ID   Q129G6_POLSJ            Unreviewed;       430 AA.
AC   Q129G6;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   27-MAR-2024, entry version 91.
DE   SubName: Full=4-aminobutyrate aminotransferase apoenzyme {ECO:0000313|EMBL:ABE44826.1};
DE            EC=2.6.1.19 {ECO:0000313|EMBL:ABE44826.1};
GN   OrderedLocusNames=Bpro_2912 {ECO:0000313|EMBL:ABE44826.1};
OS   Polaromonas sp. (strain JS666 / ATCC BAA-500).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Polaromonas.
OX   NCBI_TaxID=296591 {ECO:0000313|EMBL:ABE44826.1, ECO:0000313|Proteomes:UP000001983};
RN   [1] {ECO:0000313|Proteomes:UP000001983}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JS666 / ATCC BAA-500 {ECO:0000313|Proteomes:UP000001983};
RX   PubMed=18723656; DOI=10.1128/AEM.00197-08;
RA   Mattes T.E., Alexander A.K., Richardson P.M., Munk A.C., Han C.S.,
RA   Stothard P., Coleman N.V.;
RT   "The genome of Polaromonas sp. strain JS666: insights into the evolution of
RT   a hydrocarbon- and xenobiotic-degrading bacterium, and features of
RT   relevance to biotechnology.";
RL   Appl. Environ. Microbiol. 74:6405-6416(2008).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|ARBA:ARBA00008954,
CC       ECO:0000256|RuleBase:RU003560}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000316; ABE44826.1; -; Genomic_DNA.
DR   RefSeq; WP_011483824.1; NC_007948.1.
DR   AlphaFoldDB; Q129G6; -.
DR   STRING; 296591.Bpro_2912; -.
DR   KEGG; pol:Bpro_2912; -.
DR   eggNOG; COG0160; Bacteria.
DR   HOGENOM; CLU_016922_10_0_4; -.
DR   OrthoDB; 3398487at2; -.
DR   Proteomes; UP000001983; Chromosome.
DR   GO; GO:0034386; F:4-aminobutyrate:2-oxoglutarate transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009448; P:gamma-aminobutyric acid metabolic process; IEA:InterPro.
DR   CDD; cd00610; OAT_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR004632; 4NH2But_aminotransferase_bac.
DR   InterPro; IPR005814; Aminotrans_3.
DR   InterPro; IPR049704; Aminotrans_3_PPA_site.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   NCBIfam; TIGR00700; GABAtrnsam; 1.
DR   PANTHER; PTHR11986; AMINOTRANSFERASE CLASS III; 1.
DR   PANTHER; PTHR11986:SF58; LEUCINE_METHIONINE RACEMASE; 1.
DR   Pfam; PF00202; Aminotran_3; 1.
DR   PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 2.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000256|ARBA:ARBA00022576,
KW   ECO:0000313|EMBL:ABE44826.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|RuleBase:RU003560};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001983};
KW   Transferase {ECO:0000313|EMBL:ABE44826.1}.
SQ   SEQUENCE   430 AA;  45663 MW;  ACB4D8A0D6836497 CRC64;
     MPSNQPTTNA ALMARRKAAV ARGVGQTHEI FVSRARNAEF WDVEDRRYID FAGGIAVLNT
     GHLHPQVIAA VKTQLDLYTH TCFQVVAYEP YVELSEKLNA LAPGNFAKKT LLLSTGAEAV
     ENAVKVARAY TKRPGIIAFT GGYHGRTNMT LGMTGKVAPY KLGFGPFPGE VFHALYPNVL
     HGVSVDQALH SVELILKNDI EAERVAAFIL EPVQGEGGFY IAPPEFITGL KALADRHGIL
     LIADEVQTGA GRTGTWFASE QWPVAPDLIT TAKSMAGGFP ISGLVGRADV MDAPAPGGLG
     GTYAGSPIGC AAALAVLKVF EDEKLLERSK ALGAHLLKGL RAIAEKEVTI GDVRGLGAMV
     AMELFENGDV ARPNAALTQR VVAEAARRGL ILLSCGTYGN VIRILVPLTA NDALLDEGLK
     ILADSFSALR
//