ID   HEM6_POLSJ              Reviewed;         308 AA.
AC   Q12C42;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Coproporphyrinogen-III oxidase, aerobic;
DE            Short=Coproporphyrinogenase;
DE            Short=Coprogen oxidase;
DE            EC=1.3.3.3;
GN   Name=hemF; OrderedLocusNames=Bpro_1970;
OS   Polaromonas sp. (strain JS666 / ATCC BAA-500).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Polaromonas.
OX   NCBI_TaxID=296591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C.,
RA   Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Anderson I., Richardson P.;
RT   "Complete sequence of chromosome of Polaromonas sp. JS666.";
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Coproporphyrinogen-III + O(2) + 2 H(+) =
CC       protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
CC   -!- PATHWAY: Porphyrin metabolism; protoporphyrin-IX biosynthesis;
CC       protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step
CC       1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the aerobic coproporphyrinogen-III oxidase
CC       family.
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DR   EMBL; CP000316; ABE43900.1; -; Genomic_DNA.
DR   RefSeq; YP_548798.1; -.
DR   GeneID; 4015376; -.
DR   GenomeReviews; CP000316_GR; Bpro_1970.
DR   KEGG; pol:Bpro_1970; -.
DR   NMPDR; fig|296591.1.peg.2636; -.
DR   HOGENOM; Q12C42; -.
DR   OMA; Q12C42; VKAYLLD.
DR   BioCyc; PSP296591:BPRO_1970-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004109; F:coproporphyrinogen oxidase activity; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006779; P:porphyrin biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00333; -; 1.
DR   InterPro; IPR001260; Coprogen_oxidas.
DR   InterPro; IPR018375; Coproporphyrinogen-3_ox_CS.
DR   Gene3D; G3DSA:3.40.1500.10; Coprogen_oxidas; 1.
DR   PANTHER; PTHR10755; Coprogen_oxidas; 1.
DR   Pfam; PF01218; Coprogen_oxidas; 1.
DR   PIRSF; PIRSF000166; Coproporphyri_ox; 1.
DR   PRINTS; PR00073; COPRGNOXDASE.
DR   PROSITE; PS01021; COPROGEN_OXIDASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Oxidoreductase; Porphyrin biosynthesis.
FT   CHAIN         1    308       Coproporphyrinogen-III oxidase, aerobic.
FT                                /FTId=PRO_1000019475.
SQ   SEQUENCE   308 AA;  34848 MW;  F3E91D4F08C07A34 CRC64;
     MSMTELSGVR TFLLGLQERV TAAVAEVDGG DFITDAWQKE PGEPLQGNGI TKILENGEVF
     ERAGCGFSHV QGSRLPPSAT QHRPELAGAP FEAMGVSLVF HPRNPYVPTV HMNVRMLAAT
     PVSAGPAEAV CWFGGGMDLT PYYGFDEDAV HFHQTCKDAL APFGGDKYPR FKQWCDEYFY
     LKHRQEQRGI GGIFFDDFQE LGLEQSFAMM QSVADSFLPA YLPIVRRRQS QPYGARERDF
     QLYRRGRYVE FNLVWDRGTH FGLQSGGRTE SILMSMPPLA SWSYQHRAEA GSPEERLYKE
     FLIRRDWV
//