Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q12X18

- AROA_METBU

UniProt

Q12X18 - AROA_METBU

Protein

Probable 3-phosphoshikimate 1-carboxyvinyltransferase

Gene

aroA

Organism
Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (22 Aug 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. 3-phosphoshikimate 1-carboxyvinyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aromatic amino acid family biosynthetic process Source: UniProtKB-KW
    2. chorismate biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis

    Enzyme and pathway databases

    BioCyciMBUR259564:GHBZ-1099-MONOMER.
    UniPathwayiUPA00053; UER00089.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable 3-phosphoshikimate 1-carboxyvinyltransferaseUniRule annotation (EC:2.5.1.19UniRule annotation)
    Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate synthaseUniRule annotation
    Short name:
    EPSP synthaseUniRule annotation
    Short name:
    EPSPSUniRule annotation
    Gene namesi
    Name:aroAUniRule annotation
    Ordered Locus Names:Mbur_1078
    OrganismiMethanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)
    Taxonomic identifieri259564 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanococcoides
    ProteomesiUP000001979: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 427427Probable 3-phosphoshikimate 1-carboxyvinyltransferasePRO_1000012450Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi259564.Mbur_1078.

    Structurei

    3D structure databases

    ProteinModelPortaliQ12X18.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the EPSP synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0128.
    HOGENOMiHOG000247372.
    KOiK00800.
    OMAiSYDDHRM.

    Family and domain databases

    Gene3Di3.65.10.10. 2 hits.
    HAMAPiMF_00210. EPSP_synth.
    InterProiIPR001986. Enolpyruvate_Tfrase_dom.
    IPR006264. EPSP_synthase.
    IPR023193. EPSP_synthase_CS.
    IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
    [Graphical view]
    PfamiPF00275. EPSP_synthase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000505. EPSPS. 1 hit.
    SUPFAMiSSF55205. SSF55205. 1 hit.
    TIGRFAMsiTIGR01356. aroA. 1 hit.
    PROSITEiPS00104. EPSP_SYNTHASE_1. 1 hit.
    PS00885. EPSP_SYNTHASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q12X18-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKVTVGRSGV HGEIFAPASK SYTHRAITVA ALSKESIIHR PLISADTQST    50
    IKACEMLGAY IEKDGDKLLI SGVDGEPQTP DNVIDVGNSG TTLRFMTAIA 100
    ALGQGTTVLT GDNSIRSRPN GPLLQVLNDL GVQSISTRGD GCAPIVVTGG 150
    LKGAIAKIDG SISSQFISAL LLACPLTKNS TTLSIKGELK SRPYVDVTLD 200
    ILEKAGAEIY LEDNQNLKFI IPGNQKYRLK EYTVPGDFSS ASYLLAAAAM 250
    TDTKIKVNNL YPSMQGDAAI IDILKEMGAN IYWNKEEGTV EVNGGKLHGI 300
    TMDAGATPDL VPTVAVLGAV AEGETVITNA EHVRYKETDR LHAMAVELDK 350
    MGISTSEEKD KLTIKGGELK GADVHGWHDH RIVMSLTLAG MIAGDTTIDT 400
    AEAIFISYPN FFDSMRSIGA DVILSEQ 427
    Length:427
    Mass (Da):45,424
    Last modified:August 22, 2006 - v1
    Checksum:iD27049A1FF358E31
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000300 Genomic DNA. Translation: ABE52008.1.
    RefSeqiYP_565758.1. NC_007955.1.

    Genome annotation databases

    EnsemblBacteriaiABE52008; ABE52008; Mbur_1078.
    GeneIDi3998015.
    KEGGimbu:Mbur_1078.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000300 Genomic DNA. Translation: ABE52008.1 .
    RefSeqi YP_565758.1. NC_007955.1.

    3D structure databases

    ProteinModelPortali Q12X18.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 259564.Mbur_1078.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE52008 ; ABE52008 ; Mbur_1078 .
    GeneIDi 3998015.
    KEGGi mbu:Mbur_1078.

    Phylogenomic databases

    eggNOGi COG0128.
    HOGENOMi HOG000247372.
    KOi K00800.
    OMAi SYDDHRM.

    Enzyme and pathway databases

    UniPathwayi UPA00053 ; UER00089 .
    BioCyci MBUR259564:GHBZ-1099-MONOMER.

    Family and domain databases

    Gene3Di 3.65.10.10. 2 hits.
    HAMAPi MF_00210. EPSP_synth.
    InterProi IPR001986. Enolpyruvate_Tfrase_dom.
    IPR006264. EPSP_synthase.
    IPR023193. EPSP_synthase_CS.
    IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
    [Graphical view ]
    Pfami PF00275. EPSP_synthase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000505. EPSPS. 1 hit.
    SUPFAMi SSF55205. SSF55205. 1 hit.
    TIGRFAMsi TIGR01356. aroA. 1 hit.
    PROSITEi PS00104. EPSP_SYNTHASE_1. 1 hit.
    PS00885. EPSP_SYNTHASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 6242 / NBRC 107633 / OCM 468 / ACE-M.

    Entry informationi

    Entry nameiAROA_METBU
    AccessioniPrimary (citable) accession number: Q12X18
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: August 22, 2006
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3