Reviewed,
UniProtKB/Swiss-Prot Q12LR7 (ASTB_SHEDO)
Last modified
June 16, 2009.
Version 24.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: N-succinylarginine dihydrolase EC=3.5.3.23 | ||||
| Gene names |
| ||||
| Organism | Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 318161 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella |
Protein attributes
| Sequence length | 444 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO2 By similarity. |
| Catalytic activity | N(2)-succinyl-L-arginine + 2 H2O = N(2)-succinyl-L-ornithine + 2 NH3 + CO2. HAMAP MF_01172 |
| Pathway | Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5. HAMAP MF_01172 |
| Subunit structure | Homodimer By similarity. |
| Sequence similarities | Belongs to the succinylarginine dihydrolase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Arginine metabolism |
| Molecular function | Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | arginine catabolic process to glutamate Inferred from electronic annotation. Source: HAMAP |
| Molecular function | N-succinylarginine dihydrolase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 444 | 444 | N-succinylarginine dihydrolase HAMAP MF_01172 | PRO_0000262374 | |||||
Regions | |||||||||
| Region | 19 – 28 | 10 | Substrate binding By similarity | ||||||
| Region | 137 – 138 | 2 | Substrate binding By similarity | ||||||
Sites | |||||||||
| Active site | 174 | 1 | By similarity | ||||||
| Active site | 250 | 1 | By similarity | ||||||
| Active site | 368 | 1 | Nucleophile By similarity | ||||||
| Binding site | 110 | 1 | Substrate By similarity | ||||||
| Binding site | 214 | 1 | Substrate By similarity | ||||||
| Binding site | 252 | 1 | Substrate By similarity | ||||||
| Binding site | 362 | 1 | Substrate By similarity | ||||||
Sequences
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References
| [1] | "Complete sequence of Shewanella denitrificans OS217." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J. Richardson P.Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CP000302 Genomic DNA. Translation: ABE55609.1. | |
| RefSeq | YP_563332.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 4018822. |
| GenomeReviews | Gene locus Sden_2329 in contig CP000302_GR. |
| KEGG | sdn:Sden_2329. |
| NMPDR | fig|318161.14.peg.2269. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q12LR7. |
| OMA | Q12LR7. KMKALME. |
Enzyme and pathway databases | |
| BioCyc | SDEN318161:SDEN_2329-MON. |
Family and domain databases | |
| HAMAP | MF_01172. [Tree] |
| InterPro | IPR007079. SuccinylArg_d-Hdrlase_AstB. [Graphical view] |
| Gene3D | G3DSA:3.75.10.20. SuccinylArg_di_hydro. 1 hit. |
| Pfam | PF04996. AstB. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR03241. arg_catab_astB. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | ASTB_SHEDO | ||||||||
| Accession | Primary (citable) accession number: Q12LR7 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


