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Reviewed, UniProtKB/Swiss-Prot Q12510 (YD156_YEAST)

Last modified November 3, 2009. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    WD repeat-containing protein YDL156W
Gene names
Ordered Locus Names: YDL156W
ORF Names: D1536
OrganismSaccharomyces cerevisiae (Baker's yeast) [Complete proteome]
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

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Protein attributes

Sequence length522 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Subcellular location

Cytoplasm. Nucleus. Ref.3

Miscellaneous

Present with 3810 molecules/cell in log phase SD medium. Ref.4

Sequence similarities

Belongs to the WD repeat DDB2/WDR76 family.

Contains 7 WD repeats.

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Ontologies

Keywords
   Cellular componentCytoplasm
Nucleus
   DomainRepeat
WD repeat
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm Ref.3

Inferred from direct assay. Source: SGD

nucleus Ref.3

Inferred from direct assay. Source: SGD

   Molecular functionprotein binding

Inferred from physical interaction. Source: IntAct

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 522522WD repeat-containing protein YDL156W
PRO_0000240874

Regions

Repeat183 – 22442WD 1
Repeat239 – 28143WD 2
Repeat287 – 32741WD 3
Repeat331 – 37141WD 4
Repeat388 – 42740WD 5
Repeat442 – 48140WD 6
Repeat482 – 52140WD 7

Amino acid modifications

Modified residue641Phosphoserine Ref.6
Modified residue691Phosphothreonine Ref.5
Modified residue2241Phosphoserine Ref.6

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Sequences

Sequence LengthMass (Da)Tools
Q12510-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 3BE716E4858EF3E8

FASTA52259,156
        10         20         30         40         50         60 
MPELTEFQKK RLENIKRNND LLKKLHLSGV ASQIKHEAGV LEKSRAPAKK KQKTTNTRAT 

        70         80         90        100        110        120 
KSASPTLPTR RSRRLRGESA DDVKGIPNVN DNQLLKMGSP DGQDKNFIDA IKEKPVIGDV 

       130        140        150        160        170        180 
KLSDLIKDED ESALLEKFKR FNNGNFSSGD FFEEIKKRQG DVTGMDEFDL DLYDVFQPNE 

       190        200        210        220        230        240 
IKITYERISA TYFHPAMEKK LIIAGDTSGT VGFWNVRDEP LADSEEDRME EPDITRVKLF 

       250        260        270        280        290        300 
TKNVGRIDCF PADTSKILLT SYDGSIRSVH LNNLQSEEVL TLKNEYDDSL GISDCQFSYE 

       310        320        330        340        350        360 
NPNVLFLTTL GGEFTTFDTR VKKSEYNLRR LADKKIGSMA INPMRPYEIA TGSLDRTLKI 

       370        380        390        400        410        420 
WDTRNLVKKP EWSQYEDYPS HEIVSTYDSR LSVSAVSYSP TDGTLVCNGY DDTIRLFDVK 

       430        440        450        460        470        480 
SRDHLSAKLE PKLTIQHNCQ TGRWTSILKA RFKPNKNVFA IANMKRAIDI YNSEGQQLAH 

       490        500        510        520 
LPTATVPAVI SWHPLRNWIA GGNSSGKIFL FTDDSGTIKQ EE

« Hide

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References

« Hide 'large scale' references
[1]"Analysis of a 23 kb region on the left arm of yeast chromosome IV."
Delaveau T.T.D., Blugeon C., Jacq C., Perea J.
Yeast 12:1587-1592(1996) [PubMed: 8972581] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 90840 / EAY235 / FY23.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T. expand/collapse author list , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
Nature 387:75-78(1997) [PubMed: 9169867] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed: 14562095] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry."
Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.
Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed: 17287358] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-69, MASS SPECTROMETRY.
[6]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-64 AND SER-224, MASS SPECTROMETRY.
+Additional computationally mapped references.

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Cross-references

Sequence databases

X97751 Genomic DNA. Translation: CAA66335.1.
Z74204 Genomic DNA. Translation: CAA98730.1.
PIRS67704.
RefSeqNP_010125.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

DIPDIP:1004N.
IntActQ12510. 17 interactions.
STRINGQ12510.

Proteomic databases

PeptideAtlasQ12510.
PRIDEQ12510.

Genome annotation databases

EnsemblYDL156W; YDL156W; YDL156W; Saccharomyces cerevisiae. [Genome view]
GeneID851399.
GenomeReviewsGene locus YDL156W in contig Z71256_GR.
KEGGsce:YDL156W.
NMPDRfig|4932.3.peg.862.

Organism-specific databases

CYGDYDL156w.
SGDS000002315. YDL156W.

Phylogenomic databases

HOGENOMQ12510.
OMANCQTGRW.

Gene expression databases

ArrayExpressQ12510.
GenevestigatorQ12510.
GermOnlineYDL156W. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019782. WD40_repeat_2.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
IPR019781. WD40_repeat_sg.
[Graphical view]
Gene3DG3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
PfamPF00400. WD40. 2 hits.
[Graphical view]
SMARTSM00320. WD40. 4 hits.
[Graphical view]
PROSITEPS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio968564.

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Entry information

Entry nameYD156_YEAST
AccessionPrimary (citable) accession number: Q12510
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 1, 1996
Last modified: November 3, 2009
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents