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Q12715 (Q12715_HYPJE) Unreviewed, UniProtKB/TrEMBL

Last modified January 22, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
EC=3.2.1.21 EMBL AAA18473.1
Gene names
Name:bgl1 EMBL AAA18473.1
OrganismHypocrea jecorina (Trichoderma reesei) EMBL AAA18473.1
Taxonomic identifier51453 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesHypocreaceaeTrichoderma

Protein attributes

Sequence length744 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

Ontologies

Keywords
   DomainSignal EMBL AAA18473.1
   Molecular functionGlycosidase EMBL AAA18473.1
Hydrolase
   Technical term3D-structure PDB 3ZYZ PDB 3ZZ1 PDB 4I8D
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3131 Potential EMBL AAA18473.1
Chain32 – 744713beta-D-glucoside glucohydrolase EMBL AAA18473.1
PRO_5000144180

Sites

Binding site7131Beta-D-mannose; via carbonyl oxygen
Binding site7131Mannose; via amide nitrogen

Amino acid modifications

Glycosylation2391N-linked (GlcNAc...) PDB 3ZYZ PDB 4I8D
Glycosylation3411N-linked (GlcNAc...) PDB 3ZYZ PDB 3ZZ1 PDB 4I8D

Sequences

Sequence LengthMass (Da)Tools
Q12715 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 4089433EDCEA2FC9

FASTA74478,433
        10         20         30         40         50         60 
MRYRTAAALA LATGPFARAD SHSTSGASAE AVVPPAGTPW GTAYDKAKAA LAKLNLQDKV 

        70         80         90        100        110        120 
GIVSGVGWNG GPCVGNTSPA SKISYPSLCL QDGPLGVRYS TGSTAFTPGV QAASTWDVNL 

       130        140        150        160        170        180 
IRERGQFIGE EVKASGIHVI LGPVAGPLGK TPQGGRNWEG FGVDPYLTGI AMGQTINGIQ 

       190        200        210        220        230        240 
SVGVQATAKH YILNEQELNR ETISSNPDDR TLHELYTWPF ADAVQANVAS VMCSYNKVNT 

       250        260        270        280        290        300 
TWACEDQYTL QTVLKDQLGF PGYVMTDWNA QHTTVQSANS GLDMSMPGTD FNGNNRLWGP 

       310        320        330        340        350        360 
ALTNAVNSNQ VPTSRVDDMV TRILAAWYLT GQDQAGYPSF NISRNVQGNH KTNVRAIARD 

       370        380        390        400        410        420 
GIVLLKNDAN ILPLKKPASI AVVGSAAIIG NHARNSPSCN DKGCDDGALG MGWGSGAVNY 

       430        440        450        460        470        480 
PYFVAPYDAI NTRASSQGTQ VTLSNTDNTS SGASAARGKD VAIVFITADS GEGYITVEGN 

       490        500        510        520        530        540 
AGDRNNLDPW HNGNALVQAV AGANSNVIVV VHSVGAIILE QILALPQVKA VVWAGLPSQE 

       550        560        570        580        590        600 
SGNALVDVLW GDVSPSGKLV YTIAKSPNDY NTRIVSGGSD SFSEGLFIDY KHFDDANITP 

       610        620        630        640        650        660 
RYEFGYGLSY TKFNYSRLSV LSTAKSGPAT GAVVPGGPSD LFQNVATVTV DIANSGQVTG 

       670        680        690        700        710        720 
AEVAQLYITY PSSAPRTPPK QLRGFAKLNL TPGQSGTATF NIRRRDLSYW DTASQKWVVP 

       730        740 
SGSFGISVGA SSRDIRLTST LSVA 

« Hide

References

[1]"Klonierung und Charakterisierung einiger Gene des Kohlenstoffmetabolismus von Trichoderma reesei."
Mach R.L.
Thesis (1993), Mikrobielle Biochemie, Inst. biochem. Technol
Cited for: NUCLEOTIDE SEQUENCE.
Strain: QM9414 EMBL AAA18473.1.
[2]Mach R.L.
Submitted (MAY-1994) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: QM9414 EMBL AAA18473.1.
[3]"Crystal Structure of a Glycoside Hydrolase Family 3 Beta-Glucosidase, Bgl1 from Hypocrea Jecorina at 2.1A Resolution."
Sandgren M., Kaper T., Mikkelsen N.E., Hansson H., Piens K., Gudmundsson M., Larenas E., Kelemen B., Karkehabadi S.
Submitted (AUG-2011) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 32-744, GLYCOSYLATION AT ASN-239 AND ASN-341.
[4]"Crystal Structure of Beta-D-glucoside glucohydrolase from Trichoderma reesei."
Helmich K.E., Banerjee G., Bianchetti C.M., Gudmundsson M., Sandgren M., Walton J.D., Phillips Jr. G.N.
Submitted (DEC-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.48 ANGSTROMS) OF 31-744 IN COMPLEX WITH BETA-D-MANNOSE AND MANNOSE, GLYCOSYLATION AT ASN-239 AND ASN-341.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U09580 Unassigned DNA. Translation: AAA18473.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3ZYZX-ray2.10A32-744[»]
3ZZ1X-ray2.10A32-744[»]
4I8DX-ray2.48A/B31-744[»]
ProteinModelPortalQ12715.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING51453.JGI76672.

Protein family/group databases

CAZyGH3. Glycoside Hydrolase Family 3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG1472.
OMADANITPR.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-16497.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ12715_HYPJE
AccessionPrimary (citable) accession number: Q12715
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: January 22, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)