; -.
DR   OMA; Q12Y52; YFAMGSG.
DR   BioCyc; MBUR259564:MBUR_0653-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0018759; F:methenyltetrahydromethanopterin cyclohydrol...; IEA:HAMAP.
DR   GO; GO:0006730; P:one-carbon compound metabolic process; IEA:HAMAP.
DR   HAMAP; MF_00486; -; 1.
DR   InterPro; IPR003209; METHMP_CycHdrlase.
DR   Pfam; PF02289; MCH; 1.
DR   ProDom; PD011637; Cyclohydrolase; 1.
DR   TIGRFAMs; TIGR03120; one_C_mch; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Hydrolase; One-carbon metabolism.
FT   CHAIN         1    320       Methenyltetrahydromethanopterin
FT                                cyclohydrolase.
FT                                /FTId=PRO_1000014397.
SQ   SEQUENCE   320 AA;  34558 MW;  87BC237981F3FA3E CRC64;
     MISVNEKGLA IIDEMLDWEE DVKIESKVLE NGATIIDCGV NVEGGYDAGM YLSRLCLADL
     AEISYTKVDL EGLAVPAIQI ATDHPTIACM ASQYAGWRIA VGDYFGMGSG PARGLGLKPK
     ELYEEIGYKD EADAAVLVME SDKLPTEEIV EYIAKHCSVE PQNVFIAVAP TSSIAGSVQI
     SARVVETGIH KLESIGYDIN KIKSGFGVAP IAPIVGDDTK CMGSTNDCII YCGETYYTVE
     DGNAEELEDF VKKAPSSTSR DFGKPFYTTF KEAGFDFFKV DAGMFAPAKI TINDLKSKKS
     FTSGRINPGI LLESFGIKNV
//