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Protein
Submitted name:

Eosinophil cationic-related protein

Gene

ECRP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Eosinophil cationic-related proteinImported
Gene namesi
Name:ECRPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 159136Sequence analysisPRO_5004181011Add
BLAST

Proteomic databases

PeptideAtlasiQ12762.
PRIDEiQ12762.

Structurei

3D structure databases

ProteinModelPortaliQ12762.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 159141RNAse_PcInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the pancreatic ribonuclease family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOGENOMiHOG000276882.
HOVERGENiHBG008396.

Family and domain databases

Gene3Di3.10.130.10. 1 hit.
InterProiIPR001427. RNaseA.
IPR023412. RNaseA_domain.
[Graphical view]
PANTHERiPTHR11437. PTHR11437. 1 hit.
PfamiPF00074. RnaseA. 1 hit.
[Graphical view]
PRINTSiPR00794. RIBONUCLEASE.
ProDomiPD000535. RNaseA. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00092. RNAse_Pc. 1 hit.
[Graphical view]
SUPFAMiSSF54076. SSF54076. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q12762-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
WFQNCSLPKF VCFFCWGFWL WRAHSMSNLH SLPGLRGLTS ISRNQLQCTN
60 70 80 90 100
AMRVINNYQR RWKNRNTFLL ATFANVVNVC GNPTITCPHN RTLNNCHHSG
110 120 130 140 150
VQVPLMYCNL TTPSPQNISN CRYAQTPANM FYIVACDNRD QRRDPPQYPV

VPVHLHTII
Length:159
Mass (Da):18,453
Last modified:November 1, 1996 - v1
Checksum:i10201C2FDB94B283
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X55989 Genomic DNA. Translation: CAA39461.1.
UniGeneiHs.730362.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X55989 Genomic DNA. Translation: CAA39461.1.
UniGeneiHs.730362.

3D structure databases

ProteinModelPortaliQ12762.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ12762.
PRIDEiQ12762.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000276882.
HOVERGENiHBG008396.

Family and domain databases

Gene3Di3.10.130.10. 1 hit.
InterProiIPR001427. RNaseA.
IPR023412. RNaseA_domain.
[Graphical view]
PANTHERiPTHR11437. PTHR11437. 1 hit.
PfamiPF00074. RnaseA. 1 hit.
[Graphical view]
PRINTSiPR00794. RIBONUCLEASE.
ProDomiPD000535. RNaseA. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00092. RNAse_Pc. 1 hit.
[Graphical view]
SUPFAMiSSF54076. SSF54076. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Simonsen C.C., Kennedy J., Comstock L., Ashton N., McGrogan M.
    Submitted (OCT-1990) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: ColonImported.

Entry informationi

Entry nameiQ12762_HUMAN
AccessioniPrimary (citable) accession number: Q12762
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.