Q12715 (Q12715_HYPJE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Beta-D-glucoside glucohydrolase EMBL AAA18473.1
EC=3.2.1.21 EMBL AAA18473.1

Gene names

Name:

bgl1 EMBL AAA18473.1

Organism

Hypocrea jecorina (Trichoderma reesei) EMBL AAA18473.1

Taxonomic identifier

51453 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › sordariomyceta › Sordariomycetes › Hypocreomycetidae › Hypocreales › Hypocreaceae › Hypocrea › mitosporic Hypocrea › Trichoderma

Protein attributes

Sequence length	744 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

Ontologies

Keywords
Domain	Signal EMBL AAA18473.1
Molecular function	Glycosidase SAAS SAAS002772 EMBL AAA18473.1 Hydrolase
Technical term	3D-structure PDB 3ZYZ PDB 3ZZ1 PDB 4I8D
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	beta-glucosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 31	31	Potential EMBL AAA18473.1
	Chain	32 – 744	713	beta-D-glucoside glucohydrolase EMBL AAA18473.1		PRO_5000144180

Sequences

	Sequence		Length	Mass (Da)
	Q12715 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 4089433EDCEA2FC9	FASTA	744	78,433
	10 20 30 40 50 60 MRYRTAAALA LATGPFARAD SHSTSGASAE AVVPPAGTPW GTAYDKAKAA LAKLNLQDKV 70 80 90 100 110 120 GIVSGVGWNG GPCVGNTSPA SKISYPSLCL QDGPLGVRYS TGSTAFTPGV QAASTWDVNL 130 140 150 160 170 180 IRERGQFIGE EVKASGIHVI LGPVAGPLGK TPQGGRNWEG FGVDPYLTGI AMGQTINGIQ 190 200 210 220 230 240 SVGVQATAKH YILNEQELNR ETISSNPDDR TLHELYTWPF ADAVQANVAS VMCSYNKVNT 250 260 270 280 290 300 TWACEDQYTL QTVLKDQLGF PGYVMTDWNA QHTTVQSANS GLDMSMPGTD FNGNNRLWGP 310 320 330 340 350 360 ALTNAVNSNQ VPTSRVDDMV TRILAAWYLT GQDQAGYPSF NISRNVQGNH KTNVRAIARD 370 380 390 400 410 420 GIVLLKNDAN ILPLKKPASI AVVGSAAIIG NHARNSPSCN DKGCDDGALG MGWGSGAVNY 430 440 450 460 470 480 PYFVAPYDAI NTRASSQGTQ VTLSNTDNTS SGASAARGKD VAIVFITADS GEGYITVEGN 490 500 510 520 530 540 AGDRNNLDPW HNGNALVQAV AGANSNVIVV VHSVGAIILE QILALPQVKA VVWAGLPSQE 550 560 570 580 590 600 SGNALVDVLW GDVSPSGKLV YTIAKSPNDY NTRIVSGGSD SFSEGLFIDY KHFDDANITP 610 620 630 640 650 660 RYEFGYGLSY TKFNYSRLSV LSTAKSGPAT GAVVPGGPSD LFQNVATVTV DIANSGQVTG 670 680 690 700 710 720 AEVAQLYITY PSSAPRTPPK QLRGFAKLNL TPGQSGTATF NIRRRDLSYW DTASQKWVVP 730 740 SGSFGISVGA SSRDIRLTST LSVA

References

[1]	"Klonierung und Charakterisierung einiger Gene des Kohlenstoffmetabolismus von Trichoderma reesei." Mach R.L. Thesis (1993), Mikrobielle Biochemie, Inst. biochem. Technol Cited for: NUCLEOTIDE SEQUENCE. Strain: QM9414 EMBL AAA18473.1.
[2]	Mach R.L. Submitted (MAY-1994) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: QM9414 EMBL AAA18473.1.
[3]	"Crystal Structure of a Glycoside Hydrolase Family 3 Beta-Glucosidase, Bgl1 from Hypocrea Jecorina at 2.1A Resolution." Sandgren M., Kaper T., Mikkelsen N.E., Hansson H., Piens K., Gudmundsson M., Larenas E., Kelemen B., Karkehabadi S. Submitted (AUG-2011) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 32-744.
[4]	"Crystal Structure of Beta-D-glucoside glucohydrolase from Trichoderma reesei." Helmich K.E., Banerjee G., Bianchetti C.M., Gudmundsson M., Sandgren M., Walton J.D., Phillips Jr. G.N. Submitted (DEC-2012) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.48 ANGSTROMS) OF 31-744.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U09580 Unassigned DNA. Translation: AAA18473.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3ZYZ	X-ray	2.10	A	32-744	[»]
3ZZ1	X-ray	2.10	A	32-744	[»]
4I8D	X-ray	2.48	A/B	31-744	[»]

ProteinModelPortal

Q12715.

ModBase

Search...

Protein-protein interaction databases

STRING

51453.JGI76672.

Protein family/group databases

CAZy

GH3. Glycoside Hydrolase Family 3.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Phylogenomic databases

eggNOG

COG1472.

Enzyme and pathway databases

BioCyc

MetaCyc:MONOMER-16497.

Family and domain databases

Gene3D

3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.

InterPro

IPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]

PANTHER

PTHR30620. PTHR30620. 1 hit.

Pfam

PF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]

PRINTS

PR00133. GLHYDRLASE3.

SUPFAM

SSF52279. Glyco_hydro_3_C. 1 hit.
SSF51445. Glyco_hydro_cat. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q12715_HYPJE

Accession

Primary (citable) accession number: Q12715

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)