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Q12NA7

- ASTE_SHEDO

UniProt

Q12NA7 - ASTE_SHEDO

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Protein
Succinylglutamate desuccinylase
Gene
astE, Sden_1785
Organism
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Transforms N(2)-succinylglutamate into succinate and glutamate By similarity.UniRule annotation

Catalytic activityi

N-succinyl-L-glutamate + H2O = succinate + L-glutamate.UniRule annotation

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi67 – 671Zinc By similarity
Metal bindingi70 – 701Zinc By similarity
Metal bindingi164 – 1641Zinc By similarity
Active sitei228 – 2281 Reviewed prediction

GO - Molecular functioni

  1. hydrolase activity, acting on ester bonds Source: UniProtKB-HAMAP
  2. succinylglutamate desuccinylase activity Source: UniProtKB-EC
  3. zinc ion binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. arginine catabolic process to glutamate Source: UniProtKB-HAMAP
  2. arginine catabolic process to succinate Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Arginine metabolism

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciSDEN318161:GHKQ-1848-MONOMER.
UniPathwayiUPA00185; UER00283.

Names & Taxonomyi

Protein namesi
Recommended name:
Succinylglutamate desuccinylase (EC:3.5.1.96)
Gene namesi
Name:astE
Ordered Locus Names:Sden_1785
OrganismiShewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)
Taxonomic identifieri318161 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000001982: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 348348Succinylglutamate desuccinylaseUniRule annotation
PRO_0000262080Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi318161.Sden_1785.

Structurei

3D structure databases

ProteinModelPortaliQ12NA7.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2988.
HOGENOMiHOG000280300.
KOiK05526.
OMAiTAPIEIC.
OrthoDBiEOG613070.

Family and domain databases

HAMAPiMF_00767. Arg_catab_AstE.
InterProiIPR007036. Aste_AspA.
IPR016681. SuccinylGlu_desuccinylase.
[Graphical view]
PfamiPF04952. AstE_AspA. 1 hit.
[Graphical view]
PIRSFiPIRSF017020. AstE. 1 hit.
TIGRFAMsiTIGR03242. arg_catab_astE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q12NA7-1 [UniParc]FASTAAdd to Basket

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MQHELMDNHD FLAFTLAHPH GIAQRFSFEL GQHTQVEVWD TGVIAFLPKE    50
KYTAQAPKQV ILSCAVHGNE TAPIEICNRL ITELLTEKVQ AKHRTLFLIG 100
NPPAIHNQTR FIEENMNRLF SGAHSKGEGL THAERIRAKA LEDYVAEFYL 150
GAPSNEQRIH YDLHTAIRPS KHEKFAIYPY RPGRAYSGEQ IMFLAACGVD 200
TILFHHEPTT TFSYYSSEQF NADAFTVELG KVMPFGQNDM SRFEQTQTML 250
TKLVSGEALG LSAFSAEKVN LYKVCRSINK RFEDFAFNFA DQAENFSAFT 300
KGEVLATEGG EQVLVEQPQE AIVFPNAKVP VGQRTVLCLV PAPNENIR 348
Length:348
Mass (Da):39,197
Last modified:August 22, 2006 - v1
Checksum:i3B18928CD9F64240
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000302 Genomic DNA. Translation: ABE55069.1.
RefSeqiWP_011496226.1. NC_007954.1.
YP_562792.1. NC_007954.1.

Genome annotation databases

EnsemblBacteriaiABE55069; ABE55069; Sden_1785.
GeneIDi4018264.
KEGGisdn:Sden_1785.
PATRICi23489447. VBISheDen79529_1896.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000302 Genomic DNA. Translation: ABE55069.1 .
RefSeqi WP_011496226.1. NC_007954.1.
YP_562792.1. NC_007954.1.

3D structure databases

ProteinModelPortali Q12NA7.
ModBasei Search...

Protein-protein interaction databases

STRINGi 318161.Sden_1785.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE55069 ; ABE55069 ; Sden_1785 .
GeneIDi 4018264.
KEGGi sdn:Sden_1785.
PATRICi 23489447. VBISheDen79529_1896.

Phylogenomic databases

eggNOGi COG2988.
HOGENOMi HOG000280300.
KOi K05526.
OMAi TAPIEIC.
OrthoDBi EOG613070.

Enzyme and pathway databases

UniPathwayi UPA00185 ; UER00283 .
BioCyci SDEN318161:GHKQ-1848-MONOMER.

Family and domain databases

HAMAPi MF_00767. Arg_catab_AstE.
InterProi IPR007036. Aste_AspA.
IPR016681. SuccinylGlu_desuccinylase.
[Graphical view ]
Pfami PF04952. AstE_AspA. 1 hit.
[Graphical view ]
PIRSFi PIRSF017020. AstE. 1 hit.
TIGRFAMsi TIGR03242. arg_catab_astE. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: OS217 / ATCC BAA-1090 / DSM 15013.

Entry informationi

Entry nameiASTE_SHEDO
AccessioniPrimary (citable) accession number: Q12NA7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: August 22, 2006
Last modified: September 3, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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