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Q12LV8 (Q12LV8_SHEDO) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cytidine deaminase HAMAP MF_01558 PIRNR PIRNR006334
EC=3.5.4.5 HAMAP MF_01558 PIRNR PIRNR006334
Alternative name(s):
Cytidine aminohydrolase HAMAP MF_01558
Gene names
Name:cdd HAMAP MF_01558
Ordered Locus Names:Sden_2288
OrganismShewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) [Complete proteome] [HAMAP] EMBL ABE55568.1
Taxonomic identifier318161 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis By similarity. HAMAP MF_01558 SAAS SAAS002125

Catalytic activity

Cytidine + H2O = uridine + NH3. HAMAP MF_01558 PIRNR PIRNR006334 SAAS SAAS002125

Cofactor

Binds 1 zinc ion By similarity. HAMAP MF_01558 PIRSR PIRSR006334-3 PIRNR PIRNR006334 SAAS SAAS002125

Subunit structure

Homodimer By similarity. HAMAP MF_01558 SAAS SAAS002125

Sequence similarities

Belongs to the cytidine and deoxycytidylate deaminase family. HAMAP MF_01558 PIRNR PIRNR006334

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region88 – 903Substrate binding By similarity HAMAP MF_01558 PIRSR PIRSR006334-2

Sites

Active site1031Proton donor By similarity HAMAP MF_01558 PIRSR PIRSR006334-1
Metal binding1011Zinc; catalytic By similarity HAMAP MF_01558 PIRSR PIRSR006334-3
Metal binding1281Zinc; catalytic By similarity HAMAP MF_01558 PIRSR PIRSR006334-3
Metal binding1311Zinc; catalytic By similarity HAMAP MF_01558 PIRSR PIRSR006334-3

Sequences

Sequence LengthMass (Da)Tools
Q12LV8 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: CE6C4199D6AA2173

FASTA29732,261
        10         20         30         40         50         60 
MQNRFINSIT QLPKPLANAL IPLLQQEFCG HIDAHQVAEL KKASGLAEAD LLLALLPIAA 

        70         80         90        100        110        120 
SLANPSISEF YVGAIAKGSS GDIYMGANLE LPNEALFHSV HAEQSAISHA WLSGETKIVD 

       130        140        150        160        170        180 
IVVNFSPCGH CRQFMNELVE GSLVRIHLPQ QEIKPLSHYL PYAFGPSDLN VTTPLLSKSE 

       190        200        210        220        230        240 
VELALNSDDP MIIEALDQAG LSYAPYTQSY AAVVLETKDG KTYCGRYAEN AAFNPSMLPM 

       250        260        270        280        290 
QMALSNLMRH DKQFSDIKRA VLVESSKGKI SLVSATMDAL HAVAAVELEH IVVEPQI

« Hide

References

[1]"Complete sequence of Shewanella denitrificans OS217."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OS217 / ATCC BAA-1090 / DSM 15013.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000302 Genomic DNA. Translation: ABE55568.1.
RefSeqYP_563291.1. NC_007954.1.

3D structure databases

ProteinModelPortalQ12LV8.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ12LV8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4018780.
GenomeReviewsGene locus Sden_2288 in contig CP000302_GR.
KEGGsdn:Sden_2288.
NMPDRfig|318161.14.peg.2229.
PATRIC23490495. VBISheDen79529_2407.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0295.
HOGENOMHBG591160.
OMANRSHAPY.
PhylomeDBQ12LV8.
ProtClustDBPRK09027.

Enzyme and pathway databases

BioCycSDEN318161:SDEN_2288-MONOMER.

Family and domain databases

HAMAPMF_01558. Cyt_deam.
[Tree]
InterProIPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR013171. Cyd/dCyd_deaminase_Zn-bd.
IPR006263. Cyt_deam_dimer.
IPR016193. Cytidine_deaminase-like.
IPR020797. Cytidine_deaminase_bacteria.
[Graphical view]
KOK01489.
PANTHERPTHR11644:SF12. PTHR11644:SF12. 1 hit.
PfamPF00383. dCMP_cyt_deam_1. 1 hit.
PF08211. dCMP_cyt_deam_2. 1 hit.
[Graphical view]
PIRSFPIRSF006334. Cdd_plus_pseudo. 1 hit.
SUPFAMSSF53927. Cytidine_deaminase-like. 2 hits.
PROSITEPS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ12LV8_SHEDO
AccessionPrimary (citable) accession number: Q12LV8
Entry history
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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