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Q12U91 (Q12U91_METBU) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroline-5-carboxylate reductase RuleBase RU003903
EC=1.5.1.2 RuleBase RU003903
Gene names
Name:proC EMBL ABE52985.1
Ordered Locus Names:Mbur_2111
OrganismMethanococcoides burtonii (strain DSM 6242) [Complete proteome] [HAMAP]
Taxonomic identifier259564 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanococcoides

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H. RuleBase RU003903

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1. RuleBase RU003903

Sequence similarities

Belongs to the pyrroline-5-carboxylate reductase family. RuleBase RU003903

Sequences

Sequence LengthMass (Da)Tools
Q12U91 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 4ACAAAFEAC7B3BBD

FASTA26928,075
        10         20         30         40         50         60 
MHLTEKRIGF IGTGKMGESL IRGILAAHSE ITLNASDVYK PALERLNNEL GINVSTDNTE 

        70         80         90        100        110        120 
TIGDSDVVVL AVKPQILKDV LVAIKDSITA DKLVISIAAG VSVTAIEDEL NEGTRVVRVM 

       130        140        150        160        170        180 
PNIAATVAEA ASAVCAGKNA TEDDMEVALE MFQSIGSAIT IPEKLMDAVT GLSGSGPAYI 

       190        200        210        220        230        240 
FPVIEALADG AVHEGLDRAN AITLAAQTVL GAAKMVLETG MHPGELKDMV TSPAGTTIRG 

       250        260 
IHTLEESGIR AAFMNAVIES SKRSKELGK

« Hide

References

[1]"Complete sequence of Methanococcoides burtonii DSM 6242."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Kadner K., Aerts A., Dehal P., Pitluck S., Martinez M., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Anderson I., Franzmann P., Thomas T., Saunders N., Cavicchioli R., Sowers K., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 6242.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000300 Genomic DNA. Translation: ABE52985.1.
RefSeqYP_566735.1. NC_007955.1.

3D structure databases

ProteinModelPortalQ12U91.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ12U91.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3998194.
GenomeReviewsGene locus Mbur_2111 in contig CP000300_GR.
KEGGmbu:Mbur_2111.
NMPDRfig|259564.8.peg.2019.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG08187.
HOGENOMHBG726602.
OMARTFNEHQ.
PhylomeDBQ12U91.
ProtClustDBCLSK450531.

Family and domain databases

InterProIPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR004455. NADP_OxRdtase_F420.
IPR000304. Pyrroline-COOH_reductase.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00286.
PANTHERPTHR11645. P5CR. 1 hit.
PfamPF03807. F420_oxidored. 1 hit.
[Graphical view]
PIRSFPIRSF000193. Pyrrol-5-carb_rd. 1 hit.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMsTIGR00112. ProC. 1 hit.
PROSITEPS00521. P5CR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ12U91_METBU
AccessionPrimary (citable) accession number: Q12U91
Entry history
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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