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Q12789 (TF3C1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 118. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
General transcription factor 3C polypeptide 1
Alternative name(s):
TF3C-alpha
TFIIIC box B-binding subunit
Transcription factor IIIC 220 kDa subunit
Short name=TFIIIC 220 kDa subunit
Short name=TFIIIC220
Transcription factor IIIC subunit alpha
Gene names
Name:GTF3C1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length2109 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. Binds to the box B promoter element.

Subunit structure

Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6. Interacts with IGHMBP2. Ref.12

Subcellular location

Nucleus.

Sequence similarities

Belongs to the TFIIIC subunit 1 family.

Sequence caution

The sequence AAA17985.1 differs from that shown. Reason: Frameshift at positions 152 and 189.

The sequence AAA85638.1 differs from that shown. Reason: Contaminating sequence. Potential vector sequence at the N-terminus.

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q12789-2)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q12789-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1933-1957: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 21092109General transcription factor 3C polypeptide 1
PRO_0000209710

Regions

Compositional bias343 – 3519Asp/Glu-rich (acidic)
Compositional bias1205 – 123329Arg/Lys-rich (basic)
Compositional bias1613 – 162412Asp/Glu-rich (acidic)

Amino acid modifications

Modified residue6671Phosphoserine Ref.16
Modified residue7391Phosphoserine Ref.10 Ref.16
Modified residue10621Phosphoserine Ref.10 Ref.14 Ref.16
Modified residue10681Phosphoserine Ref.6 Ref.13 Ref.14 Ref.16
Modified residue16321Phosphoserine Ref.10 Ref.14
Modified residue16531Phosphoserine Ref.7 Ref.10 Ref.14
Modified residue18561Phosphoserine Ref.10
Modified residue18651Phosphoserine Ref.10 Ref.13 Ref.14
Modified residue18681Phosphoserine Ref.10 Ref.13 Ref.14
Modified residue18961Phosphoserine By similarity
Modified residue19691Phosphoserine Ref.8

Natural variations

Alternative sequence1933 – 195725Missing in isoform 2.
VSP_021819
Natural variant18891Q → E.
Corresponds to variant rs35233306 [ dbSNP | Ensembl ].
VAR_047534
Natural variant19591F → S.
Corresponds to variant rs12919017 [ dbSNP | Ensembl ].
VAR_047535
Natural variant20771E → K.
Corresponds to variant rs2228248 [ dbSNP | Ensembl ].
VAR_047536

Experimental info

Sequence conflict1411A → P in AAA17985. Ref.1
Sequence conflict1531A → P in AAA17985. Ref.1
Sequence conflict1561A → P in AAA17985. Ref.1
Sequence conflict1611A → P in AAA17985. Ref.1
Sequence conflict1641G → A in AAA17985. Ref.1
Sequence conflict9771L → V in AAA17985. Ref.1
Sequence conflict1015 – 10184ARSS → GRRR in AAA17985. Ref.1
Sequence conflict12561Q → H in AAA17985. Ref.1
Sequence conflict13161V → L in AAA17985. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified November 25, 2008. Version 4.
Checksum: 37A03135EFE695FC

FASTA2,109238,875
        10         20         30         40         50         60 
MDALESLLDE VALEGLDGLC LPALWSRLET RVPPFPLPLE PCTQEFLWRA LATHPGISFY 

        70         80         90        100        110        120 
EEPRERPDLQ LQDRYEEIDL ETGILESRRD PVALEDVYPI HMILENKDGI QGSCRYFKER 

       130        140        150        160        170        180 
KNITNDIRTK SLQPRCTMVE AFDRWGKKLI IVASQAMRYR ALIGQEGDPD LKLPDFSYCI 

       190        200        210        220        230        240 
LERLGRSRWQ GELQRDLHTT AFKVDAGKLH YHRKILNKNG LITMQSHVIR LPTGAQQHSI 

       250        260        270        280        290        300 
LLLLNRFHVD RRSKYDILME KLSVMLSTRT NHIETLGKLR EELGLCERTF KRLYQYMLNA 

       310        320        330        340        350        360 
GLAKVVSLRL QEIHPECGPC KTKKGTDVMV RCLKLLKEFK RNDHDDDEDE EVISKTVPPV 

       370        380        390        400        410        420 
DIVFERDMLT QTYDLIERRG TKGISQAEIR VAMNVGKLEA RMLCRLLQRF KVVKGFMEDE 

       430        440        450        460        470        480 
GRQRTTKYIS CVFAEESDLS RQYQREKARS ELLTTVSLAS MQEESLLPEG EDTFLSESDS 

       490        500        510        520        530        540 
EEERSSSKRR GRGSQKDTRA SANLRPKTQP HHSTPTKGGW KVVNLHPLKK QPPSFPGAAE 

       550        560        570        580        590        600 
ERACQSLASR DSLLDTSSVS EPNVSFVSHC ADSNSGDIAV IEEVRMENPK ESSSSLKTGR 

       610        620        630        640        650        660 
HSSGQDKPHE TYRLLKRRNL IIEAVTNLRL IESLFTIQKM IMDQEKQEGV STKCCKKSIV 

       670        680        690        700        710        720 
RLVRNLSEEG LLRLYRTTVI QDGIKKKVDL VVHPSMDQND PLVRSAIEQV RFRISNSSTA 

       730        740        750        760        770        780 
NRVKTSQPPV PQGEAEEDSQ GKEGPSGSGD SQLSASSRSE SGRMKKSDNK MGITPLRNYH 

       790        800        810        820        830        840 
PIVVPGLGRS LGFLPKMPRL RVVHMFLWYL IYGHPASNTV EKPSFISERR TIKQESGRAG 

       850        860        870        880        890        900 
VRPSSSGSAW EACSEAPSKG SQDGVTWEAE VELATETVYV DDASWMRYIP PIPVHRDFGF 

       910        920        930        940        950        960 
GWALVSDILL CLPLSIFIQI VQVSYKVDNL EEFLNDPLKK HTLIRFLPRP IRQQLLYKRR 

       970        980        990       1000       1010       1020 
YIFSVVENLQ RLCYMGLLQF GPTEKFQDKD QVFIFLKKNA VIVDTTICDP HYNLARSSRP 

      1030       1040       1050       1060       1070       1080 
FERRLYVLNS MQDVENYWFD LQCVCLNTPL GVVRCPRVRK NSSTDQGSDE EGSLQKEQES 

      1090       1100       1110       1120       1130       1140 
AMDKHNLERK CAMLEYTTGS REVVDEGLIP GDGLGAAGLD SSFYGHLKRN WIWTSYIINQ 

      1150       1160       1170       1180       1190       1200 
AKKENTAAEN GLTVRLQTFL SKRPMPLSAR GNSRLNIWGE ARVGSELCAG WEEQFEVDRE 

      1210       1220       1230       1240       1250       1260 
PSLDRNRRVR GGKSQKRKRL KKDPGKKIKR KKKGEFPGEK SKRLRYHDEA DQSALQRMTR 

      1270       1280       1290       1300       1310       1320 
LRVTWSMQED GLLVLCRIAS NVLNTKVKGP FVTWQVVRDI LHATFEESLD KTSHSVGRRA 

      1330       1340       1350       1360       1370       1380 
RYIVKNPQAY LNYKVCLAEV YQDKALVGDF MNRRGDYDDP KVCANEFKEF VEKLKEKFSS 

      1390       1400       1410       1420       1430       1440 
ALRNSNLEIP DTLQELFARY RVLAIGDEKD QTRKEDELNS VDDIHFLVLQ NLIQSTLALS 

      1450       1460       1470       1480       1490       1500 
DSQMKSYQSF QTFRLYREYK DHVLVKAFME CQKRSLVNRR RVNHTLGPKK NRALPFVPMS 

      1510       1520       1530       1540       1550       1560 
YQLSQTYYRI FTWRFPSTIC TESFQFLDRM RAAGKLDQPD RFSFKDQDNN EPTNDMVAFS 

      1570       1580       1590       1600       1610       1620 
LDGPGGNCVA VLTLFSLGLI SVDVRIPEQI IVVDSSMVEN EVIKSLGKDG SLEDDEDEED 

      1630       1640       1650       1660       1670       1680 
DLDEGVGGKR RSMEVKPAQA SHTNYLLMRG YYSPGIVSTR NLNPNDSIVV NSCQMKFQLR 

      1690       1700       1710       1720       1730       1740 
CTPVPARLRP AAAPLEELTM GTSCLPDTFT KLINPQENTC SLEEFVLQLE LSGYSPEDLT 

      1750       1760       1770       1780       1790       1800 
AALEILEAII ATGCFGIDKE ELRRRFSALE KAGGGRTRTF ADCIQALLEQ HQVLEVGGNT 

      1810       1820       1830       1840       1850       1860 
ARLVAMGSAW PWLLHSVRLK DREDADIQRE DPQARPLEGS SSEDSPPEGQ APPSHSPRGT 

      1870       1880       1890       1900       1910       1920 
KRRASWASEN GETDAEGTQM TPAKRPALQD SNLAPSLGPG AEDGAEAQAP SPPPALEDTA 

      1930       1940       1950       1960       1970       1980 
AAGAAQEDQE GVGEFSSPGQ EQLSGQAQPP EGSEDPRGFT ESFGAANISQ AARERDCESV 

      1990       2000       2010       2020       2030       2040 
CFIGRPWRVV DGHLNLPVCK GMMEAMLYHI MTRPGIPESS LLRHYQGVLQ PVAVLELLQG 

      2050       2060       2070       2080       2090       2100 
LESLGCIRKR WLRKPRPVSL FSTPVVEEVE VPSSLDESPM AFYEPTLDCT LRLGRVFPHE 


VNWNKWIHL 

« Hide

Isoform 2 [UniParc].

Checksum: D1D74F05BF1C6051
Show »

FASTA2,084236,278

References

« Hide 'large scale' references
[1]"Human transcription factor IIIC box B binding subunit."
L'Etoile N.D., Fahnestock M.L., Shen Y., Aebersold R., Berk A.J.
Proc. Natl. Acad. Sci. U.S.A. 91:1652-1656(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), PROTEIN SEQUENCE OF 1103-1121.
[2]"Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q."
Loftus B.J., Kim U.-J., Sneddon V.P., Kalush F., Brandon R., Fuhrmann J., Mason T., Crosby M.L., Barnstead M., Cronin L., Mays A.D., Cao Y., Xu R.X., Kang H.-L., Mitchell S., Eichler E.E., Harris P.C., Venter J.C., Adams M.D.
Genomics 60:295-308(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The sequence and analysis of duplication-rich human chromosome 16."
Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J. expand/collapse author list , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.
Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1107-2109 (ISOFORM 2).
Tissue: Brain and Cervix.
[5]"Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC."
Lagna G., Kovelman R., Sukegawa J., Roeder R.G.
Mol. Cell. Biol. 14:3053-3064(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 71-728 (ISOFORM 1).
[6]"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1068, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[7]"A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.
Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1653, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[8]"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.
Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1969, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Embryonic kidney.
[9]"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III
J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[10]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-739; SER-1062; SER-1632; SER-1653; SER-1856; SER-1865 AND SER-1868, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[11]"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[12]"Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery."
de Planell-Saguer M., Schroeder D.G., Rodicio M.C., Cox G.A., Mourelatos Z.
Hum. Mol. Genet. 18:2115-2126(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH IGHMBP2.
[13]"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1068; SER-1865 AND SER-1868, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Leukemic T-cell.
[14]"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1062; SER-1068; SER-1632; SER-1653; SER-1865 AND SER-1868, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[15]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[16]"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-667; SER-739; SER-1062 AND SER-1068, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U02619 mRNA. Translation: AAA17985.1. Frameshift.
AC002303 Genomic DNA. Translation: AAB67637.1.
AC025275 Genomic DNA. No translation available.
AC002551 Genomic DNA. Translation: AAC05811.1.
BC044857 mRNA. Translation: AAH44857.1.
BC137229 mRNA. Translation: AAI37230.1.
U06485 mRNA. Translation: AAA85638.1. Sequence problems.
CCDSCCDS32414.1. [Q12789-2]
CCDS66988.1. [Q12789-3]
PIRB56011.
I38414.
RefSeqNP_001273171.1. NM_001286242.1. [Q12789-3]
NP_001511.2. NM_001520.3. [Q12789-2]
UniGeneHs.371718.

3D structure databases

ProteinModelPortalQ12789.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid109230. 61 interactions.
DIPDIP-38212N.
IntActQ12789. 25 interactions.
MINTMINT-1154812.
STRING9606.ENSP00000348510.

PTM databases

PhosphoSiteQ12789.

Polymorphism databases

DMDM215274233.

Proteomic databases

MaxQBQ12789.
PaxDbQ12789.
PRIDEQ12789.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000356183; ENSP00000348510; ENSG00000077235. [Q12789-2]
ENST00000561623; ENSP00000455417; ENSG00000077235. [Q12789-3]
GeneID2975.
KEGGhsa:2975.
UCSCuc002dou.3. human. [Q12789-3]
uc002dov.2. human. [Q12789-2]

Organism-specific databases

CTD2975.
GeneCardsGC16M027471.
H-InvDBHIX0012915.
HGNCHGNC:4664. GTF3C1.
HPAHPA051617.
MIM603246. gene.
neXtProtNX_Q12789.
PharmGKBPA29052.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG322015.
HOGENOMHOG000154556.
HOVERGENHBG057283.
KOK15199.
OMAEFLWRAL.
OrthoDBEOG75J0MB.
PhylomeDBQ12789.
TreeFamTF351624.

Enzyme and pathway databases

ReactomeREACT_1788. Transcription.
REACT_71. Gene Expression.

Gene expression databases

ArrayExpressQ12789.
BgeeQ12789.
CleanExHS_GTF3C1.
GenevestigatorQ12789.

Family and domain databases

InterProIPR007309. TFIIIC_Bblock-bd.
[Graphical view]
PfamPF04182. B-block_TFIIIC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSGTF3C1. human.
GeneWikiGTF3C1.
GenomeRNAi2975.
NextBio11798.
PROQ12789.
SOURCESearch...

Entry information

Entry nameTF3C1_HUMAN
AccessionPrimary (citable) accession number: Q12789
Secondary accession number(s): B2RP21 expand/collapse secondary AC list , Q12838, Q6DKN9, Q9Y4W9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: November 25, 2008
Last modified: July 9, 2014
This is version 118 of the entry and version 4 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 16

Human chromosome 16: entries, gene names and cross-references to MIM