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1 to 25 of 53  Show
  1. 1
    "Identification of a mutation in the ileal sodium-dependent bile acid transporter gene that abolishes transport activity."
    Wong M.H., Oelkers P., Dawson P.A.
    J. Biol. Chem. 270:27228-27234(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANTS ALA-171 AND CD SER-290.
    Category: Sequences.
    Tissue: Ileum.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2)."
    Oelkers P., Kirby L.C., Heubi J.E., Dawson P.A.
    J. Clin. Invest. 99:1880-1887(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS PBAM PRO-243 AND MET-262, VARIANT ALA-171.
    Category: Pathology & Biotech, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5 and mapped to 11 other entries.

  4. 4
    "The DNA sequence and analysis of human chromosome 13."
    Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.
    Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT ALA-171.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 806 other entries.

  5. 5
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  6. 6
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ALA-171.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50494 other entries.

  7. 7
    "Human ileal sodium-dependent bile acid transporter gene (promoter, exon 1 and intron 1)."
    Stengelin S., Becker W., Maier M., Rosenberger J., Kramer W.
    Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-22.
    Category: Sequences.
    Tissue: Blood.
    Source: UniProtKB/Swiss-Prot (reviewed).
  8. 8
    "Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2)."
    Zhang E.Y., Phelps M.A., Banerjee A., Khantwal C.M., Chang C., Helsper F., Swaan P.W.
    Biochemistry 43:11380-11392(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: GLYCOSYLATION AT ASN-10, MUTAGENESIS OF ASN-10 AND ASN-328, TOPOLOGY.
    Category: Subcellular Location, Pathology & Biotech, PTM / Processing.
    Source: UniProtKB/Swiss-Prot (reviewed).
  9. 9
    "Analysis of the ileal bile acid transporter gene, SLC10A2, in subjects with familial hypertriglyceridemia."
    Love M.W., Craddock A.L., Angelin B., Brunzell J.D., Duane W.C., Dawson P.A.
    Arterioscler. Thromb. Vasc. Biol. 21:2039-2045(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS ILE-98; ILE-159 AND ALA-171.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  10. 10
    "Absence of dysfunctional ileal sodium-bile acid cotransporter gene mutations in patients with adult-onset idiopathic bile acid malabsorption."
    Montagnani M., Love M.W., Rossel P., Dawson P.A., Qvist P.
    Scand. J. Gastroenterol. 36:1077-1080(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS ILE-98 AND ALA-171.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  11. 11
    "An association between genetic polymorphisms in the ileal sodium-dependent bile acid transporter gene and the risk of colorectal adenomas."
    Wang W., Xue S., Ingles S.A., Chen Q., Diep A.T., Frankl H.D., Stolz A., Haile R.W.
    Cancer Epidemiol. Biomarkers Prev. 10:931-936(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Associated with CANCER: colorectal cancer.Imported, Associated with CANCER: colorectal adenomas.Imported, Observational study of gene-disease association. (HuGE Navigator)Imported.
    Source: GAD:134480, GeneRIF:6555, GAD:134481.
  12. 12
    "Human apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated by the peroxisome proliferator-activated receptor alpha."
    Jung D., Fried M., Kullak-Ublick G.A.
    J. Biol. Chem. 277:30559-30566(2002) [PubMed] [Europe PMC] [Abstract]
    Annotation: reglation of the ASBT gene by PPARalphaImported.
    Source: GeneRIF:6555.
  13. 13
    "Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter."
    Zelcer N., Saeki T., Bot I., Kuil A., Borst P.
    Biochem. J. 369:23-30(2003) [PubMed] [Europe PMC] [Abstract]
    Annotation: role in transport of bile acids in multidrug-resistance-protein 3-overexpressing cellsImported.
    Source: GeneRIF:6555.
  14. 14
    "Bile acid-induced negative feedback regulation of the human ileal bile acid transporter."
    Neimark E., Chen F., Li X., Shneider B.L.
    Hepatology 40:149-156(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: Positively regulated by retinoic acid. Bile acids induce negative feedback regulation of human ASBT via farnesoid X-receptor-mediated short heterodimer partner-dependent effect upon retinoic acid receptor/retinoid X receptor activation of ASBT.Imported.
    Source: GeneRIF:6555.
  15. 15
    "Degradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytes."
    Xia X., Roundtree M., Merikhi A., Lu X., Shentu S., Lesage G.
    J. Biol. Chem. 279:44931-44937(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: SLC10A2 expression is regulated by the ubiquitin-proteasome pathwayImported.
    Source: GeneRIF:6555.

    This publication is mapped to 3 other entries.

  16. 16
    "Site-directed mutagenesis and use of bile acid-MTS conjugates to probe the role of cysteines in the human apical sodium-dependent bile acid transporter (SLC10A2)."
    Banerjee A., Ray A., Chang C., Swaan P.W.
    Biochemistry 44:8908-8917(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: BIle acid-methanethiosulfonyl can serve as novel and powerful tools to probe the role of endogenous as well as engineered Cys residues in the bile acid binding region(s) of hASBT.Imported.
    Source: GeneRIF:6555.
  17. 17
    "Ileal bile acid-binding protein, functionally associated with the farnesoid X receptor or the ileal bile acid transporter, regulates bile acid activity in the small intestine."
    Nakahara M., Furuya N., Takagaki K., Sugaya T., Hirota K., Fukamizu A., Kanda T., Fujii H., Sato R.
    J. Biol. Chem. 280:42283-42289(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: current data provide the first evidence that I-BABP is functionally associated with FXR and IBAT in the nucleus and on the membrane respectively stimulating FXR transcriptional activity and the conjugated bile acid uptake mediated by IBAT in the ileumImported.
    Source: GeneRIF:6555.
  18. 18
    "Apical sodium bile acid transporter and ileal lipid binding protein in gallstone carriers."
    Bergheim I., Harsch S., Mueller O., Schimmel S., Fritz P., Stange E.F.
    J. Lipid Res. 47:42-50(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: ASBT and ILBP protein were 48% and 67% lower in normal weight gallstone carriers than in controls (P < 0.05); similar differences were found for mRNA expression levels.Imported.
    Source: GeneRIF:6555.

    This publication is mapped to 2 other entries.

  19. 19
    "Membrane topology of human ASBT (SLC10A2) determined by dual label epitope insertion scanning mutagenesis. New evidence for seven transmembrane domains."
    Banerjee A., Swaan P.W.
    Biochemistry 45:943-953(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: this study determines a 7TM topology for hASBT and refutes the previously proposed 9TM modelImported.
    Source: GeneRIF:6555.
  20. 20
    "Apical sodium dependent bile acid transporter (ASBT, SLC10A2): a potential prodrug target."
    Balakrishnan A., Polli J.E.
    Mol. Pharm. 3:223-230(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: hASBT-mediated prodrug targeting is discussed including QSAR in vitro models for hASBT assay and the current progress in utilizing hASBT as a drug delivery target.Imported.
    Source: GeneRIF:6555.
  21. 21
    "Influence of charge and steric bulk in the C-24 region on the interaction of bile acids with human apical sodium-dependent bile acid transporter."
    Balakrishnan A., Wring S.A., Coop A., Polli J.E.
    Mol. Pharm. 3:282-292(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: Although the presence of a single negative charge was not essential for interaction with hASBT monoanionic conjugates are favored for hASBT-mediated transport compared to cationic and zwitterionic conjugates.Imported.
    Source: GeneRIF:6555.
  22. 22
    "Transmembrane domain VII of the human apical sodium-dependent bile acid transporter ASBT (SLC10A2) lines the substrate translocation pathway."
    Hussainzada N., Banerjee A., Swaan P.W.
    Mol. Pharmacol. 70:1565-1574(2006) [PubMed] [Europe PMC] [Abstract]
    Annotation: These data suggest that transmembrane segment 7 (TM7) plays a dominant role in the hASBT translocation process.Imported.
    Source: GeneRIF:6555.
  23. 23
    "Transactivation of the human apical sodium-dependent bile acid transporter gene by human serum."
    Duane W.C., Xiong W., Lofgren J.
    J. Steroid Biochem. Mol. Biol. 108:137-148(2008) [PubMed] [Europe PMC] [Abstract]
    Annotation: One or more constituents of human serum stimulate ASBT gene expression largely via the down-stream AP-1 response element.Imported.
    Source: GeneRIF:6555.
  24. 24
    "Association of familial colorectal cancer with variants in the E-cadherin (CDH1) and cyclin D1 (CCND1) genes."
    Grunhage F., Jungck M., Lamberti C., Berg C., Becker U., Schulte-Witte H., Plassmann D., Rahner N., Aretz S., Friedrichs N., Buettner R., Sauerbruch T., Lammert F.
    Int J Colorectal Dis 23:147-154(2008) [PubMed] [Europe PMC] [Abstract]
    Annotation: Observational study of gene-disease association. (HuGE Navigator)Imported.
    Source: GeneRIF:6555.

    This publication is mapped to 164 other entries.

  25. 25
    "Electrostatic and potential cation-pi forces may guide the interaction of extracellular loop III with Na+ and bile acids for human apical Na+-dependent bile acid transporter."
    Banerjee A., Hussainzada N., Khandelwal A., Swaan P.W.
    Biochem. J. 410:391-400(2008) [PubMed] [Europe PMC] [Abstract]
    Annotation: Extracellular loop 3 amino acids are essential for human ASBT activity as primary substrate interaction points using long-range electrostatic attractive forces.Imported.
    Source: GeneRIF:6555.
1 to 25 of 53  Show