Q12769 (NU160_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nuclear pore complex protein Nup160

Alternative name(s):
160 kDa nucleoporin
Nucleoporin Nup160

Gene names

Name:	NUP160
Synonyms:	KIAA0197, NUP120

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1436 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Involved in poly(A)+ RNA transport. Ref.6
Subunit structure	Forms part of the Nup160 subcomplex in the nuclear pore which is composed of NUP160, NUP133, NUP107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and NUP153 to the nucleus. Ref.5 Ref.6
Subcellular location	Nucleus › nuclear pore complex Ref.5 Ref.6.
Caution	It is uncertain whether Met-1 or Met-35 is the initiator.
Sequence caution	The sequence AAH09822.1 differs from that shown. Reason: Erroneous initiation. The sequence BAA12110.1 differs from that shown. Reason: Probable cloning artifact. Aberrant splice sites. The sequence BAB15406.1 differs from that shown. Reason: Erroneous initiation. The sequence BAG65161.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport mRNA transport
Cellular component	Nuclear pore complex Nucleus
Coding sequence diversity	Alternative splicing Polymorphism
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Traceable author statement. Source: Reactome cytokine-mediated signaling pathway Traceable author statement. Source: Reactome glucose transport Traceable author statement. Source: Reactome mRNA export from nucleus Inferred from direct assay Ref.6. Source: UniProtKB mitotic prometaphase Traceable author statement. Source: Reactome protein transport Inferred from electronic annotation. Source: UniProtKB-KW regulation of glucose transport Traceable author statement. Source: Reactome small molecule metabolic process Traceable author statement. Source: Reactome transmembrane transport Traceable author statement. Source: Reactome viral reproduction Traceable author statement. Source: Reactome
Cellular_component	cytosol Traceable author statement. Source: Reactome nuclear pore outer ring Inferred from direct assay PubMed 17360435. Source: UniProtKB
Molecular_function	nucleocytoplasmic transporter activity Inferred from direct assay Ref.6. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q12769-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q12769-2)

The sequence of this isoform differs from the canonical sequence as follows:
     175-224: SELVVDSQMQ...TASTAWLSSD → SVSWLSAISF...QAYFDSYRLK
     225-1436: Missing.

Isoform 3 (identifier: Q12769-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-250: Missing.
     367-367: Q → QRRGFAMLPGLKLLSSSSPPTSASQCAGITSVNHSTQPEFF
     694-695: AQ → GK
     696-1436: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1436	1436	Nuclear pore complex protein Nup160		PRO_0000204851
Amino acid modifications
	Modified residue	1157	1	Phosphoserine Ref.7 Ref.8 Ref.9 Ref.10 Ref.11 Ref.13
	Modified residue	1195	1	Phosphothreonine By similarity
Natural variations
	Alternative sequence	1 – 250	250	Missing in isoform 3.		VSP_037350
	Alternative sequence	175 – 224	50	SELVV…WLSSD → SVSWLSAISFISQITLGVTN VVLERCLLELKEIWILVIPH QAYFDSYRLK in isoform 2.		VSP_007093
	Alternative sequence	225 – 1436	1212	Missing in isoform 2.		VSP_007094
	Alternative sequence	367	1	Q → QRRGFAMLPGLKLLSSSSPP TSASQCAGITSVNHSTQPEF F in isoform 3.		VSP_037351
	Alternative sequence	694 – 695	2	AQ → GK in isoform 3.		VSP_037352
	Alternative sequence	696 – 1436	741	Missing in isoform 3.		VSP_037353
	Natural variant	40	1	A → T. Ref.1 Corresponds to variant rs2305984 [ dbSNP | Ensembl ].		VAR_055409
	Natural variant	351	1	T → A. Ref.3 Corresponds to variant rs3816605 [ dbSNP | Ensembl ].		VAR_055410
Experimental info
	Sequence conflict	152	1	I → K in BAG65161. Ref.1
	Sequence conflict	991	1	G → S in BAA12110. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 26, 2009. Version 3. Checksum: 274C063A3CE69F48	FASTA	1,436	162,121
	10 20 30 40 50 60 MLHLSAAPPA PPPEVTATAR PCLCSVGRRG DGGKMAAAGA LERSFVELSG AERERPRHFR 70 80 90 100 110 120 EFTVCSIGTA NAVAGAVKYS ESAGGFYYVE SGKLFSVTRN RFIHWKTSGD TLELMEESLD 130 140 150 160 170 180 INLLNNAIRL KFQNCSVLPG GVYVSETQNR VIILMLTNQT VHRLLLPHPS RMYRSELVVD 190 200 210 220 230 240 SQMQSIFTDI GKVDFTDPCN YQLIPAVPGI SPNSTASTAW LSSDGEALFA LPCASGGIFV 250 260 270 280 290 300 LKLPPYDIPG MVSVVELKQS SVMQRLLTGW MPTAIRGDQS PSDRPLSLAV HCVEHDAFIF 310 320 330 340 350 360 ALCQDHKLRM WSYKEQMCLM VADMLEYVPV KKDLRLTAGT GHKLRLAYSP TMGLYLGIYM 370 380 390 400 410 420 HAPKRGQFCI FQLVSTESNR YSLDHISSLF TSQETLIDFA LTSTDIWALW HDAENQTVVK 430 440 450 460 470 480 YINFEHNVAG QWNPVFMQPL PEEEIVIRDD QDPREMYLQS LFTPGQFTNE ALCKALQIFC 490 500 510 520 530 540 RGTERNLDLS WSELKKEVTL AVENELQGSV TEYEFSQEEF RNLQQEFWCK FYACCLQYQE 550 560 570 580 590 600 ALSHPLALHL NPHTNMVCLL KKGYLSFLIP SSLVDHLYLL PYENLLTEDE TTISDDVDIA 610 620 630 640 650 660 RDVICLIKCL RLIEESVTVD MSVIMEMSCY NLQSPEKAAE QILEDMITID VENVMEDICS 670 680 690 700 710 720 KLQEIRNPIH AIGLLIREMD YETEVEMEKG FNPAQPLNIR MNLTQLYGSN TAGYIVCRGV 730 740 750 760 770 780 HKIASTRFLI CRDLLILQQL LMRLGDAVIW GTGQLFQAQQ DLLHRTAPLL LSYYLIKWGS 790 800 810 820 830 840 ECLATDVPLD TLESNLQHLS VLELTDSGAL MANRFVSSPQ TIVELFFQEV ARKHIISHLF 850 860 870 880 890 900 SQPKAPLSQT GLNWPEMITA ITSYLLQLLW PSNPGCLFLE CLMGNCQYVQ LQDYIQLLHP 910 920 930 940 950 960 WCQVNVGSCR FMLGRCYLVT GEGQKALECF CQAASEVGKE EFLDRLIRSE DGEIVSTPRL 970 980 990 1000 1010 1020 QYYDKVLRLL DVIGLPELVI QLATSAITEA GDDWKSQATL RTCIFKHHLD LGHNSQAYEA 1030 1040 1050 1060 1070 1080 LTQIPDSSRQ LDCLRQLVVV LCERSQLQDL VEFPYVNLHN EVVGIIESRA RAVDLMTHNY 1090 1100 1110 1120 1130 1140 YELLYAFHIY RHNYRKAGTV MFEYGMRLGR EVRTLRGLEK QGNCYLAALN CLRLIRPEYA 1150 1160 1170 1180 1190 1200 WIVQPVSGAV YDRPGASPKR NHDGECTAAP TNRQIEILEL EDLEKECSLA RIRLTLAQHD 1210 1220 1230 1240 1250 1260 PSAVAVAGSS SAEEMVTLLV QAGLFDTAIS LCQTFKLPLT PVFEGLAFKC IKLQFGGEAA 1270 1280 1290 1300 1310 1320 QAEAWAWLAA NQLSSVITTK ESSATDEAWR LLSTYLERYK VQNNLYHHCV INKLLSHGVP 1330 1340 1350 1360 1370 1380 LPNWLINSYK KVDAAELLRL YLNYDLLEEA VDLVSEYVDA VLGKGHQYFG IEFPLSATAP 1390 1400 1410 1420 1430 MVWLPYSSID QLLQALGENS ANSHNIALSQ KILDKLEDYQ QKVDKATRDL LYRRTL
	Isoform 2 [UniParc]. Checksum: C98755EBCB0E1BC7	FASTA	224	24,898
	10 20 30 40 50 60 MLHLSAAPPA PPPEVTATAR PCLCSVGRRG DGGKMAAAGA LERSFVELSG AERERPRHFR 70 80 90 100 110 120 EFTVCSIGTA NAVAGAVKYS ESAGGFYYVE SGKLFSVTRN RFIHWKTSGD TLELMEESLD 130 140 150 160 170 180 INLLNNAIRL KFQNCSVLPG GVYVSETQNR VIILMLTNQT VHRLLLPHPS RMYRSVSWLS 190 200 210 220 AISFISQITL GVTNVVLERC LLELKEIWIL VIPHQAYFDS YRLK
	Isoform 3 [UniParc]. Checksum: 4650AE42B030DFBC	FASTA	485	55,554
	10 20 30 40 50 60 MVSVVELKQS SVMQRLLTGW MPTAIRGDQS PSDRPLSLAV HCVEHDAFIF ALCQDHKLRM 70 80 90 100 110 120 WSYKEQMCLM VADMLEYVPV KKDLRLTAGT GHKLRLAYSP TMGLYLGIYM HAPKRGQRRG 130 140 150 160 170 180 FAMLPGLKLL SSSSPPTSAS QCAGITSVNH STQPEFFFCI FQLVSTESNR YSLDHISSLF 190 200 210 220 230 240 TSQETLIDFA LTSTDIWALW HDAENQTVVK YINFEHNVAG QWNPVFMQPL PEEEIVIRDD 250 260 270 280 290 300 QDPREMYLQS LFTPGQFTNE ALCKALQIFC RGTERNLDLS WSELKKEVTL AVENELQGSV 310 320 330 340 350 360 TEYEFSQEEF RNLQQEFWCK FYACCLQYQE ALSHPLALHL NPHTNMVCLL KKGYLSFLIP 370 380 390 400 410 420 SSLVDHLYLL PYENLLTEDE TTISDDVDIA RDVICLIKCL RLIEESVTVD MSVIMEMSCY 430 440 450 460 470 480 NLQSPEKAAE QILEDMITID VENVMEDICS KLQEIRNPIH AIGLLIREMD YETEVEMEKG FNPGK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 31-1436 (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 32-1436 (ISOFORM 2), VARIANT THR-40. Tissue: Small intestine, Testis and Trachea.
[2]	"Human chromosome 11 DNA sequence and analysis including novel gene identification." Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y. Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT ALA-351. Tissue: Muscle and Skin.
[4]	"Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1." Nagase T., Seki N., Ishikawa K., Tanaka A., Nomura N. DNA Res. 3:17-24(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 37-1436 (ISOFORM 1). Tissue: Bone marrow.
[5]	"An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells." Belgareh N., Rabut G., Bai S.W., van Overbeek M., Beaudouin J., Daigle N., Zatsepina O.V., Pasteau F., Labas V., Fromont-Racine M., Ellenberg J., Doye V. J. Cell Biol. 154:1147-1160(2001) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION, SUBUNIT, SUBCELLULAR LOCATION.
[6]	"Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export." Vasu S., Shah S., Orjalo A., Park M., Fischer W.H., Forbes D.J. J. Cell Biol. 155:339-354(2001) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION, FUNCTION, SUBUNIT, SUBCELLULAR LOCATION.
[7]	"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1157, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[8]	"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M. Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1157, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[9]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1157, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[10]	"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K. Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1157, MASS SPECTROMETRY. Tissue: Leukemic T-cell.
[11]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1157, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[12]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[13]	"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B. Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1157, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK026236 mRNA. Translation: BAB15406.1. Different initiation. AK302396 mRNA. Translation: BAG63710.1. AK304308 mRNA. Translation: BAG65161.1. Different initiation. AC021443 Genomic DNA. No translation available. AC023232 Genomic DNA. No translation available. BC008700 mRNA. Translation: AAH08700.1. BC009822 mRNA. Translation: AAH09822.1. Different initiation. BC125227 mRNA. Translation: AAI25228.1. BC125228 mRNA. Translation: AAI25229.1. D83781 mRNA. Translation: BAA12110.1. Sequence problems.
IPI	IPI00221235. IPI00748807. IPI00909318.
PIR	G02870.
RefSeq	NP_056046.1. NM_015231.1.
UniGene	Hs.731939.
3D structure databases
ProteinModelPortal	Q12769.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q12769. 9 interactions.
MINT	MINT-4301556.
STRING	9606.ENSP00000367721.
PTM databases
PhosphoSite	Q12769.
Polymorphism databases
DMDM	238054372.
Proteomic databases
PaxDb	Q12769.
PRIDE	Q12769.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000378460; ENSP00000367721; ENSG00000030066. ENST00000526870; ENSP00000431495; ENSG00000030066.
GeneID	23279.
KEGG	hsa:23279.
UCSC	uc001ngm.3. human. uc001ngn.1. human.
Organism-specific databases
CTD	23279.
GeneCards	GC11M047866.
H-InvDB	HIX0009624.
HGNC	HGNC:18017. NUP160.
MIM	607614. gene.
neXtProt	NX_Q12769.
PharmGKB	PA31850.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG254492.
HOVERGEN	HBG052681.
KO	K14303.
OMA	KCIKLQF.
OrthoDB	EOG43TZTN.
Enzyme and pathway databases
Reactome	REACT_111217. Metabolism. REACT_115566. Cell Cycle. REACT_116125. Disease. REACT_15518. Transmembrane transport of small molecules. REACT_21300. Mitotic M-M/G1 phases. REACT_6900. Immune System.
Gene expression databases
ArrayExpress	Q12769.
Bgee	Q12769.
CleanEx	HS_NUP160.
Genevestigator	Q12769.
GermOnline	ENSG00000030066. Homo sapiens.
Family and domain databases
InterPro	IPR021717. Nucleoporin_Nup160. [Graphical view]
Pfam	PF11715. Nup160. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	NUP160. human.
GenomeRNAi	23279.
NextBio	45070.
SOURCE	Search...

Entry information

Entry name

NU160_HUMAN

Accession

Primary (citable) accession number: Q12769
Secondary accession number(s): B4DYE8 , B4E2J9, Q08AD3, Q7Z5X6, Q96GB3, Q9H660

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 21, 2001
Last sequence update:	May 26, 2009
Last modified:	May 1, 2013
This is version 125 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.