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Q12603 (XYNA_DICTH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-1,4-xylanase

EC=3.2.1.8
Alternative name(s):
1,4-beta-D-xylan xylanohydrolase
Endo-1,4-beta-xylanase
Gene names
Name:xynA
OrganismDictyoglomus thermophilum
Taxonomic identifier14 [NCBI]
Taxonomic lineageBacteriaDictyoglomiDictyoglomalesDictyoglomaceaeDictyoglomus

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

Pathway

Glycan degradation; xylan degradation.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 10 (cellulase F) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Polysaccharide degradation
Xylan degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
Gene Ontology (GO)
   Biological_processxylan catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionendo-1,4-beta-xylanase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 352329Beta-1,4-xylanase
PRO_0000184065

Sites

Active site1551Proton donor By similarity
Active site2621Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q12603 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 393F702B5B8AA9AB

FASTA35241,486
        10         20         30         40         50         60 
MINQRFSILV LLLILLTFSL GFLKEEAKGM EIPSLKEVYK DYFTIGAAVS HLNIYHYENL 

        70         80         90        100        110        120 
LKKHFNSLTP ENQMKWEVIH PKPYVYDFGP ADEIVDFAMK NGMKVRGHTL VWHNQTPGWV 

       130        140        150        160        170        180 
YAGTKDEILA RLKEHIKEVV GHYKGKVYAW DVVNEALSDN PNEFLRRAPW YDICGEEVIE 

       190        200        210        220        230        240 
KAFIWAHEVD PDAKLFYNDY NLEDPIKREK AYKLVKKLKD KGVPIHGIGI QGHWTLAWPT 

       250        260        270        280        290        300 
PKMLEDSIKR FAELGVEVQV TEFDISIYYD RNENNNFKVP PEDRLERQAQ LYKEAFEILR 

       310        320        330        340        350 
KYKGIVTGVT FWGVADDYTW LYFWPVRGRE DYPLLFDKNH NPKKAFWEIV KF 

« Hide

References

[1]"Cloning, sequencing, and expression of a xylanase gene from the extreme thermophile Dictyoglomus thermophilum Rt46B.1 and activity of the enzyme on fiber-bound substrate."
Gibbs M.D., Reeves R.A., Bergquist P.L.
Appl. Environ. Microbiol. 61:4403-4408(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Rt46 B.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L39866 Genomic DNA. Translation: AAA96979.1.
PIRT08469.

3D structure databases

ProteinModelPortalQ12603.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH10. Glycoside Hydrolase Family 10.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00114.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00331. Glyco_hydro_10. 1 hit.
[Graphical view]
PRINTSPR00134. GLHYDRLASE10.
SMARTSM00633. Glyco_10. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
ProtoNetSearch...

Entry information

Entry nameXYNA_DICTH
AccessionPrimary (citable) accession number: Q12603
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: February 19, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries