Reviewed, UniProtKB/Swiss-Prot Q128P8 (PNCB_POLSJ)

Names and origin

Protein names

Recommended name:
    Nicotinate phosphoribosyltransferase
      Short name=NAPRTase
    EC=2.4.2.11

Gene names

Name:	pncB
Ordered Locus Names:	Bpro_3080

Organism

Polaromonas sp. (strain JS666 / ATCC BAA-500) [Complete proteome] [HAMAP]

Taxonomic identifier

296591 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Polaromonas

Protein attributes

Sequence length	395 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00570
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP MF_00570
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAPRTase family.

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis
Cellular component	Cytoplasm
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: HAMAP nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 395	395	Nicotinate phosphoribosyltransferase HAMAP MF_00570		PRO_1000129476

Sequences

	Sequence		Length	Mass (Da)
	Q128P8-1 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: 80870C7E825DB858	FASTA	395	45,099
	10 20 30 40 50 60 MIITSLLDTD LYKFTMMQVV LHQFPGAEVE YRFKCRNAGA PGIGKLAPYV NEIREEIRGL 70 80 90 100 110 120 CNLRFQDAEL AYLKAMRFIK SDFVDFLGIF KLNEKYVSVT ALPSGEIEVS IKGPWLHTIL 130 140 150 160 170 180 FEIPVLAIIN EVYFRNTQKQ PDLTEGRKRL DTKILELQAD GLRELKIADY GTRRRFGKVW 190 200 210 220 230 240 HEEVLRTLVT RLGTGMSGQL AGTSNVLFAM KLGLTPLGTM AHEYLQACQA LGPRLRDSQV 250 260 270 280 290 300 FGFESWAREY RGDLGIALSD VYGMSAFLRD FDMYFCKLFD GARHDSGDPF EWGERMLAHY 310 320 330 340 350 360 VKNRVDPRTK TLIFSDALTV PRTIELYQQF RGRCQLAFGI GTNLTNDLGY EPLQIVIKMI 370 380 390 RCNGQPVAKL SDTPSKNMCE DEKYLAYLRQ VFEIG

References

[1]

"Complete sequence of chromosome of Polaromonas sp. JS666." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Richardson P. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000316 Genomic DNA. Translation: ABE44994.1.
RefSeq	YP_549892.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q128P8.
Genome annotation databases
GeneID	4014238.
GenomeReviews	Gene locus Bpro_3080 in contig CP000316_GR.
KEGG	pol:Bpro_3080.
NMPDR	fig|296591.1.peg.2044.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q128P8.
OMA	ALTDTFG.
Enzyme and pathway databases
BioCyc	PSP296591:BPRO_3080-MON.
Family and domain databases
HAMAP	MF_00570. [Tree]
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. [Graphical view]
PANTHER	PTHR11098:SF1. NAPRTase. 1 hit.
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PNCB_POLSJ

Accession

Primary (citable) accession number: Q128P8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	August 22, 2006
Last modified:	November 3, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)