Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative thymidine phosphorylase

Gene

Bpro_1194

Organism
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciPSP296591:G1G6E-1203-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPaseUniRule annotation
Gene namesi
Ordered Locus Names:Bpro_1194
OrganismiPolaromonas sp. (strain JS666 / ATCC BAA-500)
Taxonomic identifieri296591 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaePolaromonas
Proteomesi
  • UP000001983 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003147061 – 511Putative thymidine phosphorylaseAdd BLAST511

Interactioni

Protein-protein interaction databases

STRINGi296591.Bpro_1194

Structurei

3D structure databases

SMRiQ12E97
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMW Bacteria
COG0213 LUCA
HOGENOMiHOG000252767
KOiK00758
OMAiQMVASIM
OrthoDBiPOG091H02BC

Family and domain databases

Gene3Di3.40.1030.10, 2 hits
3.90.1170.30, 1 hit
HAMAPiMF_00703 Thymid_phosp_2, 1 hit
InterProiView protein in InterPro
IPR000312 Glycosyl_Trfase_fam3
IPR017459 Glycosyl_Trfase_fam3_N_dom
IPR036320 Glycosyl_Trfase_fam3_N_dom)sf
IPR035902 Nuc_phospho_transferase
IPR036566 PYNP-like_C_sf
IPR013102 PYNP_C
IPR017872 Pyrmidine_PPase_CS
IPR028579 Thym_Pase_Put
IPR013466 Thymidine/AMP_Pase
IPR000053 Thymidine/pyrmidine_PPase
PANTHERiPTHR10515 PTHR10515, 1 hit
PfamiView protein in Pfam
PF02885 Glycos_trans_3N, 1 hit
PF00591 Glycos_transf_3, 1 hit
PF07831 PYNP_C, 1 hit
PIRSFiPIRSF000478 TP_PyNP, 1 hit
SMARTiView protein in SMART
SM00941 PYNP_C, 1 hit
SUPFAMiSSF47648 SSF47648, 1 hit
SSF52418 SSF52418, 1 hit
SSF54680 SSF54680, 1 hit
TIGRFAMsiTIGR02645 ARCH_P_rylase, 1 hit
PROSITEiView protein in PROSITE
PS00647 THYMID_PHOSPHORYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q12E97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTPPTPLSS LTPHKLRLRR LGIDTYQEPV LYMHRDCRVC HSEGFEAQSR
60 70 80 90 100
VELALGDRTI VATLNVVSGD FLAPDEAGLS EAAWRLLGAQ EGDMVSPRHP
110 120 130 140 150
APIESLGHVR AKVYGRHLTQ AAITAVIEDV TAGRYSDLQL AAFVTACAGD
160 170 180 190 200
RLDQEETVSL TRAMVAAGER IDWGEGLVMD KHCVGGLPGN RTTMVIVPIV
210 220 230 240 250
AACGLRMPKT SSRAITSPAG TADTMETLAP VDLDVAQIRR VVERTGGCVV
260 270 280 290 300
WGGAVRLSPA DDILIRVERP LDLDSQGQLV ASILSKKVAA GSTHVLIDMP
310 320 330 340 350
VGPTAKVRSA EAADLLGRLL GQVGQTLGLR MRVVQTDGLA PVGRGIGPAL
360 370 380 390 400
EARDVLAVLR NLATAPADLA QRSLLLAGEV LEFGGAAPAG GGLALASAVL
410 420 430 440 450
ADGRAWRKFQ DICAAQGGLR EPPVAAHQQA VHALRSGSVL AIDNRRLARI
460 470 480 490 500
AKLAGAPGAA CAGIDLHVRP GEFVERGQPL FTLHAATPGE LAYALEYAAS
510
QAETVHVLED A
Length:511
Mass (Da):53,699
Last modified:August 22, 2006 - v1
Checksum:i39A4B6625FA46595
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000316 Genomic DNA Translation: ABE43145.1
RefSeqiWP_011482146.1, NC_007948.1

Genome annotation databases

EnsemblBacteriaiABE43145; ABE43145; Bpro_1194
KEGGipol:Bpro_1194

Similar proteinsi

Entry informationi

Entry nameiTYPH_POLSJ
AccessioniPrimary (citable) accession number: Q12E97
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 22, 2006
Last modified: March 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health