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Q128P8 (PNCB_POLSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:Bpro_3080
OrganismPolaromonas sp. (strain JS666 / ATCC BAA-500) [Complete proteome] [HAMAP]
Taxonomic identifier296591 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaePolaromonas

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 395395Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000129476

Sequences

Sequence LengthMass (Da)Tools
Q128P8 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 80870C7E825DB858

FASTA39545,099
        10         20         30         40         50         60 
MIITSLLDTD LYKFTMMQVV LHQFPGAEVE YRFKCRNAGA PGIGKLAPYV NEIREEIRGL 

        70         80         90        100        110        120 
CNLRFQDAEL AYLKAMRFIK SDFVDFLGIF KLNEKYVSVT ALPSGEIEVS IKGPWLHTIL 

       130        140        150        160        170        180 
FEIPVLAIIN EVYFRNTQKQ PDLTEGRKRL DTKILELQAD GLRELKIADY GTRRRFGKVW 

       190        200        210        220        230        240 
HEEVLRTLVT RLGTGMSGQL AGTSNVLFAM KLGLTPLGTM AHEYLQACQA LGPRLRDSQV 

       250        260        270        280        290        300 
FGFESWAREY RGDLGIALSD VYGMSAFLRD FDMYFCKLFD GARHDSGDPF EWGERMLAHY 

       310        320        330        340        350        360 
VKNRVDPRTK TLIFSDALTV PRTIELYQQF RGRCQLAFGI GTNLTNDLGY EPLQIVIKMI 

       370        380        390 
RCNGQPVAKL SDTPSKNMCE DEKYLAYLRQ VFEIG 

« Hide

References

[1]"Complete sequence of chromosome of Polaromonas sp. JS666."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Richardson P.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JS666 / ATCC BAA-500.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000316 Genomic DNA. Translation: ABE44994.1.
RefSeqYP_549892.1. NC_007948.1.

3D structure databases

ProteinModelPortalQ128P8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING296591.Bpro_3080.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE44994; ABE44994; Bpro_3080.
GeneID4014238.
KEGGpol:Bpro_3080.
PATRIC22959360. VBIPolSp102244_3135.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMASIVCKVI.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycPSP296591:GHI4-3801-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_POLSJ
AccessionPrimary (citable) accession number: Q128P8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: August 22, 2006
Last modified: June 11, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways