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Q12UL5 (APGM_METBU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1
Gene names
Name:apgM
Ordered Locus Names:Mbur_1982
OrganismMethanococcoides burtonii (strain DSM 6242) [Complete proteome] [HAMAP]
Taxonomic identifier259564 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanococcoides

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_A

Catalytic activity

2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_A

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_A

Sequence similarities

Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
   Biological processGlycolysis
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: InterPro

phosphoglycerate mutase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4014012,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_A
PRO_1000068381

Sequences

Sequence LengthMass (Da)Tools
Q12UL5 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: D131D7F35BE291C4

FASTA40143,174
        10         20         30         40         50         60 
MKYIILIGDG MADHPLEELG GMTALQKANT PNMDQMTKNG LAGLAINVPE GYSPGSDVAN 

        70         80         90        100        110        120 
MSVMGYDPAL YYSGRAPLEA ASMGIPLEVN DVAFRCNLIT IRDGLITDHS AGHITSEEAR 

       130        140        150        160        170        180 
ELIEAVDAEL GSEGLKFYPG ISYRHLLVAS NGLGANADCT PPHDVIDGEI NDHMPRGDGS 

       190        200        210        220        230        240 
DVLGKLIEGS IPILEGHPIN EKRISEGKNP GNSVWFWGQG YAPSFRTFED LYGLTGSVIS 

       250        260        270        280        290        300 
AVDLIMGLGI YAGLDVIEVP GATGYLDTNY VGKAEFAMAS LKDKDFVVVH VEAPDEAGHM 

       310        320        330        340        350        360 
GDIEAKLQAI EDFDEKVVGT VLRAARESDE DYTIVVLPDH PTPIALRTHT SEPVPFVMYS 

       370        380        390        400 
TLEDEVDDVE TFDEDAMKKG SLGIVRGCDL VQLMMERAKQ A

« Hide

References

[1]"Complete sequence of Methanococcoides burtonii DSM 6242."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Kadner K., Aerts A., Dehal P., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Anderson I., Franzmann P., Thomas T., Saunders N., Cavicchioli R., Sowers K., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 6242.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000300 Genomic DNA. Translation: ABE52861.1.
RefSeqYP_566611.1. NC_007955.1.

3D structure databases

ProteinModelPortalQ12UL5.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ12UL5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3996934.
GenomeReviewsGene locus Mbur_1982 in contig CP000300_GR.
KEGGmbu:Mbur_1982.
NMPDRfig|259564.8.peg.1894.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG04733.
HOGENOMHBG463247.
OMAANSIWLW.
ProtClustDBPRK04200.

Enzyme and pathway databases

BioCycMBUR259564:MBUR_1982-MONOMER.

Family and domain databases

HAMAPMF_01402_A. ApgM_A.
[Tree]
InterProIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR023665. ApgAM.
IPR004456. BisP-indep_Pglycerate_Mutase.
IPR013371. Homoserine_kinase_put.
IPR006124. Metalloenzyme.
[Graphical view]
Gene3DG3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KOK15635.
PfamPF01676. Metalloenzyme. 1 hit.
PF10143. PhosphMutase. 1 hit.
[Graphical view]
PIRSFPIRSF006392. IPGAM_arch. 1 hit.
SUPFAMSSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMsTIGR00306. ApgM. 1 hit.
TIGR02535. Hyp_Hser_kinase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAPGM_METBU
AccessionPrimary (citable) accession number: Q12UL5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 22, 2006
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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