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Q12RC1 (Q12RC1_SHEDO) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Choline dehydrogenase HAMAP MF_00750
Short name=CDH HAMAP MF_00750
Short name=CHD HAMAP MF_00750
EC=1.1.99.1 HAMAP MF_00750
Gene names
Name:betA HAMAP MF_00750
Ordered Locus Names:Sden_0715
OrganismShewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) [Complete proteome] [HAMAP] EMBL ABE54005.1
Taxonomic identifier318161 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length572 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. HAMAP MF_00750 SAAS SAAS007867

Catalytic activity

Choline + acceptor = betaine aldehyde + reduced acceptor. HAMAP MF_00750 SAAS SAAS007867

Cofactor

FAD By similarity. HAMAP MF_00750 SAAS SAAS007867

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. HAMAP MF_00750 SAAS SAAS007867

Sequence similarities

Belongs to the GMC oxidoreductase family. HAMAP MF_00750

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding17 – 4630FAD By similarity HAMAP MF_00750

Sites

Active site4801 By similarity HAMAP MF_00750

Sequences

Sequence LengthMass (Da)Tools
Q12RC1 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 8548481482552ED0

FASTA57262,898
        10         20         30         40         50         60 
MTATMTTAIT TTKKKYDYII VGAGSAGCVL ANRLSEDPNN SVLLLETGGS DKSIFIQMPT 

        70         80         90        100        110        120 
ALSIPMNTPK YTWQFETDPE PYLDNRRMHC PRGKVLGGSS SINGMVYVRG HAHDFNEWQQ 

       130        140        150        160        170        180 
HGAEGWDYAH CLPYFKKAES WAFGGDDYRG DVGPLAVNNG NQMKNPLYQA FVDAGVDAGY 

       190        200        210        220        230        240 
LATADYNGAQ QEGFGPMHMT VKNGVRWSTA NAYLRPAMKR KNLTVVTHAL THKVLFEGKA 

       250        260        270        280        290        300 
AAGVRYERKG EMVDVFTTKE VILSAGSIGS PHLLQLSGVG EAKTLAAAGV DLVHELPGVG 

       310        320        330        340        350        360 
ENLQDHLEFY FQFKCTQPIS LNGQLGPLSK LKIGVQWILD KSGLGTTNHF ESCGFIRSKP 

       370        380        390        400        410        420 
DLAWPDLQYH FLPAAMRYDG KEAFAGHGFQ VHIGHNKPKS RGSVKISSSD PKVHPKILFN 

       430        440        450        460        470        480 
YLEHQDDIQG FRDCVRLTRE IINQPGLDAY RGEEIQPGMA VQTDEQIDTF VRQSVESAYH 

       490        500        510        520        530        540 
PSCSCKMGVD EMAVVDPQTR VHGVSGLRVV DSSIFPTIPN GNLNAPTIML AERAADLILG 

       550        560        570 
KTPLPASDAE VRLGADWQTK QRQNTPKRVF NN

« Hide

References

[1]"Complete sequence of Shewanella denitrificans OS217."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OS217 / ATCC BAA-1090 / DSM 15013.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000302 Genomic DNA. Translation: ABE54005.1.
RefSeqYP_561728.1. NC_007954.1.

3D structure databases

ProteinModelPortalQ12RC1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ12RC1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4016630.
GenomeReviewsGene locus Sden_0715 in contig CP000302_GR.
KEGGsdn:Sden_0715.
NMPDRfig|318161.14.peg.697.
PATRIC23487110. VBISheDen79529_0762.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2303.
HOGENOMHBG734713.
OMAHMTVKNG.
PhylomeDBQ12RC1.
ProtClustDBPRK02106.

Enzyme and pathway databases

BioCycSDEN318161:SDEN_0715-MONOMER.

Family and domain databases

HAMAPMF_00750. Choline_dehydrogen.
[Tree]
InterProIPR011533. Choline_dehydrogenase.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
KOK00108.
PfamPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFPIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsTIGR01810. BetA. 1 hit.
PROSITEPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ12RC1_SHEDO
AccessionPrimary (citable) accession number: Q12RC1
Entry history
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info