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Q12WB6 (Q12WB6_METBU) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-acetyl-gamma-glutamyl-phosphate reductase HAMAP MF_00150
Short name=AGPR HAMAP MF_00150
EC=1.2.1.38 HAMAP MF_00150
Alternative name(s):
N-acetyl-glutamate semialdehyde dehydrogenase HAMAP MF_00150
Gene names
Name:argC HAMAP MF_00150
Ordered Locus Names:Mbur_1342
OrganismMethanococcoides burtonii (strain DSM 6242) [Complete proteome] [HAMAP]
Taxonomic identifier259564 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanococcoides

Protein attributes

Sequence length340 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH. HAMAP MF_00150

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate. RuleBase RU004258

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4. HAMAP MF_00150

Subcellular location

Cytoplasm By similarity HAMAP MF_00150.

Sequence similarities

Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. HAMAP MF_00150

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1481 By similarity HAMAP MF_00150

Sequences

Sequence LengthMass (Da)Tools
Q12WB6 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 89AEED5E88C4BE13

FASTA34037,234
        10         20         30         40         50         60 
MTDMINAGIV GASGYTGGEL MRLLLNHPYV NIETATSRRL SGEAVSDTHK HLRGLVDIEF 

        70         80         90        100        110        120 
EDLSPEDIRG RCDVVFVAVP HGTAMNIVPE LIDDNTKVID LSADYRLKTS VFEQVYNMEH 

       130        140        150        160        170        180 
VDPRDAVFGL VELHPEVKDE SFVANPGCYP TGAILSAAPL TAAKLLKMAI FDSKSGITGA 

       190        200        210        220        230        240 
GINPTMVSHY PNMAENVQAY KLTTHRHREE ILQELNRLDN AFTDVNFTPH VVPSIRGILT 

       250        260        270        280        290        300 
TAHLFTKEKM SLEDVRGLYH EFYKNKPFVR VVDDIPSLSA VKGSNFCDIG FEVDANTGRV 

       310        320        330        340 
VVVSAIDNLV KGASGQAIQN MNLMCGFDET TGLRIAATSP

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References

[1]"Complete sequence of Methanococcoides burtonii DSM 6242."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Kadner K., Aerts A., Dehal P., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Anderson I., Franzmann P., Thomas T., Saunders N., Cavicchioli R., Sowers K., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 6242.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000300 Genomic DNA. Translation: ABE52260.1.
RefSeqYP_566010.1. NC_007955.1.

3D structure databases

ProteinModelPortalQ12WB6.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ12WB6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3997558.
GenomeReviewsGene locus Mbur_1342 in contig CP000300_GR.
KEGGmbu:Mbur_1342.
NMPDRfig|259564.8.peg.1272.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG05044.
HOGENOMHBG294213.
OMAVCRIAVH.
PhylomeDBQ12WB6.
ProtClustDBPRK00436.

Family and domain databases

HAMAPMF_00150. ArgC_type1.
[Tree]
InterProIPR023013. AGPR_AS.
IPR000706. AGPR_type-1.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
IPR012280. Semialdhyde_DH_dimer_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00145.
PfamPF01118. Semialdhyde_dh. 1 hit.
PF02774. Semialdhyde_dhC. 1 hit.
[Graphical view]
SMARTSM00859. Semialdhyde_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR01850. ArgC. 1 hit.
PROSITEPS01224. ARGC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ12WB6_METBU
AccessionPrimary (citable) accession number: Q12WB6
Entry history
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: November 16, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info