Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Na(+)-translocating NADH-quinone reductase subunit E

Gene

nqrE

Organism
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na+ ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.UniRule annotation

Catalytic activityi

NADH + ubiquinone + n Na+(In) = NAD+ + ubiquinol + n Na+(Out).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

NAD, Sodium, Ubiquinone

Enzyme and pathway databases

BioCyciSDEN318161:GHKQ-1018-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Na(+)-translocating NADH-quinone reductase subunit EUniRule annotation (EC:1.6.5.8UniRule annotation)
Short name:
Na(+)-NQR subunit EUniRule annotation
Short name:
Na(+)-translocating NQR subunit EUniRule annotation
Alternative name(s):
NQR complex subunit EUniRule annotation
NQR-1 subunit EUniRule annotation
Gene namesi
Name:nqrEUniRule annotation
Ordered Locus Names:Sden_0986
OrganismiShewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)
Taxonomic identifieri318161 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000001982 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei11 – 3121HelicalUniRule annotationAdd
BLAST
Transmembranei35 – 5521HelicalUniRule annotationAdd
BLAST
Transmembranei79 – 9921HelicalUniRule annotationAdd
BLAST
Transmembranei114 – 13421HelicalUniRule annotationAdd
BLAST
Transmembranei144 – 16421HelicalUniRule annotationAdd
BLAST
Transmembranei180 – 20021HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 202202Na(+)-translocating NADH-quinone reductase subunit EPRO_1000060217Add
BLAST

Interactioni

Subunit structurei

Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.UniRule annotation

Protein-protein interaction databases

STRINGi318161.Sden_0986.

Family & Domainsi

Sequence similaritiesi

Belongs to the NqrDE/RnfAE family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108IUB. Bacteria.
COG2209. LUCA.
HOGENOMiHOG000279324.
KOiK00350.
OMAiYFLGMCS.
OrthoDBiEOG6GBMG7.

Family and domain databases

HAMAPiMF_00429. NqrE.
InterProiIPR010967. NqrE.
IPR003667. Rnf-Nqr.
[Graphical view]
PANTHERiPTHR30335:SF1. PTHR30335:SF1. 1 hit.
PfamiPF02508. Rnf-Nqr. 1 hit.
[Graphical view]
PIRSFiPIRSF006102. NQR_DE. 1 hit.
TIGRFAMsiTIGR01940. nqrE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q12QK2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEHYISLLIR SVFIENMALS FFLGMCTFLA VSKKVTTAMG LGVAVIVVLA
60 70 80 90 100
ISVPANQIIY QGILAPGALA WAGVPDADLS FLKFITFIGV IAALVQILEM
110 120 130 140 150
TLDKYFPPLY NALGIFLPLI TVNCAIFGAV AFMVERDYNL TESLVFGVGS
160 170 180 190 200
GIGWALAIVL LAAVREKMKY SDVPNGLRGL GITFISAGLM ALGFMSFSGV

SL
Length:202
Mass (Da):21,555
Last modified:August 22, 2006 - v1
Checksum:iE48F9601BEB6DC51
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000302 Genomic DNA. Translation: ABE54274.1.
RefSeqiWP_011495438.1. NC_007954.1.

Genome annotation databases

EnsemblBacteriaiABE54274; ABE54274; Sden_0986.
KEGGisdn:Sden_0986.
PATRICi23487692. VBISheDen79529_1046.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000302 Genomic DNA. Translation: ABE54274.1.
RefSeqiWP_011495438.1. NC_007954.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi318161.Sden_0986.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE54274; ABE54274; Sden_0986.
KEGGisdn:Sden_0986.
PATRICi23487692. VBISheDen79529_1046.

Phylogenomic databases

eggNOGiENOG4108IUB. Bacteria.
COG2209. LUCA.
HOGENOMiHOG000279324.
KOiK00350.
OMAiYFLGMCS.
OrthoDBiEOG6GBMG7.

Enzyme and pathway databases

BioCyciSDEN318161:GHKQ-1018-MONOMER.

Family and domain databases

HAMAPiMF_00429. NqrE.
InterProiIPR010967. NqrE.
IPR003667. Rnf-Nqr.
[Graphical view]
PANTHERiPTHR30335:SF1. PTHR30335:SF1. 1 hit.
PfamiPF02508. Rnf-Nqr. 1 hit.
[Graphical view]
PIRSFiPIRSF006102. NQR_DE. 1 hit.
TIGRFAMsiTIGR01940. nqrE. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: OS217 / ATCC BAA-1090 / DSM 15013.

Entry informationi

Entry nameiNQRE_SHEDO
AccessioniPrimary (citable) accession number: Q12QK2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 22, 2006
Last modified: November 11, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.