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Q12G50

- Q12G50_POLSJ

UniProt

Q12G50 - Q12G50_POLSJ

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Protein
Submitted name: Haloacid dehalogenase, type II
Gene
Bpro_0530
Organism
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi1 – 11NickelImported
Metal bindingi2 – 21Nickel; via pros nitrogenImported

GO - Molecular functioni

  1. (S)-2-haloacid dehalogenase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Keywords - Ligandi

Metal-bindingImported, NickelImported

Enzyme and pathway databases

BioCyciPSP296591:GHI4-1251-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Haloacid dehalogenase, type IIImported (EC:3.8.1.2Imported)
Gene namesi
Ordered Locus Names:Bpro_0530Imported
OrganismiPolaromonas sp. (strain JS666 / ATCC BAA-500)Imported
Taxonomic identifieri296591 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaePolaromonas
ProteomesiUP000001983: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi296591.Bpro_0530.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3UM9X-ray2.19A/B1-229[»]
ProteinModelPortaliQ12G50.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1011.
HOGENOMiHOG000248342.
KOiK01560.
OMAiREIVIAM.
OrthoDBiEOG615VH2.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 1 hit.
InterProiIPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR006328. HAD_II.
IPR023198. PGP_dom2.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
PRINTSiPR00413. HADHALOGNASE.
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01493. HAD-SF-IA-v2. 1 hit.
TIGR01428. HAD_type_II. 1 hit.

Sequencei

Sequence statusi: Complete.

Q12G50-1 [UniParc]FASTAAdd to Basket

« Hide

MHAIKAVVFD LYGTLYDVYS VRTSCERIFP GQGEMVSKMW RQKQLEYTWM    50
RTLMGQYQDF ESATLDALRY TCGSLGLALD ADGEAHLCSE YLSLTPFADV 100
PQALQQLRAA GLKTAILSNG SRHSIRQVVG NSGLTNSFDH LISVDEVRLF 150
KPHQKVYELA MDTLHLGESE ILFVSCNSWD ATGAKYFGYP VCWINRSNGV 200
FDQLGVVPDI VVSDVGVLAS RFSPVDEAA 229
Length:229
Mass (Da):25,447
Last modified:August 22, 2006 - v1
Checksum:i21525491C306A94F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000316 Genomic DNA. Translation: ABE42492.1.
RefSeqiWP_011481495.1. NC_007948.1.
YP_547390.1. NC_007948.1.

Genome annotation databases

EnsemblBacteriaiABE42492; ABE42492; Bpro_0530.
GeneIDi4011399.
KEGGipol:Bpro_0530.
PATRICi22954108. VBIPolSp102244_0541.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000316 Genomic DNA. Translation: ABE42492.1 .
RefSeqi WP_011481495.1. NC_007948.1.
YP_547390.1. NC_007948.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3UM9 X-ray 2.19 A/B 1-229 [» ]
ProteinModelPortali Q12G50.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 296591.Bpro_0530.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE42492 ; ABE42492 ; Bpro_0530 .
GeneIDi 4011399.
KEGGi pol:Bpro_0530.
PATRICi 22954108. VBIPolSp102244_0541.

Phylogenomic databases

eggNOGi COG1011.
HOGENOMi HOG000248342.
KOi K01560.
OMAi REIVIAM.
OrthoDBi EOG615VH2.

Enzyme and pathway databases

BioCyci PSP296591:GHI4-1251-MONOMER.

Family and domain databases

Gene3Di 1.10.150.240. 1 hit.
3.40.50.1000. 1 hit.
InterProi IPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR006328. HAD_II.
IPR023198. PGP_dom2.
[Graphical view ]
Pfami PF13419. HAD_2. 1 hit.
[Graphical view ]
PRINTSi PR00413. HADHALOGNASE.
SUPFAMi SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR01493. HAD-SF-IA-v2. 1 hit.
TIGR01428. HAD_type_II. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JS666 / ATCC BAA-500.
  2. "Structural adaptations of L-2-haloacid dehalogenases that enable hydrolytic defluorination."
    Chan P.W.Y., To T.K.W., Petit P., Tran C., Waelti M., Savchenko A., Yakunin A.F., Edwards E.A., Pai E.F.
    Submitted (NOV-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.19 ANGSTROMS) IN COMPLEX WITH NICKEL.

Entry informationi

Entry nameiQ12G50_POLSJ
AccessioniPrimary (citable) accession number: Q12G50
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: September 3, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

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