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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMBUR259564:G1G6A-1813-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Mbur_1739
OrganismiMethanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)
Taxonomic identifieri259564 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanococcoides
Proteomesi
  • UP000001979 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000180601 – 567Arginine--tRNA ligaseAdd BLAST567

Interactioni

Protein-protein interaction databases

STRINGi259564.Mbur_1739

Structurei

3D structure databases

ProteinModelPortaliQ12V97
SMRiQ12V97
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi121 – 131"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00487 Archaea
COG0018 LUCA
HOGENOMiHOG000247213
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG093Z013U

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q12V97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLDFIDQVT SILNDAVSSA GFEADDMELG PSQHADLSSR IAFRLASVAK
60 70 80 90 100
QSPKDVAEKI AGEIVIPKGS FVEKVEALGP YLNIWAGRNF IEGTVLAIRE
110 120 130 140 150
QKEAFGGNFS EGRILLEHTS ANPNGPLHVG HIRNSIIGDT LGRILKRAGY
160 170 180 190 200
DVELHYYVND MGRQIAIVSW ALGYFEFDES SKPDHAIADV YIKANAELNA
210 220 230 240 250
HPEKVAEIDK LMQLVEKGDA ATIETFDKAV DLAVSGIKET LKKMNVAHDE
260 270 280 290 300
FPKESSFIRS GDVSRIIEEI KATGRTEIDN GALVVNLQDY GFKKTLVIQR
310 320 330 340 350
TDGTSLYTTR DLAYHEWKGE RADRIIDVFG ADHKLISGQL KATLNAIGKK
360 370 380 390 400
EPEFVIFEFV SLPEGSMSTR SGKFISADDL LDQIKTQAYE EVDKRRPDMP
410 420 430 440 450
DDFKATVAEI VGIGAVRYDI VKVSPEKSTV FDWKEALDFE KQGGPFIQYS
460 470 480 490 500
HARACSILQK AKDEGLWSSE EPINTTLLVE DSEVSLIKKM AMFDNMLDQC
510 520 530 540 550
AKELRPHTFA IYARELADAF NQFYRFVSVL NAEDEQLRSS RIALVDCARM
560
VLANTLDTLG LGAPESM
Length:567
Mass (Da):62,992
Last modified:August 22, 2006 - v1
Checksum:i96D776C3D8F2CD6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000300 Genomic DNA Translation: ABE52629.1
RefSeqiWP_011499772.1, NC_007955.1

Genome annotation databases

EnsemblBacteriaiABE52629; ABE52629; Mbur_1739
GeneIDi3997299
KEGGimbu:Mbur_1739

Similar proteinsi

Entry informationi

Entry nameiSYR_METBU
AccessioniPrimary (citable) accession number: Q12V97
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 22, 2006
Last modified: February 28, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome