ID   MTRE_METBU              Reviewed;         301 AA.
AC   Q12VU4;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=Tetrahydromethanopterin S-methyltransferase subunit E;
DE            EC=2.1.1.86;
DE   AltName: Full=N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E;
GN   Name=mtrE; OrderedLocusNames=Mbur_1525;
OS   Methanococcoides burtonii (strain DSM 6242).
OC   Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales;
OC   Methanosarcinaceae; Methanococcoides.
OX   NCBI_TaxID=259564;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Kadner K., Aerts A., Dehal P., Pitluck S., Martinez M., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Anderson I.,
RA   Franzmann P., Thomas T., Saunders N., Cavicchioli R., Sowers K.,
RA   Richardson P.;
RT   "Complete sequence of Methanococcoides burtonii DSM 6242.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of a complex that catalyzes the formation of
CC       methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and
CC       methyl-tetrahydromethanopterin. This is an energy-conserving,
CC       sodium-ion translocating step (By similarity).
CC   -!- CATALYTIC ACTIVITY: 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-
CC       mercaptoethanesulfonate = 5,6,7,8-tetrahydromethanopterin + 2-
CC       (methylthio)ethanesulfonate.
CC   -!- SUBUNIT: The complex is composed of 8 subunits; mtrA, mtrB, mtrC,
CC       mtrD, mtrE, mtrF, mtrG and mtrH (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC       (Potential).
CC   -!- SIMILARITY: Belongs to the mtrE family.
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DR   EMBL; CP000300; ABE52432.1; -; Genomic_DNA.
DR   RefSeq; YP_566182.1; -.
DR   GeneID; 3997348; -.
DR   GenomeReviews; CP000300_GR; Mbur_1525.
DR   KEGG; mbu:Mbur_1525; -.
DR   NMPDR; fig|259564.8.peg.1452; -.
DR   HOGENOM; Q12VU4; -.
DR   OMA; Q12VU4; SNPNSQV.
DR   BioCyc; MBUR259564:MBUR_1525-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0012506; C:vesicle membrane; IEA:InterPro.
DR   GO; GO:0030269; F:tetrahydromethanopterin S-methyltransferase...; IEA:HAMAP.
DR   GO; GO:0006730; P:one-carbon compound metabolic process; IEA:HAMAP.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   HAMAP; MF_01098; -; 1.
DR   InterPro; IPR005780; MeTrfase_E.
DR   Pfam; PF04206; MtrE; 1.
DR   PIRSF; PIRSF016509; MtrE; 1.
DR   TIGRFAMs; TIGR01113; mtrE; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Complete proteome; Membrane; Methyltransferase;
KW   One-carbon metabolism; Transferase; Transmembrane.
FT   CHAIN         1    301       Tetrahydromethanopterin S-
FT                                methyltransferase subunit E.
FT                                /FTId=PRO_1000064943.
FT   TRANSMEM     85    105       Potential.
FT   TRANSMEM    130    150       Potential.
FT   TRANSMEM    151    171       Potential.
FT   TRANSMEM    232    252       Potential.
FT   TRANSMEM    258    278       Potential.
SQ   SEQUENCE   301 AA;  31934 MW;  E88BD4537D22C5C5 CRC64;
     MEPLMGMGVL ALMGAAATIA GTTEDLESDV GSQSNPNSQV QLAPQMMYPH RIYNKAISGE
     PPSNALICAI GGTVASVLMT ANLSVIFAIA IGALVASAVH GTYCITAYMG RTASQKRFRQ
     PIYLDILRSH TPVMMGYAFI TTFCILVVSY IMVAVLAHPF PLTLLAFIWG ITVGAIGSST
     GDVHYGAERE FQNVEFGSGL NAANSGNIVR KAESGLRNGI DNSWFCAKFG GPVTGLAFGM
     TVFLSGWVTA VFNPAISLTM GWLSVAAGVI LVLLLIIWNR KIEVAARKAF GPYKEEEEVA
     A
//