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Protein

50S ribosomal protein L3

Gene

rplC

Organism
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciPSP296591:GHI4-977-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L3UniRule annotation
Gene namesi
Name:rplCUniRule annotation
Ordered Locus Names:Bpro_0256
OrganismiPolaromonas sp. (strain JS666 / ATCC BAA-500)
Taxonomic identifieri296591 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaePolaromonas
ProteomesiUP000001983 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 22722750S ribosomal protein L3PRO_1000052105Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei158 – 1581N5-methylglutamineUniRule annotation

Post-translational modificationi

Methylated by PrmB.UniRule annotation

Keywords - PTMi

Methylation

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.UniRule annotation

Protein-protein interaction databases

STRINGi296591.Bpro_0256.

Structurei

3D structure databases

ProteinModelPortaliQ12GX1.
SMRiQ12GX1. Positions 7-217.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L3P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0087.
HOGENOMiHOG000100368.
KOiK02906.
OMAiKRMAGRY.
OrthoDBiEOG6WDSMH.

Family and domain databases

HAMAPiMF_01325_B. Ribosomal_L3_B.
InterProiIPR000597. Ribosomal_L3.
IPR019927. Ribosomal_L3_bac/org-type.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PANTHERiPTHR11229. PTHR11229. 1 hit.
PfamiPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
TIGRFAMsiTIGR03625. L3_bact. 1 hit.
PROSITEiPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q12GX1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSNSLGLL GRKVGMMRLF TDDGDTVPVT VVDVSNNRVT QVKTEANDGY
60 70 80 90 100
DALQVAFGAR KASRVTKPAA GHLAKAGVEA GEILKEFRVT ADVAGKYAAG
110 120 130 140 150
TVVPAADVFA VGQLVDVQGT SIGKGYAGTI KRHNMSSQRA SHGNSRSHNV
160 170 180 190 200
PGSIGMAQDP GRVFPGKRMT GHLGDVTVTT QNLNIVRIDE ARQLLMIRGA
210 220
VPGSKGGFVT VRAAIKAKPT TAAKGAN
Length:227
Mass (Da):23,593
Last modified:August 21, 2006 - v1
Checksum:iDF94AEE75517A87C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000316 Genomic DNA. Translation: ABE42221.1.
RefSeqiWP_011481229.1. NC_007948.1.
YP_547119.1. NC_007948.1.

Genome annotation databases

EnsemblBacteriaiABE42221; ABE42221; Bpro_0256.
KEGGipol:Bpro_0256.
PATRICi22953564. VBIPolSp102244_0271.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000316 Genomic DNA. Translation: ABE42221.1.
RefSeqiWP_011481229.1. NC_007948.1.
YP_547119.1. NC_007948.1.

3D structure databases

ProteinModelPortaliQ12GX1.
SMRiQ12GX1. Positions 7-217.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi296591.Bpro_0256.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE42221; ABE42221; Bpro_0256.
KEGGipol:Bpro_0256.
PATRICi22953564. VBIPolSp102244_0271.

Phylogenomic databases

eggNOGiCOG0087.
HOGENOMiHOG000100368.
KOiK02906.
OMAiKRMAGRY.
OrthoDBiEOG6WDSMH.

Enzyme and pathway databases

BioCyciPSP296591:GHI4-977-MONOMER.

Family and domain databases

HAMAPiMF_01325_B. Ribosomal_L3_B.
InterProiIPR000597. Ribosomal_L3.
IPR019927. Ribosomal_L3_bac/org-type.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PANTHERiPTHR11229. PTHR11229. 1 hit.
PfamiPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
TIGRFAMsiTIGR03625. L3_bact. 1 hit.
PROSITEiPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JS666 / ATCC BAA-500.

Entry informationi

Entry nameiRL3_POLSJ
AccessioniPrimary (citable) accession number: Q12GX1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 14, 2008
Last sequence update: August 21, 2006
Last modified: March 31, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.