ID   Q12AQ9_POLSJ            Unreviewed;       576 AA.
AC   Q12AQ9;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:ABE44383.1};
GN   OrderedLocusNames=Bpro_2464 {ECO:0000313|EMBL:ABE44383.1};
OS   Polaromonas sp. (strain JS666 / ATCC BAA-500).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Polaromonas.
OX   NCBI_TaxID=296591 {ECO:0000313|EMBL:ABE44383.1, ECO:0000313|Proteomes:UP000001983};
RN   [1] {ECO:0000313|Proteomes:UP000001983}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JS666 / ATCC BAA-500 {ECO:0000313|Proteomes:UP000001983};
RX   PubMed=18723656; DOI=10.1128/AEM.00197-08;
RA   Mattes T.E., Alexander A.K., Richardson P.M., Munk A.C., Han C.S.,
RA   Stothard P., Coleman N.V.;
RT   "The genome of Polaromonas sp. strain JS666: insights into the evolution of
RT   a hydrocarbon- and xenobiotic-degrading bacterium, and features of
RT   relevance to biotechnology.";
RL   Appl. Environ. Microbiol. 74:6405-6416(2008).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000316; ABE44383.1; -; Genomic_DNA.
DR   RefSeq; WP_011483381.1; NC_007948.1.
DR   AlphaFoldDB; Q12AQ9; -.
DR   STRING; 296591.Bpro_2464; -.
DR   KEGG; pol:Bpro_2464; -.
DR   eggNOG; COG0840; Bacteria.
DR   eggNOG; COG5278; Bacteria.
DR   HOGENOM; CLU_000445_107_27_4; -.
DR   OrthoDB; 9763018at2; -.
DR   Proteomes; UP000001983; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 2.
DR   CDD; cd19410; HK9-like_sensor; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR007891; CHASE3.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF05227; CHASE3; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 2.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001983};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        185..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          206..260
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          261..299
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          304..540
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          351..378
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          150..185
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        351..376
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   576 AA;  61233 MW;  88D2AA95007670BA CRC64;
     MKWNVGTKMG AGFGLAMVFF VIVGAVSYRS TTQLIEASDL RQHTYEVLSR LAEMELLSAD
     MQNGLRGYVI TGEEKYLEPY QTAVGKIDKI LQEARKLTED NLREQRRLDA LEPLVKSRID
     LARETIDAIR TKGEAAGVEL IKTGKGRTLT SEIRKVIDEM EREEKDLLKQ RAEAAQNDAD
     NAKQIIVLGT LAALVFAALA GFVITRNIAR PLQDLTAVAE RITLGDLSVN VPVDDTRSDE
     VGALARTFDR MVQSLRAMAS AAEQIAAGDL RSTIKPQSPD DVLGTAFARM SESLREQIRG
     LAEGANVLGS AASEIVASTT QLAASASQSA AAVSETTTTV EEVRQTAQVA SQKAKQVSDS
     AQKAAQSSQS GRKSTEDVAA GMNRIRLQME AIAASMARLS EQSQAIGRIM ATVEDLAAQS
     NLLAVNAAIE AARAGEHGKG FGVVAQEVKS LAEQSRQATN QVRTILGDIQ KATIAAVLAT
     EQGNKAVEAG SRQSEVAGAS IQALAGSVTE AAQAATQIAA SSQQQLVGVD QVAGAMESIR
     QASTQNVAGA RQLEVAARNL DELGQRLKQM VALYTV
//