Reviewed, UniProtKB/Swiss-Prot Q12T34 (UBIC_SHEDO)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase
      Short name=CL
      Short name=CPL
    EC=4.1.3.40

Gene names

Name:	ubiC
Ordered Locus Names:	Sden_0095

Organism

Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) [Complete proteome] [HAMAP]

Taxonomic identifier

318161 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity.
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 189	189	Probable chorismate--pyruvate lyase HAMAP MF_01632		PRO_0000292077
Sites
	Binding site	77	1	Substrate By similarity
	Binding site	115	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q12T34-1 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: B10F2355F3B04558	FASTA	189	21,375
	10 20 30 40 50 60 MKVTSLSFPY GESIQWFSPE RADSIQNAQL KDWLLATGSL TLKLKNLCND FEVKVLGEQL 70 80 90 100 110 120 TSPLATDTMI EETVWMREVL LCLDGTPWVF ARTLVPQSLL DFKSQAFTQL GNKPLGELLY 130 140 150 160 170 180 TSPEIIPGKI ELAKFDTCSR LAKLATSLKQ EISDPLWGRR RHFSIDTRHL TVSEIFLPAA VAHMKLHNK

References

[1]

"Complete sequence of Shewanella denitrificans OS217." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000302 Genomic DNA. Translation: ABE53392.1.
RefSeq	YP_561115.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4017159.
GenomeReviews	Gene locus Sden_0095 in contig CP000302_GR.
KEGG	sdn:Sden_0095.
NMPDR	fig|318161.14.peg.88.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q12T34.
OMA	Q12T34. WGRRSRF.
Enzyme and pathway databases
BioCyc	SDEN318161:SDEN_0095-MON.
Family and domain databases
HAMAP	MF_01632. [Tree]
InterPro	IPR007440. Chorismate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC_SHEDO

Accession

Primary (citable) accession number: Q12T34

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	August 22, 2006
Last modified:	June 16, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)