Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucoamylase

Gene

gla1

Organism
Humicola grisea
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei137SubstrateUniRule annotation1
Active sitei193Proton acceptorUniRule annotation1
Active sitei196Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationImported, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradationUniRule annotation

Protein family/group databases

CAZyiCBM20. Carbohydrate-Binding Module Family 20.
GH15. Glycoside Hydrolase Family 15.

Names & Taxonomyi

Protein namesi
Recommended name:
GlucoamylaseUniRule annotation (EC:3.2.1.3UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan glucohydrolaseUniRule annotation
Glucan 1,4-alpha-glucosidaseUniRule annotation
Gene namesi
Name:gla1Imported
OrganismiHumicola griseaImported
Taxonomic identifieri5527 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesChaetomiaceaeHumicola

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500418107320 – 620GlucoamylaseSequence analysisAdd BLAST601

Proteomic databases

PRIDEiQ12623.

Structurei

3D structure databases

ProteinModelPortaliQ12623.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini509 – 620CBM20 (carbohydrate binding type-20)InterPro annotationAdd BLAST112

Sequence similaritiesi

Belongs to the glycosyl hydrolase 15 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
2.60.40.10. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR013784. Carb-bd-like_fold.
IPR002044. CBM_fam20.
IPR000165. Glucoamylase.
IPR008291. Glucoamylase_SBD.
IPR011613. Glyco_hydro_15/PHK.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF00686. CBM_20. 1 hit.
PF00723. Glyco_hydro_15. 1 hit.
[Graphical view]
PIRSFiPIRSF001031. Glu-a-glcsd_SBD. 1 hit.
PRINTSiPR00736. GLHYDRLASE15.
SMARTiSM01065. CBM_2. 1 hit.
[Graphical view]
SUPFAMiSSF48208. SSF48208. 1 hit.
SSF49452. SSF49452. 1 hit.
PROSITEiPS51166. CBM20. 1 hit.
PS00820. GLUCOAMYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q12623-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHTFSKLLVL GSAVQSALGR PHGSSRLQER AAVDTFINTE KPIAWNKLLA
60 70 80 90 100
NIGPNGKAAP GAAAGVVIAS PSRTDPPYFF TWTPDAALVL TGIIESLGHN
110 120 130 140 150
YNTTLQQVSN PSGTFADGSG LGEAKFNVDL TAFTGEWGRP QRDGPPLRAI
160 170 180 190 200
ALIQYAKWLI ANGYKSTAKS VVWPVVKNDL AYTAQYWNET GFDLWEEVPG
210 220 230 240 250
SSFFTIASSH RALTEGAYLA AQLDTECPPC TTVAPQVLCF QQAFWNSKGN
260 270 280 290 300
YVVSTSTAGE YRSGKDANSI LASIHNFDPE AGCDNLTFQP CSERALANHK
310 320 330 340 350
AYVDSFRNLY AINKGIAQGK AVAVGRYSED VYYNGNPWYL ANFAAAEQLY
360 370 380 390 400
DAIYVWNKQG SITVTSVSLP FFRDLVSSVS TGTYSKSSST FTNIVNAVKA
410 420 430 440 450
YADGFIEVAA KYTPSNGALA EQYDRNTGKP DSAADLTWSY SAFLSAIDRR
460 470 480 490 500
AGLVPPSWRA SVAKSQLPST CSRIEVAGTY VAATSTSFPS KQTPNPSAAP
510 520 530 540 550
SPSPYPTACA DASEVYVTFN ERVSTAWGET IKVVGNVPAL GNWDTSKAVT
560 570 580 590 600
LSASGYKSND PLWSITVPIK ATGSAVQYKY IKVGTNGKIT WESDPNRSIT
610 620
LQTASSAGKC AAQTVNDSWR
Length:620
Mass (Da):66,525
Last modified:November 1, 1996 - v1
Checksum:i54214FF67E20BE0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M89475 Genomic DNA. Translation: AAA33386.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M89475 Genomic DNA. Translation: AAA33386.1.

3D structure databases

ProteinModelPortaliQ12623.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiCBM20. Carbohydrate-Binding Module Family 20.
GH15. Glycoside Hydrolase Family 15.

Proteomic databases

PRIDEiQ12623.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
2.60.40.10. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR013784. Carb-bd-like_fold.
IPR002044. CBM_fam20.
IPR000165. Glucoamylase.
IPR008291. Glucoamylase_SBD.
IPR011613. Glyco_hydro_15/PHK.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF00686. CBM_20. 1 hit.
PF00723. Glyco_hydro_15. 1 hit.
[Graphical view]
PIRSFiPIRSF001031. Glu-a-glcsd_SBD. 1 hit.
PRINTSiPR00736. GLHYDRLASE15.
SMARTiSM01065. CBM_2. 1 hit.
[Graphical view]
SUPFAMiSSF48208. SSF48208. 1 hit.
SSF49452. SSF49452. 1 hit.
PROSITEiPS51166. CBM20. 1 hit.
PS00820. GLUCOAMYLASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ12623_9PEZI
AccessioniPrimary (citable) accession number: Q12623
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 5, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.