Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Beta-1,4-xylanase

Gene

xynA

Organism
Dictyoglomus thermophilum
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

Pathway: xylan degradation

This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.
View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei155 – 1551Proton donorBy similarity
Active sitei262 – 2621NucleophileBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation

Enzyme and pathway databases

UniPathwayiUPA00114.

Protein family/group databases

CAZyiGH10. Glycoside Hydrolase Family 10.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-1,4-xylanase (EC:3.2.1.8)
Alternative name(s):
1,4-beta-D-xylan xylanohydrolase
Endo-1,4-beta-xylanase
Gene namesi
Name:xynA
OrganismiDictyoglomus thermophilum
Taxonomic identifieri14 [NCBI]
Taxonomic lineageiBacteriaDictyoglomiDictyoglomalesDictyoglomaceaeDictyoglomus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence AnalysisAdd
BLAST
Chaini24 – 352329Beta-1,4-xylanasePRO_0000184065Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi309799.DICTH_1538.

Structurei

3D structure databases

ProteinModelPortaliQ12603.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00331. Glyco_hydro_10. 1 hit.
[Graphical view]
PRINTSiPR00134. GLHYDRLASE10.
SMARTiSM00633. Glyco_10. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q12603-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINQRFSILV LLLILLTFSL GFLKEEAKGM EIPSLKEVYK DYFTIGAAVS
60 70 80 90 100
HLNIYHYENL LKKHFNSLTP ENQMKWEVIH PKPYVYDFGP ADEIVDFAMK
110 120 130 140 150
NGMKVRGHTL VWHNQTPGWV YAGTKDEILA RLKEHIKEVV GHYKGKVYAW
160 170 180 190 200
DVVNEALSDN PNEFLRRAPW YDICGEEVIE KAFIWAHEVD PDAKLFYNDY
210 220 230 240 250
NLEDPIKREK AYKLVKKLKD KGVPIHGIGI QGHWTLAWPT PKMLEDSIKR
260 270 280 290 300
FAELGVEVQV TEFDISIYYD RNENNNFKVP PEDRLERQAQ LYKEAFEILR
310 320 330 340 350
KYKGIVTGVT FWGVADDYTW LYFWPVRGRE DYPLLFDKNH NPKKAFWEIV

KF
Length:352
Mass (Da):41,486
Last modified:November 1, 1997 - v1
Checksum:i393F702B5B8AA9AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L39866 Genomic DNA. Translation: AAA96979.1.
PIRiT08469.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L39866 Genomic DNA. Translation: AAA96979.1.
PIRiT08469.

3D structure databases

ProteinModelPortaliQ12603.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi309799.DICTH_1538.

Protein family/group databases

CAZyiGH10. Glycoside Hydrolase Family 10.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00114.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00331. Glyco_hydro_10. 1 hit.
[Graphical view]
PRINTSiPR00134. GLHYDRLASE10.
SMARTiSM00633. Glyco_10. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Cloning, sequencing, and expression of a xylanase gene from the extreme thermophile Dictyoglomus thermophilum Rt46B.1 and activity of the enzyme on fiber-bound substrate."
    Gibbs M.D., Reeves R.A., Bergquist P.L.
    Appl. Environ. Microbiol. 61:4403-4408(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Rt46 B.1.

Entry informationi

Entry nameiXYNA_DICTH
AccessioniPrimary (citable) accession number: Q12603
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 24, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.