Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q12G50

- Q12G50_POLSJ

UniProt

Q12G50 - Q12G50_POLSJ

Protein
Submitted name:

Haloacid dehalogenase, type II

Gene

Bpro_0530

Organism
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (22 Aug 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi1 – 11NickelImported
    Metal bindingi2 – 21Nickel; via pros nitrogenImported

    GO - Molecular functioni

    1. (S)-2-haloacid dehalogenase activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    Keywords - Molecular functioni

    HydrolaseImported

    Enzyme and pathway databases

    BioCyciPSP296591:GHI4-1251-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Haloacid dehalogenase, type IIImported (EC:3.8.1.2Imported)
    Gene namesi
    Ordered Locus Names:Bpro_0530Imported
    OrganismiPolaromonas sp. (strain JS666 / ATCC BAA-500)Imported
    Taxonomic identifieri296591 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaePolaromonas
    ProteomesiUP000001983: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi296591.Bpro_0530.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3UM9X-ray2.19A/B1-229[»]
    ProteinModelPortaliQ12G50.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG1011.
    HOGENOMiHOG000248342.
    KOiK01560.
    OMAiREIVIAM.
    OrthoDBiEOG615VH2.

    Family and domain databases

    Gene3Di1.10.150.240. 1 hit.
    3.40.50.1000. 1 hit.
    InterProiIPR023214. HAD-like_dom.
    IPR006439. HAD-SF_hydro_IA.
    IPR006328. HAD_II.
    IPR023198. PGP_dom2.
    [Graphical view]
    PfamiPF13419. HAD_2. 1 hit.
    [Graphical view]
    PRINTSiPR00413. HADHALOGNASE.
    SUPFAMiSSF56784. SSF56784. 1 hit.
    TIGRFAMsiTIGR01493. HAD-SF-IA-v2. 1 hit.
    TIGR01428. HAD_type_II. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q12G50-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHAIKAVVFD LYGTLYDVYS VRTSCERIFP GQGEMVSKMW RQKQLEYTWM    50
    RTLMGQYQDF ESATLDALRY TCGSLGLALD ADGEAHLCSE YLSLTPFADV 100
    PQALQQLRAA GLKTAILSNG SRHSIRQVVG NSGLTNSFDH LISVDEVRLF 150
    KPHQKVYELA MDTLHLGESE ILFVSCNSWD ATGAKYFGYP VCWINRSNGV 200
    FDQLGVVPDI VVSDVGVLAS RFSPVDEAA 229
    Length:229
    Mass (Da):25,447
    Last modified:August 22, 2006 - v1
    Checksum:i21525491C306A94F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000316 Genomic DNA. Translation: ABE42492.1.
    RefSeqiWP_011481495.1. NC_007948.1.
    YP_547390.1. NC_007948.1.

    Genome annotation databases

    EnsemblBacteriaiABE42492; ABE42492; Bpro_0530.
    GeneIDi4011399.
    KEGGipol:Bpro_0530.
    PATRICi22954108. VBIPolSp102244_0541.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000316 Genomic DNA. Translation: ABE42492.1 .
    RefSeqi WP_011481495.1. NC_007948.1.
    YP_547390.1. NC_007948.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3UM9 X-ray 2.19 A/B 1-229 [» ]
    ProteinModelPortali Q12G50.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 296591.Bpro_0530.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABE42492 ; ABE42492 ; Bpro_0530 .
    GeneIDi 4011399.
    KEGGi pol:Bpro_0530.
    PATRICi 22954108. VBIPolSp102244_0541.

    Phylogenomic databases

    eggNOGi COG1011.
    HOGENOMi HOG000248342.
    KOi K01560.
    OMAi REIVIAM.
    OrthoDBi EOG615VH2.

    Enzyme and pathway databases

    BioCyci PSP296591:GHI4-1251-MONOMER.

    Family and domain databases

    Gene3Di 1.10.150.240. 1 hit.
    3.40.50.1000. 1 hit.
    InterProi IPR023214. HAD-like_dom.
    IPR006439. HAD-SF_hydro_IA.
    IPR006328. HAD_II.
    IPR023198. PGP_dom2.
    [Graphical view ]
    Pfami PF13419. HAD_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00413. HADHALOGNASE.
    SUPFAMi SSF56784. SSF56784. 1 hit.
    TIGRFAMsi TIGR01493. HAD-SF-IA-v2. 1 hit.
    TIGR01428. HAD_type_II. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JS666 / ATCC BAA-500Imported.
    2. "Structural adaptations of L-2-haloacid dehalogenases that enable hydrolytic defluorination."
      Chan P.W.Y., To T.K.W., Petit P., Tran C., Waelti M., Savchenko A., Yakunin A.F., Edwards E.A., Pai E.F.
      Submitted (NOV-2011) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.19 ANGSTROMS).

    Entry informationi

    Entry nameiQ12G50_POLSJ
    AccessioniPrimary (citable) accession number: Q12G50
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 22, 2006
    Last sequence update: August 22, 2006
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3