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Q12NA7 (ASTE_SHEDO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Succinylglutamate desuccinylase

EC=3.5.1.96
Gene names
Name:astE
Ordered Locus Names:Sden_1785
OrganismShewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) [Complete proteome] [HAMAP]
Taxonomic identifier318161 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length348 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transforms N(2)-succinylglutamate into succinate and glutamate By similarity. HAMAP-Rule MF_00767

Catalytic activity

N-succinyl-L-glutamate + H2O = succinate + L-glutamate. HAMAP-Rule MF_00767

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00767

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 5/5. HAMAP-Rule MF_00767

Sequence similarities

Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 348348Succinylglutamate desuccinylase HAMAP-Rule MF_00767
PRO_0000262080

Sites

Active site2281 Potential
Metal binding671Zinc By similarity
Metal binding701Zinc By similarity
Metal binding1641Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
Q12NA7 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 3B18928CD9F64240

FASTA34839,197
        10         20         30         40         50         60 
MQHELMDNHD FLAFTLAHPH GIAQRFSFEL GQHTQVEVWD TGVIAFLPKE KYTAQAPKQV 

        70         80         90        100        110        120 
ILSCAVHGNE TAPIEICNRL ITELLTEKVQ AKHRTLFLIG NPPAIHNQTR FIEENMNRLF 

       130        140        150        160        170        180 
SGAHSKGEGL THAERIRAKA LEDYVAEFYL GAPSNEQRIH YDLHTAIRPS KHEKFAIYPY 

       190        200        210        220        230        240 
RPGRAYSGEQ IMFLAACGVD TILFHHEPTT TFSYYSSEQF NADAFTVELG KVMPFGQNDM 

       250        260        270        280        290        300 
SRFEQTQTML TKLVSGEALG LSAFSAEKVN LYKVCRSINK RFEDFAFNFA DQAENFSAFT 

       310        320        330        340 
KGEVLATEGG EQVLVEQPQE AIVFPNAKVP VGQRTVLCLV PAPNENIR 

« Hide

References

[1]"Complete sequence of Shewanella denitrificans OS217."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OS217 / ATCC BAA-1090 / DSM 15013.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000302 Genomic DNA. Translation: ABE55069.1.
RefSeqYP_562792.1. NC_007954.1.

3D structure databases

ProteinModelPortalQ12NA7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING318161.Sden_1785.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE55069; ABE55069; Sden_1785.
GeneID4018264.
KEGGsdn:Sden_1785.
PATRIC23489447. VBISheDen79529_1896.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2988.
HOGENOMHOG000280300.
KOK05526.
OMATAPIEIC.
OrthoDBEOG613070.
ProtClustDBPRK05324.

Enzyme and pathway databases

BioCycSDEN318161:GHKQ-1848-MONOMER.
UniPathwayUPA00185; UER00283.

Family and domain databases

HAMAPMF_00767. Arg_catab_AstE.
InterProIPR007036. Aste_AspA.
IPR016681. SuccinylGlu_desuccinylase.
[Graphical view]
PfamPF04952. AstE_AspA. 1 hit.
[Graphical view]
PIRSFPIRSF017020. AstE. 1 hit.
TIGRFAMsTIGR03242. arg_catab_astE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameASTE_SHEDO
AccessionPrimary (citable) accession number: Q12NA7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: August 22, 2006
Last modified: February 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways