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Q12GA3 (Q12GA3_POLSJ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroline-5-carboxylate reductase RuleBase RU003903
EC=1.5.1.2 RuleBase RU003903
Gene names
Ordered Locus Names:Bpro_0475
OrganismPolaromonas sp. (strain JS666 / ATCC BAA-500) [Complete proteome] [HAMAP]
Taxonomic identifier296591 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Polaromonas

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H. RuleBase RU003903

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1. RuleBase RU003903

Sequence similarities

Belongs to the pyrroline-5-carboxylate reductase family. RuleBase RU003903

Sequences

Sequence LengthMass (Da)Tools
Q12GA3 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 608CAEDC0ECAC884

FASTA27828,905
        10         20         30         40         50         60 
MSTPNPGSNE HIAFIGGGNM ASAVIGGLLK QGLPAGQIQV VEPFAEQRAR LVQQFGVAVS 

        70         80         90        100        110        120 
DAPGASLSSA GLVVWAVKPQ TFKEAAAQAR AHTQAALHLS VAAGIRSDSI AQWLGTERVV 

       130        140        150        160        170        180 
RSMPNTPALV GKGMTALFAR PAATAADRAA VERVIQTTGE YLWLNDEVQL DAVTALSGSG 

       190        200        210        220        230        240 
PAYVFYFLEA MIQAGTDMGL EPEQARKLAV GTFVGASALA HASDEPLEVL RARVTSKGGT 

       250        260        270 
TYAALTSMEQ AGIKQQFMQA IEAARQRAGE LGDEFGAA

« Hide

References

[1]"Complete sequence of chromosome of Polaromonas sp. JS666."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Richardson P.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JS666 / ATCC BAA-500.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000316 Genomic DNA. Translation: ABE42439.1.
RefSeqYP_547337.1. NC_007948.1.

3D structure databases

ProteinModelPortalQ12GA3.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ12GA3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4011498.
GenomeReviewsGene locus Bpro_0475 in contig CP000316_GR.
KEGGpol:Bpro_0475.
NMPDRfig|296591.1.peg.4474.
PATRIC22953996. VBIPolSp102244_0485.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0345.
HOGENOMHBG726602.
OMARYLGGTR.
PhylomeDBQ12GA3.
ProtClustDBCLSK951795.

Enzyme and pathway databases

BioCycPSP296591:BPRO_0475-MONOMER.

Family and domain databases

InterProIPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR004455. NADP_OxRdtase_F420.
IPR000304. Pyrroline-COOH_reductase.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00286.
PANTHERPTHR11645. P5CR. 1 hit.
PfamPF03807. F420_oxidored. 1 hit.
[Graphical view]
PIRSFPIRSF000193. Pyrrol-5-carb_rd. 1 hit.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMsTIGR00112. ProC. 1 hit.
PROSITEPS00521. P5CR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ12GA3_POLSJ
AccessionPrimary (citable) accession number: Q12GA3
Entry history
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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