Q12938 (Q12938_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: 12-lipoxygenase EMBL AAA35482.1
Organism	Homo sapiens (Human) EMBL AAA35482.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	79 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Molecular_function	metal ion binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	79	1	EMBL AAA35482.1

Sequences

	Sequence		Length	Mass (Da)
	Q12938 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 6E00393D2712B3D6	FASTA	79	9,448
	10 20 30 40 50 60 KRHLLQDDAW FCNWISVQGP GANGDEFRFP CYRWVEGDRI LSLPEGTART VVDDPQGLFK 70 KHREEELAER RKLYRWGNW

References

[1]	"Evidence that a porcine leukocyte type of 12-lipoxygenase is expressed and regulation in human adrenal glomerulosa cells." Nadler J., Rossi J.J., Yamamoto S., Yoshimoto T., Ben-Ezra J., Valente G., Natarajan R., Gu J.-l. Submitted (JUN-1992) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Adrenal zona glomerulosa EMBL AAA35482.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M95923 mRNA. Translation: AAA35482.1.
IPI	IPI00719802.
UniGene	Hs.73809.
3D structure databases
HSSP	HSSP built from PDB template 1LOX based on UniProtKB P12530.
ProteinModelPortal	Q12938.
ModBase	Search...
Proteomic databases
PRIDE	Q12938.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.60.60.20. 1 hit.
InterPro	IPR008976. Lipase_LipOase. IPR000907. LipOase. IPR013819. LipOase_C. IPR001024. LipOase_LH2. [Graphical view]
PANTHER	PTHR11771. PTHR11771. 1 hit.
Pfam	PF01477. PLAT. 1 hit. [Graphical view]
SUPFAM	SSF49723. Lipase_LipOase. 1 hit.
PROSITE	PS51393. LIPOXYGENASE_3. 1 hit. PS50095. PLAT. 1 hit. [Graphical view]
ProtoNet	Search...
Other
BindingDB	Q12938.

Entry information

Entry name

Q12938_HUMAN

Accession

Primary (citable) accession number: Q12938

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	March 6, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.