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Protein

WD repeat-containing protein YPL247C

Gene

YPL247C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-34133-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
WD repeat-containing protein YPL247C
Gene namesi
Ordered Locus Names:YPL247C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPL247C.
SGDiS000006168. YPL247C.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002424901 – 523WD repeat-containing protein YPL247CAdd BLAST523

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei47PhosphoserineCombined sources1
Modified residuei65PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ12523.
PRIDEiQ12523.

PTM databases

iPTMnetiQ12523.

Interactioni

Protein-protein interaction databases

BioGridi35916. 8 interactors.
DIPiDIP-6366N.
IntActiQ12523. 6 interactors.
MINTiMINT-685692.

Structurei

3D structure databases

ProteinModelPortaliQ12523.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati173 – 213WD 1Add BLAST41
Repeati241 – 281WD 2Add BLAST41
Repeati285 – 325WD 3Add BLAST41
Repeati392 – 432WD 4Add BLAST41

Sequence similaritiesi

Belongs to the WD repeat WDR68 family.Curated
Contains 4 WD repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

GeneTreeiENSGT00390000006939.
HOGENOMiHOG000260968.
InParanoidiQ12523.
KOiK11805.
OMAiAHSTIIY.
OrthoDBiEOG092C2KT9.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 2 hits.
[Graphical view]
SMARTiSM00320. WD40. 4 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q12523-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPFHNGNKR SSISFGSSQR QPYNKNNYLS GTNGPSSAAQ DQGRGPSPFG
60 70 80 90 100
MSGNTTNGGN SKRNSGCDLS ATYYASRSPM YSPLDFSPPV FSPNHSQLQQ
110 120 130 140 150
ARGYAANIPV VSNLMNPSMA SVCEYQSHYP LFGLDWSADD YVCLGSYKED
160 170 180 190 200
SRNKLQVLHS NDLLSWESVV DADVVYPVSK IQWVPSQLYP RKLATCSDSL
210 220 230 240 250
RIWSVSPEER QFQEQINLSL CKYNRQHPAN PAAADDMKVI GTFPPITSFD
260 270 280 290 300
WNTVDTNLII SSSIDTTCIV WDLQSSHYVK TQLIAHDSEV FDVRFLTKST
310 320 330 340 350
QLFASCGGDG SVRVFDLRSL AHSTIIYEPP SSSVSGATAG TITPSSKGSD
360 370 380 390 400
ALLRLEPSPY DPNVLATFAA DSNKIIILDM RNPESPILNL QGHGSSVNGI
410 420 430 440 450
KWHPTKRNVL LSCGDDCQVL YWDLNSSFME INAAGSKSPS IHGTSLEDPD
460 470 480 490 500
GDTEMTDGGA GSGLNEDPLS LNNNSKQVCK TLETPNMMYA NKTQEINNIA
510 520
WRPQRGDWFG CVSGKKFQNV RVL
Length:523
Mass (Da):57,324
Last modified:November 1, 1996 - v1
Checksum:i02CE191AB77E712C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z67751 Genomic DNA. Translation: CAA91597.1.
Z73603 Genomic DNA. Translation: CAA97968.1.
BK006949 Genomic DNA. Translation: DAA11190.1.
PIRiS61017.
RefSeqiNP_015077.1. NM_001184061.1.

Genome annotation databases

EnsemblFungiiYPL247C; YPL247C; YPL247C.
GeneIDi855829.
KEGGisce:YPL247C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z67751 Genomic DNA. Translation: CAA91597.1.
Z73603 Genomic DNA. Translation: CAA97968.1.
BK006949 Genomic DNA. Translation: DAA11190.1.
PIRiS61017.
RefSeqiNP_015077.1. NM_001184061.1.

3D structure databases

ProteinModelPortaliQ12523.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35916. 8 interactors.
DIPiDIP-6366N.
IntActiQ12523. 6 interactors.
MINTiMINT-685692.

PTM databases

iPTMnetiQ12523.

Proteomic databases

MaxQBiQ12523.
PRIDEiQ12523.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYPL247C; YPL247C; YPL247C.
GeneIDi855829.
KEGGisce:YPL247C.

Organism-specific databases

EuPathDBiFungiDB:YPL247C.
SGDiS000006168. YPL247C.

Phylogenomic databases

GeneTreeiENSGT00390000006939.
HOGENOMiHOG000260968.
InParanoidiQ12523.
KOiK11805.
OMAiAHSTIIY.
OrthoDBiEOG092C2KT9.

Enzyme and pathway databases

BioCyciYEAST:G3O-34133-MONOMER.

Miscellaneous databases

PROiQ12523.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 2 hits.
[Graphical view]
SMARTiSM00320. WD40. 4 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYP247_YEAST
AccessioniPrimary (citable) accession number: Q12523
Secondary accession number(s): D6W3C4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 134 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 799 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.