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Protein

WD repeat-containing protein YPL247C

Gene

YPL247C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 799 molecules/cell in log phase SD medium.1 Publication

Enzyme and pathway databases

BioCyciYEAST:G3O-34133-MONOMER
ReactomeiR-SCE-8951664 Neddylation

Names & Taxonomyi

Protein namesi
Recommended name:
WD repeat-containing protein YPL247C
Gene namesi
Ordered Locus Names:YPL247C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPL247C
SGDiS000006168 YPL247C

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002424901 – 523WD repeat-containing protein YPL247CAdd BLAST523

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei47PhosphoserineCombined sources1
Modified residuei65PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ12523
PaxDbiQ12523
PRIDEiQ12523

PTM databases

iPTMnetiQ12523

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
HSP60P198823EBI-37062,EBI-8586

Protein-protein interaction databases

BioGridi35916, 38 interactors
DIPiDIP-6366N
IntActiQ12523, 11 interactors
MINTiQ12523
STRINGi4932.YPL247C

Structurei

3D structure databases

ProteinModelPortaliQ12523
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati173 – 213WD 1Add BLAST41
Repeati241 – 281WD 2Add BLAST41
Repeati285 – 325WD 3Add BLAST41
Repeati392 – 432WD 4Add BLAST41

Sequence similaritiesi

Belongs to the WD repeat WDR68 family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

GeneTreeiENSGT00390000006939
HOGENOMiHOG000260968
InParanoidiQ12523
KOiK11805
OMAiAHSTIIY
OrthoDBiEOG092C2KT9

Family and domain databases

InterProiView protein in InterPro
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF00400 WD40, 2 hits
SMARTiView protein in SMART
SM00320 WD40, 4 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

Q12523-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPFHNGNKR SSISFGSSQR QPYNKNNYLS GTNGPSSAAQ DQGRGPSPFG
60 70 80 90 100
MSGNTTNGGN SKRNSGCDLS ATYYASRSPM YSPLDFSPPV FSPNHSQLQQ
110 120 130 140 150
ARGYAANIPV VSNLMNPSMA SVCEYQSHYP LFGLDWSADD YVCLGSYKED
160 170 180 190 200
SRNKLQVLHS NDLLSWESVV DADVVYPVSK IQWVPSQLYP RKLATCSDSL
210 220 230 240 250
RIWSVSPEER QFQEQINLSL CKYNRQHPAN PAAADDMKVI GTFPPITSFD
260 270 280 290 300
WNTVDTNLII SSSIDTTCIV WDLQSSHYVK TQLIAHDSEV FDVRFLTKST
310 320 330 340 350
QLFASCGGDG SVRVFDLRSL AHSTIIYEPP SSSVSGATAG TITPSSKGSD
360 370 380 390 400
ALLRLEPSPY DPNVLATFAA DSNKIIILDM RNPESPILNL QGHGSSVNGI
410 420 430 440 450
KWHPTKRNVL LSCGDDCQVL YWDLNSSFME INAAGSKSPS IHGTSLEDPD
460 470 480 490 500
GDTEMTDGGA GSGLNEDPLS LNNNSKQVCK TLETPNMMYA NKTQEINNIA
510 520
WRPQRGDWFG CVSGKKFQNV RVL
Length:523
Mass (Da):57,324
Last modified:November 1, 1996 - v1
Checksum:i02CE191AB77E712C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z67751 Genomic DNA Translation: CAA91597.1
Z73603 Genomic DNA Translation: CAA97968.1
BK006949 Genomic DNA Translation: DAA11190.1
PIRiS61017
RefSeqiNP_015077.1, NM_001184061.1

Genome annotation databases

EnsemblFungiiYPL247C; YPL247C; YPL247C
GeneIDi855829
KEGGisce:YPL247C

Similar proteinsi

Entry informationi

Entry nameiYP247_YEAST
AccessioniPrimary (citable) accession number: Q12523
Secondary accession number(s): D6W3C4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 145 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health