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Q12UG6 (PGP_METBU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoglycolate phosphatase
Short name=PGP
Short name=PGPase
EC=3.1.3.18
Gene names
Ordered Locus Names:Mbur_2034
OrganismMethanococcoides burtonii (strain DSM 6242) [Complete proteome] [HAMAP]
Taxonomic identifier259564 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanococcoides

Protein attributes

Sequence length226 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of 2-phosphoglycolate By similarity. HAMAP MF_01419

Catalytic activity

2-phosphoglycolate + H2O = glycolate + phosphate. HAMAP MF_01419

Cofactor

Magnesium By similarity. HAMAP MF_01419

Sequence similarities

Belongs to the archaeal SPP-like hydrolase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmagnesium ion binding

Inferred from electronic annotation. Source: InterPro

phosphoglycolate phosphatase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 226226Phosphoglycolate phosphatase HAMAP MF_01419
PRO_1000024289

Sites

Active site91Nucleophile By similarity
Metal binding91Magnesium By similarity
Metal binding111Magnesium By similarity
Metal binding1731Magnesium By similarity
Metal binding1771Magnesium By similarity
Binding site1501Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q12UG6 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: C2B2DD05D6645E8C

FASTA22624,084
        10         20         30         40         50         60 
MVLKAIVIDI DGTITNPDRS LDLDVAKRFR ELNVPVILST GNPLCYVHAA AKLIGISGIV 

        70         80         90        100        110        120 
IAENGGVIST GFDSPSIIAD GKEECEKAYE LLSQYHDLVK LDDAYRKTEV VLNRDVAVED 

       130        140        150        160        170        180 
LRSTLSENGI DIEIIDTGYA IHIKSTAMNK GTGLLKVAEL MGLEPTDYLA IGDSCNDAEM 

       190        200        210        220 
MQVAGFGIAV ANADSDAIKA ARHITKASFG KGALEAIEYA LSNGLL

« Hide

References

[1]"Complete sequence of Methanococcoides burtonii DSM 6242."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Kadner K., Aerts A., Dehal P., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Anderson I., Franzmann P., Thomas T., Saunders N., Cavicchioli R., Sowers K., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 6242.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000300 Genomic DNA. Translation: ABE52910.1.
RefSeqYP_566660.1. NC_007955.1.

3D structure databases

ProteinModelPortalQ12UG6.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ12UG6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3997416.
GenomeReviewsGene locus Mbur_2034 in contig CP000300_GR.
KEGGmbu:Mbur_2034.
NMPDRfig|259564.8.peg.1944.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG09493.
HOGENOMHBG551920.
OMANNTIYES.
ProtClustDBPRK01158.

Enzyme and pathway databases

BioCycMBUR259564:MBUR_2034-MONOMER.

Family and domain databases

HAMAPMF_01419. GPH_hydrolase_arch.
[Tree]
InterProIPR023214. HAD-like_dom.
IPR013200. HAD-SF_hydro-like_3.
IPR006382. SPPlik_hydro_arc.
IPR006378. Suc_phosP.
[Graphical view]
Gene3DG3DSA:3.40.50.1000. HAD-like_dom. 2 hits.
KOK07024.
PfamPF08282. Hydrolase_3. 2 hits.
[Graphical view]
SUPFAMSSF56784. HAD-like_dom. 1 hit.
TIGRFAMsTIGR01487. SPP-like. 1 hit.
TIGR01482. SPP-subfamily. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGP_METBU
AccessionPrimary (citable) accession number: Q12UG6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 22, 2006
Last modified: January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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