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Q12715

- Q12715_HYPJE

UniProt

Q12715 - Q12715_HYPJE

Protein
Submitted name:

Beta-D-glucoside glucohydrolase

Gene

bgl1

Organism
Hypocrea jecorina (Trichoderma reesei)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei713 – 7131Beta-D-mannose; via carbonyl oxygen
    Binding sitei713 – 7131Mannose; via amide nitrogen

    GO - Molecular functioni

    1. beta-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    GlycosidaseImported, Hydrolase

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-16497.

    Protein family/group databases

    CAZyiGH3. Glycoside Hydrolase Family 3.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Beta-D-glucoside glucohydrolaseImported (EC:3.2.1.21Imported)
    Gene namesi
    Name:bgl1Imported
    OrganismiHypocrea jecorina (Trichoderma reesei)Imported
    Taxonomic identifieri51453 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesHypocreaceaeTrichoderma

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3131 PotentialImportedAdd
    BLAST
    Chaini32 – 744713beta-D-glucoside glucohydrolaseImportedPRO_5000144180Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi239 – 2391N-linked (GlcNAc...)Imported
    Glycosylationi341 – 3411N-linked (GlcNAc...)Imported

    Interactioni

    Protein-protein interaction databases

    STRINGi51453.JGI76672.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3ZYZX-ray2.10A32-744[»]
    3ZZ1X-ray2.10A32-744[»]
    4I8DX-ray2.48A/B31-744[»]
    ProteinModelPortaliQ12715.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    SignalImported

    Phylogenomic databases

    eggNOGiCOG1472.

    Family and domain databases

    Gene3Di3.20.20.300. 1 hit.
    3.40.50.1700. 1 hit.
    InterProiIPR026891. Fn3-like.
    IPR026892. Glyco_hydro_3.
    IPR002772. Glyco_hydro_3_C.
    IPR001764. Glyco_hydro_3_N.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PANTHERiPTHR30620. PTHR30620. 1 hit.
    PfamiPF14310. Fn3-like. 1 hit.
    PF00933. Glyco_hydro_3. 1 hit.
    PF01915. Glyco_hydro_3_C. 1 hit.
    [Graphical view]
    PRINTSiPR00133. GLHYDRLASE3.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    SSF52279. SSF52279. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q12715-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRYRTAAALA LATGPFARAD SHSTSGASAE AVVPPAGTPW GTAYDKAKAA    50
    LAKLNLQDKV GIVSGVGWNG GPCVGNTSPA SKISYPSLCL QDGPLGVRYS 100
    TGSTAFTPGV QAASTWDVNL IRERGQFIGE EVKASGIHVI LGPVAGPLGK 150
    TPQGGRNWEG FGVDPYLTGI AMGQTINGIQ SVGVQATAKH YILNEQELNR 200
    ETISSNPDDR TLHELYTWPF ADAVQANVAS VMCSYNKVNT TWACEDQYTL 250
    QTVLKDQLGF PGYVMTDWNA QHTTVQSANS GLDMSMPGTD FNGNNRLWGP 300
    ALTNAVNSNQ VPTSRVDDMV TRILAAWYLT GQDQAGYPSF NISRNVQGNH 350
    KTNVRAIARD GIVLLKNDAN ILPLKKPASI AVVGSAAIIG NHARNSPSCN 400
    DKGCDDGALG MGWGSGAVNY PYFVAPYDAI NTRASSQGTQ VTLSNTDNTS 450
    SGASAARGKD VAIVFITADS GEGYITVEGN AGDRNNLDPW HNGNALVQAV 500
    AGANSNVIVV VHSVGAIILE QILALPQVKA VVWAGLPSQE SGNALVDVLW 550
    GDVSPSGKLV YTIAKSPNDY NTRIVSGGSD SFSEGLFIDY KHFDDANITP 600
    RYEFGYGLSY TKFNYSRLSV LSTAKSGPAT GAVVPGGPSD LFQNVATVTV 650
    DIANSGQVTG AEVAQLYITY PSSAPRTPPK QLRGFAKLNL TPGQSGTATF 700
    NIRRRDLSYW DTASQKWVVP SGSFGISVGA SSRDIRLTST LSVA 744
    Length:744
    Mass (Da):78,433
    Last modified:November 1, 1996 - v1
    Checksum:i4089433EDCEA2FC9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U09580 Unassigned DNA. Translation: AAA18473.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U09580 Unassigned DNA. Translation: AAA18473.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3ZYZ X-ray 2.10 A 32-744 [» ]
    3ZZ1 X-ray 2.10 A 32-744 [» ]
    4I8D X-ray 2.48 A/B 31-744 [» ]
    ProteinModelPortali Q12715.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 51453.JGI76672.

    Protein family/group databases

    CAZyi GH3. Glycoside Hydrolase Family 3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi COG1472.

    Enzyme and pathway databases

    BioCyci MetaCyc:MONOMER-16497.

    Family and domain databases

    Gene3Di 3.20.20.300. 1 hit.
    3.40.50.1700. 1 hit.
    InterProi IPR026891. Fn3-like.
    IPR026892. Glyco_hydro_3.
    IPR002772. Glyco_hydro_3_C.
    IPR001764. Glyco_hydro_3_N.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    PANTHERi PTHR30620. PTHR30620. 1 hit.
    Pfami PF14310. Fn3-like. 1 hit.
    PF00933. Glyco_hydro_3. 1 hit.
    PF01915. Glyco_hydro_3_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00133. GLHYDRLASE3.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    SSF52279. SSF52279. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Klonierung und Charakterisierung einiger Gene des Kohlenstoffmetabolismus von Trichoderma reesei."
      Mach R.L.
      Thesis (1993), Mikrobielle Biochemie, Inst. biochem. Technol
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: QM9414Imported.
    2. Mach R.L.
      Submitted (MAY-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: QM9414Imported.
    3. "Crystal Structure of a Glycoside Hydrolase Family 3 Beta-Glucosidase, Bgl1 from Hypocrea Jecorina at 2.1A Resolution."
      Sandgren M., Kaper T., Mikkelsen N.E., Hansson H., Piens K., Gudmundsson M., Larenas E., Kelemen B., Karkehabadi S.
      Submitted (AUG-2011) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 32-744, GLYCOSYLATION AT ASN-239 AND ASN-341.
    4. "Crystal Structure of Beta-D-glucoside glucohydrolase from Trichoderma reesei."
      Helmich K.E., Banerjee G., Bianchetti C.M., Gudmundsson M., Sandgren M., Walton J.D., Phillips Jr. G.N.
      Submitted (DEC-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.48 ANGSTROMS) OF 31-744 IN COMPLEX WITH BETA-D-MANNOSE AND MANNOSE, GLYCOSYLATION AT ASN-239 AND ASN-341.

    Entry informationi

    Entry nameiQ12715_HYPJE
    AccessioniPrimary (citable) accession number: Q12715
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3