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Q12679

- GUNA_ASPKW

UniProt

Q12679 - GUNA_ASPKW

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Protein
Endoglucanase A
Gene
cekA, AKAW_05147
Organism
Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus awamori var. kawachi)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Has carboxylmethylcellulase activity.

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

GO - Molecular functioni

  1. cellulase activity Source: UniProtKB-EC

GO - Biological processi

  1. cellulose catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Protein family/group databases

CAZyiGH12. Glycoside Hydrolase Family 12.
mycoCLAPiEGL12A_ASPKA.

Names & Taxonomyi

Protein namesi
Recommended name:
Endoglucanase A (EC:3.2.1.4)
Alternative name(s):
CMCase-I
Carboxymethylcellulase
Cellulase A
Endo-1,4-beta-glucanase A
Gene namesi
Name:cekA
ORF Names:AKAW_05147
OrganismiAspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus awamori var. kawachi)
Taxonomic identifieri1033177 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006812: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616 Reviewed prediction
Add
BLAST
Chaini17 – 239223Endoglucanase A
PRO_0000008019Add
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

OrthoDBiEOG72VHHK.

Family and domain databases

Gene3Di2.60.120.180. 1 hit.
InterProiIPR008985. ConA-like_lec_gl_sf.
IPR013319. Glyco_hydro_11/12.
IPR002594. Glyco_hydro_12.
[Graphical view]
PfamiPF01670. Glyco_hydro_12. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q12679-1 [UniParc]FASTAAdd to Basket

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MKLSMTLSLF AATAMGQTMC SQYDSASSPP YSVNQNLWGE YQGTGSQCVY    50
VDKLSSSGAS WHTKWTWSGG EGTVKSYSNS GLTFDKKLVS DVSSIPTSVT 100
WSQDDTNVQA DVSYDLFTAA NADHATSSGD YELMIWLARY GSVQPIGKQI 150
ATATVGGKSW EVWYGTSTQA GAEQKTYSFV AGSPINSWSG DIKDFFNYLT 200
QNQGFPASSQ HLITLQFGTE PFTGGPATFT VDNWTASVN 239
Length:239
Mass (Da):25,813
Last modified:March 21, 2012 - v2
Checksum:iE3B0304A13827066
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti217 – 2171F → C in BAA02297. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D12901 mRNA. Translation: BAA02297.1.
DF126458 Genomic DNA. Translation: GAA87033.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D12901 mRNA. Translation: BAA02297.1 .
DF126458 Genomic DNA. Translation: GAA87033.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH12. Glycoside Hydrolase Family 12.
mycoCLAPi EGL12A_ASPKA.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

OrthoDBi EOG72VHHK.

Family and domain databases

Gene3Di 2.60.120.180. 1 hit.
InterProi IPR008985. ConA-like_lec_gl_sf.
IPR013319. Glyco_hydro_11/12.
IPR002594. Glyco_hydro_12.
[Graphical view ]
Pfami PF01670. Glyco_hydro_12. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and sequencing of cellulase cDNA from Aspergillus kawachii and its expression in Saccharomyces cerevisiae."
    Sakamoto S., Tamura G., Ito K., Ishikawa T., Iwano K., Nishiya N.
    Curr. Genet. 27:435-439(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: NBRC 4308.
  2. "Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used for brewing the Japanese distilled spirit shochu."
    Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., Takashita H., Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.
    Eukaryot. Cell 10:1586-1587(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NBRC 4308.

Entry informationi

Entry nameiGUNA_ASPKW
AccessioniPrimary (citable) accession number: Q12679
Secondary accession number(s): G7XJV2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: March 21, 2012
Last modified: November 13, 2013
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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