SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q128P8

- PNCB_POLSJ

UniProt

Q128P8 - PNCB_POLSJ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, Bpro_3080
Organism
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciPSP296591:GHI4-3801-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:Bpro_3080
OrganismiPolaromonas sp. (strain JS666 / ATCC BAA-500)
Taxonomic identifieri296591 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaePolaromonas
ProteomesiUP000001983: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 395395Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_1000129476Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi296591.Bpro_3080.

Structurei

3D structure databases

ProteinModelPortaliQ128P8.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiSIVCKVI.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q128P8-1 [UniParc]FASTAAdd to Basket

« Hide

MIITSLLDTD LYKFTMMQVV LHQFPGAEVE YRFKCRNAGA PGIGKLAPYV    50
NEIREEIRGL CNLRFQDAEL AYLKAMRFIK SDFVDFLGIF KLNEKYVSVT 100
ALPSGEIEVS IKGPWLHTIL FEIPVLAIIN EVYFRNTQKQ PDLTEGRKRL 150
DTKILELQAD GLRELKIADY GTRRRFGKVW HEEVLRTLVT RLGTGMSGQL 200
AGTSNVLFAM KLGLTPLGTM AHEYLQACQA LGPRLRDSQV FGFESWAREY 250
RGDLGIALSD VYGMSAFLRD FDMYFCKLFD GARHDSGDPF EWGERMLAHY 300
VKNRVDPRTK TLIFSDALTV PRTIELYQQF RGRCQLAFGI GTNLTNDLGY 350
EPLQIVIKMI RCNGQPVAKL SDTPSKNMCE DEKYLAYLRQ VFEIG 395
Length:395
Mass (Da):45,099
Last modified:August 22, 2006 - v1
Checksum:i80870C7E825DB858
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000316 Genomic DNA. Translation: ABE44994.1.
RefSeqiWP_011483990.1. NC_007948.1.
YP_549892.1. NC_007948.1.

Genome annotation databases

EnsemblBacteriaiABE44994; ABE44994; Bpro_3080.
GeneIDi4014238.
KEGGipol:Bpro_3080.
PATRICi22959360. VBIPolSp102244_3135.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000316 Genomic DNA. Translation: ABE44994.1 .
RefSeqi WP_011483990.1. NC_007948.1.
YP_549892.1. NC_007948.1.

3D structure databases

ProteinModelPortali Q128P8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 296591.Bpro_3080.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE44994 ; ABE44994 ; Bpro_3080 .
GeneIDi 4014238.
KEGGi pol:Bpro_3080.
PATRICi 22959360. VBIPolSp102244_3135.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi SIVCKVI.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci PSP296591:GHI4-3801-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JS666 / ATCC BAA-500.

Entry informationi

Entry nameiPNCB_POLSJ
AccessioniPrimary (citable) accession number: Q128P8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: August 22, 2006
Last modified: September 3, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi