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Q12CW0 (Q12CW0_POLSJ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histidinol-phosphate aminotransferase 2 HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023
Alternative name(s):
Imidazole acetol-phosphate transaminase 2 HAMAP MF_01023
Gene names
Name:hisC2 HAMAP MF_01023
Ordered Locus Names:Bpro_1696
OrganismPolaromonas sp. (strain JS666 / ATCC BAA-500) [Complete proteome] [HAMAP]
Taxonomic identifier296591 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Polaromonas

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861

Subunit structure

Homodimer By similarity. HAMAP MF_01023

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2131N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

Sequence LengthMass (Da)Tools
Q12CW0 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: D8D17B28F7D02253

FASTA35638,858
        10         20         30         40         50         60 
MNSSQSFWSP VVRDLVPYTP GEQPNIAGLI KLNTNENPYP PSPAAVRAIA ATAQDGLQLY 

        70         80         90        100        110        120 
PDPQATSLRQ AIAAYHGIDA AQVFPGNGSD EVLAHAFFAF FQQDQPILMP DITYSFYKVY 

       130        140        150        160        170        180 
CGLYGIAFEV VPLDAAMRIQ VADYQRACGG VVIANPNAPT GTGLPLAQIE KLLQQHSRRT 

       190        200        210        220        230        240 
VLVDEAYVDF GGESAIGLID RYPNLLVVHT LSKSRSLAGL RVGFAAGQRH LIEALERVKD 

       250        260        270        280        290        300 
SFNSYPLDRL AIAGAVAAYE DRAHFEKTRA AVMQSRELLS RQLQALGFEV LPSQANFLMA 

       310        320        330        340        350 
RHGQYDAAAL AARLREKGIL ARHFKLPRIE QYLRISVGTP LQCEALVGAL RVLLAA

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References

[1]"Complete sequence of chromosome of Polaromonas sp. JS666."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Richardson P.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JS666 / ATCC BAA-500.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000316 Genomic DNA. Translation: ABE43632.1.
RefSeqYP_548530.1. NC_007948.1.

3D structure databases

ProteinModelPortalQ12CW0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ12CW0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4015676.
GenomeReviewsGene locus Bpro_1696 in contig CP000316_GR.
KEGGpol:Bpro_1696.
NMPDRfig|296591.1.peg.2384.
PATRIC22956485. VBIPolSp102244_1715.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0079.
HOGENOMHBG646350.
OMAHFKQARI.
ProtClustDBPRK05387.

Enzyme and pathway databases

BioCycPSP296591:BPRO_1696-MONOMER.

Family and domain databases

HAMAPMF_01023. HisC_aminotrans_2.
[Tree]
InterProIPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00817.
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01141. HisC. 1 hit.
PROSITEPS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ12CW0_POLSJ
AccessionPrimary (citable) accession number: Q12CW0
Entry history
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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