Reviewed, UniProtKB/Swiss-Prot Q12603 (XYNA_DICTH)

Names and origin

Protein names

Recommended name:
    Beta-1,4-xylanase
    EC=3.2.1.8
Alternative name(s):
    Endo-1,4-beta-xylanase
    1,4-beta-D-xylan xylanohydrolase

Gene names

Name:

xynA

Organism

Dictyoglomus thermophilum

Taxonomic identifier

14 [NCBI]

Taxonomic lineage

Bacteria › Dictyoglomi › Dictyoglomales › Dictyoglomaceae › Dictyoglomus

Protein attributes

Sequence length	352 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Subcellular location	Secreted By similarity.
Sequence similarities	Belongs to the glycosyl hydrolase 10 (cellulase F) family.

Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 23	23	Potential
	Chain	24 – 352	329	Beta-1,4-xylanase		PRO_0000184065
Sites
	Active site	155	1	Proton donor By similarity
	Active site	262	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q12603-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 393F702B5B8AA9AB	FASTA	352	41,486
	10 20 30 40 50 60 MINQRFSILV LLLILLTFSL GFLKEEAKGM EIPSLKEVYK DYFTIGAAVS HLNIYHYENL 70 80 90 100 110 120 LKKHFNSLTP ENQMKWEVIH PKPYVYDFGP ADEIVDFAMK NGMKVRGHTL VWHNQTPGWV 130 140 150 160 170 180 YAGTKDEILA RLKEHIKEVV GHYKGKVYAW DVVNEALSDN PNEFLRRAPW YDICGEEVIE 190 200 210 220 230 240 KAFIWAHEVD PDAKLFYNDY NLEDPIKREK AYKLVKKLKD KGVPIHGIGI QGHWTLAWPT 250 260 270 280 290 300 PKMLEDSIKR FAELGVEVQV TEFDISIYYD RNENNNFKVP PEDRLERQAQ LYKEAFEILR 310 320 330 340 350 KYKGIVTGVT FWGVADDYTW LYFWPVRGRE DYPLLFDKNH NPKKAFWEIV KF

References

[1]

"Cloning, sequencing, and expression of a xylanase gene from the extreme thermophile Dictyoglomus thermophilum Rt46B.1 and activity of the enzyme on fiber-bound substrate." Gibbs M.D., Reeves R.A., Bergquist P.L. Appl. Environ. Microbiol. 61:4403-4408(1995) [PubMed: 8534104] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Rt46 B.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L39866 Genomic DNA. Translation: AAA96979.1.
PIR	T08469.
3D structure databases
SMR	Q12603. Positions 31-351.
ModBase	Search...
Protein family/group databases
CAZy	GH10. Glycoside Hydrolase Family 10.
Enzyme and pathway databases
BRENDA	3.2.1.8. 141232.
Family and domain databases
InterPro	IPR001000. Glyco_hydro_10. IPR017853. Glyco_hydro_catalytic_core. IPR013781. Glyco_hydro_sg_catalytic. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
Pfam	PF00331. Glyco_hydro_10. 1 hit. [Graphical view]
PRINTS	PR00134. GLHYDRLASE10.
SMART	SM00633. Glyco_10. 1 hit. [Graphical view]
PROSITE	PS00591. GLYCOSYL_HYDROL_F10. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYNA_DICTH

Accession

Primary (citable) accession number: Q12603

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	January 19, 2010
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)