Q129M7 (GLMM_POLSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Bpro_2850

Organism

Polaromonas sp. (strain JS666 / ATCC BAA-500) [Complete proteome] [HAMAP]

Taxonomic identifier

296591 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Polaromonas

Protein attributes

Sequence length	443 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 443	443	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000301354
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q129M7 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: 52ECE925D412CAD4	FASTA	443	47,470
	10 20 30 40 50 60 MTRKYFGTDG IRGTVGQPPI TPDFVLRLAH AVGRVLRRVE SRPTVLIGKD TRISGYMLES 70 80 90 100 110 120 ALESGFNSAG VDVVLLGPLP TPGVAYLTRA QRASLGVVIS ASHNAYPDNG IKFFSAQGTK 130 140 150 160 170 180 LSDEWELAVE AALEEPPVWV DSATLGKARR LDDAAGRYIE FCKSTFAHDL TLKGLKIVVD 190 200 210 220 230 240 GAHGAAYHIA PKVFHELGAE VIAIGCAPDG LNINHEVGAT HPEALITAVK ANQADYGIAL 250 260 270 280 290 300 DGDADRLQMV DADGRLFNGD EVLFLMVSER LARGEKVPGT VGTLMTNMAV ELALKSRGVE 310 320 330 340 350 360 FVRAKVGDRY VLEELEKRGW LLGGEGSGHL LALDKHTTGD GLISALQVLQ ACVRSGKTIA 370 380 390 400 410 420 QLLGDVVLFP QTLVNVRLKP GQDWKASEKL ALETKAVEAE LGDTGRLLIR ASGTEPLLRV 430 440 MVEARDARQA KACAERVADT VRS

References

[1]

"Complete sequence of chromosome of Polaromonas sp. JS666." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Richardson P. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JS666 / ATCC BAA-500.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000316 Genomic DNA. Translation: ABE44765.1.
RefSeq	YP_549663.1. NC_007948.1.
3D structure databases
ProteinModelPortal	Q129M7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q129M7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4014500.
GenomeReviews	Gene locus Bpro_2850 in contig CP000316_GR.
KEGG	pol:Bpro_2850.
NMPDR	fig|296591.1.peg.5441.
PATRIC	22958868. VBIPolSp102244_2894.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	PLEDIQV.
PhylomeDB	Q129M7.
ProtClustDB	PRK10887.
Enzyme and pathway databases
BioCyc	PSP296591:BPRO_2850-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_POLSJ

Accession

Primary (citable) accession number: Q129M7

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	August 22, 2006
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program