ID   Q12AQ8_POLSJ            Unreviewed;       555 AA.
AC   Q12AQ8;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:ABE44384.1};
GN   OrderedLocusNames=Bpro_2465 {ECO:0000313|EMBL:ABE44384.1};
OS   Polaromonas sp. (strain JS666 / ATCC BAA-500).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Polaromonas.
OX   NCBI_TaxID=296591 {ECO:0000313|EMBL:ABE44384.1, ECO:0000313|Proteomes:UP000001983};
RN   [1] {ECO:0000313|Proteomes:UP000001983}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JS666 / ATCC BAA-500 {ECO:0000313|Proteomes:UP000001983};
RX   PubMed=18723656; DOI=10.1128/AEM.00197-08;
RA   Mattes T.E., Alexander A.K., Richardson P.M., Munk A.C., Han C.S.,
RA   Stothard P., Coleman N.V.;
RT   "The genome of Polaromonas sp. strain JS666: insights into the evolution of
RT   a hydrocarbon- and xenobiotic-degrading bacterium, and features of
RT   relevance to biotechnology.";
RL   Appl. Environ. Microbiol. 74:6405-6416(2008).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000316; ABE44384.1; -; Genomic_DNA.
DR   RefSeq; WP_011483382.1; NC_007948.1.
DR   AlphaFoldDB; Q12AQ8; -.
DR   STRING; 296591.Bpro_2465; -.
DR   KEGG; pol:Bpro_2465; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_4; -.
DR   OrthoDB; 9763018at2; -.
DR   Proteomes; UP000001983; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001983};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        173..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          195..247
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          283..519
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          330..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        330..355
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   555 AA;  58971 MW;  F8909378A89B380B CRC64;
     MKISTRLSLA GIFSVGVVAV IGFVLLSATH QVRQELTKNE TAGEILNAAT AVRYLTLEYV
     ASHEDRVRAQ WELRHASLSK LLAGATEFTG QEEQSIIEDL RHTHQGVNTL FTELAANQQN
     REAEKGKGAI LKDLESRLTG QIMNKAQAMI SGALSLSDRS RTGVLDAQQR TSAAVVTFGG
     VVVFVIAATL FLALGSVTRP LEKLREGIAI VGAGNLDHRL AITAKDEIGS LSRAFDEMTE
     KLKATTVSRD ELGQGNAVLQ AEVAERKRVE ENLRLLMQET QEIVNVLSSF SSEIVASTTQ
     LAASASQSAA AVTETTTTVE EVRQTAQVAS QKARLVSDSA QKAAQSSQNG RKSTEDVGAG
     MTRIRQQMEA IAASMTRLSE QSRAIGRIMA SVEDLAAQSN LLAVNAAIEA ARAGEHGKGF
     GVVAQEVKSL AEQSRQATTQ VRTILGDIQK ATIAAVLATE QGSKAVEAGS RQTEVAGESI
     QALAGSVTEA VQAATQIAAS SQQQLAGVDQ VAGAMESIRQ ASTQNVASAR QLEVAARNLD
     ELGQRLKQMA ERYKV
//