Reviewed, UniProtKB/Swiss-Prot Q12UL5 (APGM_METBU)

Names and origin

Protein names

Recommended name:
    2,3-bisphosphoglycerate-independent phosphoglycerate mutase
      Short name=Phosphoglyceromutase
      Short name=BPG-independent PGAM
      Short name=aPGAM
    EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	Mbur_1982

Organism

Methanococcoides burtonii (strain DSM 6242) [Complete proteome] [HAMAP]

Taxonomic identifier

259564 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanococcoides

Protein attributes

Sequence length	401 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity.
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 401	401	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402		PRO_1000068381

Sequences

	Sequence		Length	Mass (Da)
	Q12UL5-1 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: D131D7F35BE291C4	FASTA	401	43,174
	10 20 30 40 50 60 MKYIILIGDG MADHPLEELG GMTALQKANT PNMDQMTKNG LAGLAINVPE GYSPGSDVAN 70 80 90 100 110 120 MSVMGYDPAL YYSGRAPLEA ASMGIPLEVN DVAFRCNLIT IRDGLITDHS AGHITSEEAR 130 140 150 160 170 180 ELIEAVDAEL GSEGLKFYPG ISYRHLLVAS NGLGANADCT PPHDVIDGEI NDHMPRGDGS 190 200 210 220 230 240 DVLGKLIEGS IPILEGHPIN EKRISEGKNP GNSVWFWGQG YAPSFRTFED LYGLTGSVIS 250 260 270 280 290 300 AVDLIMGLGI YAGLDVIEVP GATGYLDTNY VGKAEFAMAS LKDKDFVVVH VEAPDEAGHM 310 320 330 340 350 360 GDIEAKLQAI EDFDEKVVGT VLRAARESDE DYTIVVLPDH PTPIALRTHT SEPVPFVMYS 370 380 390 400 TLEDEVDDVE TFDEDAMKKG SLGIVRGCDL VQLMMERAKQ A

References

[1]

"Complete sequence of Methanococcoides burtonii DSM 6242." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Kadner K., Aerts A., Dehal P., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Anderson I., Franzmann P., Thomas T., Saunders N., Cavicchioli R., Sowers K., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000300 Genomic DNA. Translation: ABE52861.1.
RefSeq	YP_566611.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3996934.
GenomeReviews	Gene locus Mbur_1982 in contig CP000300_GR.
KEGG	mbu:Mbur_1982.
NMPDR	fig|259564.8.peg.1894.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q12UL5.
OMA	Q12UL5. GATGYLD.
Enzyme and pathway databases
BioCyc	MBUR259564:MBUR_1982-MON.
Family and domain databases
HAMAP	MF_01402. [Tree]
InterPro	IPR004456. APGAM_arc. IPR019304. bisP-indep_Pglycerate_Mutase. IPR013371. Homoserine_kin_put. IPR006124. Metalloenzyme. [Graphical view]
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
ProDom	PD004704. APGAM_DeoB. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00306. apgM. 1 hit. TIGR02535. hyp_Hser_kinase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_METBU

Accession

Primary (citable) accession number: Q12UL5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	August 22, 2006
Last modified:	June 16, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)